Table D2mOropharyngeal cancer, patient survival

StudyRec#No. PtsSettingGroup% Stage III/IVOutcome1 yr2 yr3 yr4 yr5 yrp valueComments
RT + CCTx
IMRT vs 3DCRT
Rusthoven, 20081320087RT + CCTxIMRT
3DCRT
100
100
OS~90
~80
86
73
~72
~70
~72
~55
0.48RT tech NS in MVA
IMRT vs 2DRT
Lee, 20062350112RT + CCTxIMRT
2DRT
100
98.6
OS~100
~88
~96
~88
91
81
91
~70
91
~70
0.10
Mixed Settings
IMRT vs 3DCRT
Hodge, 2007570195RT ± CCTxIMRT
3DCRT
3DCRTpre
86
100
78
DSS~99
~98
~93
97.7
83.5
87.7
97.7
83.5
79.7
97.7
83.5
~76
73.5NR
IMRT 3DCRT 3DCRTpreOS~98
~95
~90
94.5
81.1
87.7
88.2
81.1
79.7
88.2
81.1
~56
54.60.02pre=preIMRT era RT tech NS in MVA (w/T stage)
Rades, 2007271044postop RT ± CCTxIMRT
3DCRT
≥50
≥65
OS86
80
0.30RT tech NS in MVA
Nutting, 20094122084RT/postop ± preRT CTxIMRT
3DCRT
77 (all)OS93.6
90.8
NSIMRT:3DCRT
HR=1.05 (0.38, 2.90)
3DCRT vs 2DRT
Rades, 20072710130postop RT ± CCTx3DCRT
2DRT
≥65
≥54
OS80
74
0.30RT tech NS in MVA
IMRT vs 2DRT
Rades, 20072710122postop RT ± CCTxIMRT
2DRT
≥50
≥54
OS86
74
0.30RT tech NS in MVA
Chao, 200199404301º/preop/postop RT ± CCTxdefIMRT
def2DRT
postopIM
RT
postop2D
RT
preop2DR
T
91.7
63.7
85.7
86.7
71.6
OS100
57
100
71
67
0.001

0.003

From: Appendix D, Comparative Studies: Full Evidence/Data Abstraction Tables

Cover of Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer
Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer [Internet].
Comparative Effectiveness Reviews, No. 20.
Samson DJ, Ratko TA, Rothenberg BM, et al.

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