8.3Uterine surgery: leiomyoma

StudyPopulationInterventionOutcomesResultsCommentsStudy typeEL
Seracchioli et al. 2000655131 women with at least one large myomalaparoscopic (n = 56) versus abdominal (n = 59)
myomectomy
Pregnancy rate

Miscarriage rate

Ectopic pregnancy

Live births

Preterm delivery rate

Postoperative outcomes: drop in Hb, fever, hospital stay
No significant differences

Pregnancy rate:
Laparoscopic: 30/56 (54%)
Abdominal: 33/59 (56%)

Miscarriage rate:
Laparoscopic: 6/30 (20%)
Abdominal: 4/33 (12%)

Ectopic pregnancy:
Laparoscopic: 1
Abdominal: 0

Live births:
Laparoscopic: 20
Abdominal: 27

Preterm delivery rate:
Laparoscopic: 1/20 (5%)
Abdominal: 2/27 (7%)

Postoperative outcomes significantly higher in abdominal group
Randomisation by use of total random digits

12 months of follow-up
RCTIb

From: Evidence tables

Cover of Fertility
Fertility: Assessment and Treatment for People with Fertility Problems.
NICE Clinical Guidelines, No. 11.
National Collaborating Centre for Women's and Children's Health (UK).
London (UK): RCOG Press; 2004 Feb.
Copyright © 2004, National Collaborating Centre for Women’s and Children’s Health.

Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.