Table D1bNasopharyngeal cancer, participants and treatments

StudyRec#No. PtsSettingTx Group% FemaleMedian Age (rng, yrs)% Stage III/IVPrescribed RT Dose to Primary Tumor (Gy)Median Follow-up (rng, mos)Completed RT (%)
RT
3DCRT vs 2DRT
Jen, 20055240180RT3DCRT
2DR
15
18
43 (19–80)
44 (18–84)
59.7
58.3
70 (all)26100 (all)
IMRT vs 2DRT
Pow, 2006 (RCT)234045RTIMRT
2DR
25
19
46 (26–69)
50 (37–75)
0 (all)68
68–72
NRNR
Wu, 20054520380RTIMRT
2DR
32 (all)38 (15–64) (all)85.8 (all)75
70
NRNR
RT + split CTx
3DCRT vs 2DRT
Wu, 2005 (RCT)436096RT + split CTx3DCRT
2DR
35
34
45 (16–68)
44 (18–67)
100 (all)66–86 (all)NRNR
IMRT vs 2DRT
Laskar, 20083905036RT + split CTxIMRT
2DR
26
18
14 (5–18) (all)84.2
94.1
70 (all)27 (4–42)100
88
Mixed Settings
IMRT vs 3DCRT
Fang, 2007225085RT ± CTx (timing?)IMRT
3DCRT
33
24
49
51
48.1
48.5
65–76 (all)NRNR
Fang, 200839090203RT ± CCTxIMRT
3DCRT
22
17
NR52.8
55.9
65–76 (all)40 (5–57)
46 (10–59)
NR
3DCRT vs 2DRT
Fang, 2007225094RT ± CTx (timing?)3DCRT
2DR
24
28
51
51
48.1
50.8
65–76 (all)46 (10–59)NR
IMRT vs 2DRT
Kam, 2007 (RCT)53056RT ± ICBRTIMRT
2DR
25
32
46
50
0 (all)66 + 18 Gy ICB
66 + 12 Gy ICB
NR100 (all)
Fang, 20072250113RT ± CTx (timing?)IMRT
2DR
29
28
49
51
48.5
50.8
60–70 (all)NRNR
Hsiung, 2006307032RT± CCTxIMRT
2DR
31
25
NR50
37.5
67–70
68–76
24 (14–34)NR

From: Appendix D, Comparative Studies: Full Evidence/Data Abstraction Tables

Cover of Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer
Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer [Internet].
Comparative Effectiveness Reviews, No. 20.
Samson DJ, Ratko TA, Rothenberg BM, et al.

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