8.3Uterine surgery: leiomyoma

StudyPopulationInterventionOutcomesResultsCommentsStudy typeEL
Seracchioli et al. 2000655131 women with at least one large myomalaparoscopic (n = 56) versus abdominal (n = 59)
Pregnancy rate

Miscarriage rate

Ectopic pregnancy

Live births

Preterm delivery rate

Postoperative outcomes: drop in Hb, fever, hospital stay
No significant differences

Pregnancy rate:
Laparoscopic: 30/56 (54%)
Abdominal: 33/59 (56%)

Miscarriage rate:
Laparoscopic: 6/30 (20%)
Abdominal: 4/33 (12%)

Ectopic pregnancy:
Laparoscopic: 1
Abdominal: 0

Live births:
Laparoscopic: 20
Abdominal: 27

Preterm delivery rate:
Laparoscopic: 1/20 (5%)
Abdominal: 2/27 (7%)

Postoperative outcomes significantly higher in abdominal group
Randomisation by use of total random digits

12 months of follow-up

From: Evidence tables

Cover of Fertility
Fertility: Assessment and Treatment for People with Fertility Problems.
NICE Clinical Guidelines, No. 11.
National Collaborating Centre for Women's and Children's Health (UK).
London (UK): RCOG Press; 2004 Feb.
Copyright © 2004, National Collaborating Centre for Women’s and Children’s Health.

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