5.3Chlamydia trachomatis: incidence

StudyPopulationInterventionOutcomesResultsCommentsStudy typeEL
Scholes et al. 19963642607 women identified from data base of Group Health Cooperative Scheme, aged 18–24 years

Screening: (n = 1009)

Usual care: (n = 1598)

Exclusion: married, pregnant, cervical ectopy

Baseline characteristics comparable
Women invited for screening (2 cervical samples tested) versus usual care (attend as needed)

Women testing positive were treated
Incidence of pelvic inflammatory disease confirmed by medical records

Rates expressed as per 10,000 woman-months
Screening: 9 cases

Usual care: 33 cases

Rates: screening: 8; usual care: 18

Adjusted RR 0.44 (CI 0.20 to 0.90)
Screening group: 645/1009 (64%) tested, 7% positive and treated

12 month follow-up

Response rate: 76%

Method of randomisation and allocation concealment unclear

Data extractors ‘blind’

Intention-to-treat analysis
RCTIb

From: Evidence tables

Cover of Fertility
Fertility: Assessment and Treatment for People with Fertility Problems.
NICE Clinical Guidelines, No. 11.
National Collaborating Centre for Women's and Children's Health (UK).
London (UK): RCOG Press; 2004 Feb.
Copyright © 2004, National Collaborating Centre for Women’s and Children’s Health.

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