Table B.12Cost per live birth using baseline cost for intracytoplasmic sperm injection

All agesLive birth rate (fresh embryo transfer) (%)17.6
Cost (£)2,936Ectopic pregnancy rate (%)0.5
Discontinuation rate (%)17.7Miscarriage rate (%)2.7
OHSS rate (%)0.2Live birth rate (frozen embryo transfer) (%)11.5
Cycle
123456
Cumulative fresh cycles (n)100016292025227424312530
Cumulative frozen embryo transfer (n)5188431048117712601311
Cumulative couples with baby (n)236384477536572595
Cumulative ectopic pregnancy51013151617
Cumulative Miscarriage41678393100104
Cumulative OHSS2.003.264.054.554.865.06
Discontinuation1358554342176
Cumulative discontinuation rate138220274308329405
Total cost per cycle for 1000 couples (£)3,297,9742,074,9201,305,436821,315517,516327,892
Cumulative cost per cycle for 1000 couples (£)3,297,9745,372,8946,678,3307,499,6458,017,1618,345,053
Cost per live birth (all cycles) (£)14,002

From: Appendix B, Economic models

Cover of Fertility
Fertility: Assessment and Treatment for People with Fertility Problems.
NICE Clinical Guidelines, No. 11.
National Collaborating Centre for Women's and Children's Health (UK).
London (UK): RCOG Press; 2004 Feb.
Copyright © 2004, National Collaborating Centre for Women’s and Children’s Health.

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