Table 40Frequency and percentage of presented signs(430)

Presenting signFrequency%Presenting signFrequency%
White reflex (leukocoria)71056.1Macrophthalmia/buphthalmia90.7
Strabismus29823.6Photophobia70.6
 Direction not specified997.8Conjunctivitis60.5
 Estropia13310.5Headaches60.5
 Exotropia665.2Proptosis60.5
Unknown presenting sign1259.9Vomiting60.5
Poor vision987.7Kept eye closed50.4
Family history866.8Microphthalmia40.3
Irritation544.3Orbital cellulitis30.2
Routine examination (including for trauma)362.8Anorexia/failure to thrive Hyphema20.2
‘Something looked wrong’252.0Metastasis/growths20.2
Anisocoria241.9Nausea20.2
Heterochromia iridis231.8Ptosis20.2
Inflammation231.8Aniridia10.1
Pain191.5Phthisis10.1
Discharge161.3Ruptured globe10.1
Nystagmus131.0Vitreous haemorrhage10.1

Presenting signs and symptoms of retinoblastoma (n=1265)

From: 20, Children’s and Young People’s Cancer

Cover of Referral Guidelines for Suspected Cancer in Adults and Children
Referral Guidelines for Suspected Cancer in Adults and Children [Internet].
NICE Clinical Guidelines, No. 27.
Clinical Governance Research and Development Unit (CGRDU), Department of Health Sciences, University of Leicester.
Copyright © 2005, National Collaborating Centre for Primary Care.

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