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Wolff T, Witkop CT, Miller T, et al. Folic Acid Supplementation for the Prevention of Neural Tube Defects: An Update of the Evidence for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2009 May. (Evidence Syntheses, No. 70.)

Appendix 1: PubMed search terms and exclusion criteria

PubMed search terms and limits:

(“neural tube defects”[MeSH Terms] OR “spina bifida”[All Fields] OR “neural tube damage”[All Fields] OR “neural tube defect”[All Fields] OR “neural tube defects”[All Fields] OR “neural tube disorders”[All Fields] AND ((“1995/01/01”[PDAT] : “2007/11/30”[PDAT]) AND English[lang])) AND ((“folic acid”[MeSH Terms] OR folic acid[Text Word]) AND ((“1995/01/01”[PDAT] : “2007/11/30”[PDAT]) AND English[lang])) AND ((“pregnancy”[MeSH Terms] OR pregnancy[Text Word]) AND ((“1995/01/01”[PDAT] : “2007/11/30”[PDAT]) AND English[lang])) AND

Exclusion Criteria for Folic Acid in Pregnancy Review

1.

A study not on folic acid supplementation

2.

Incorrect study type

3.

In a setting not generalizable to US

4.

Not in women of child bearing age

5.

No outcomes of interest

6.

High risk or special population (ex. Prior NTD)

7.

n < 100

8.

Duplicate study

Cover of Folic Acid Supplementation for the Prevention of Neural Tube Defects
Folic Acid Supplementation for the Prevention of Neural Tube Defects: An Update of the Evidence for the U.S. Preventive Services Task Force [Internet].
Evidence Syntheses, No. 70.
Wolff T, Witkop CT, Miller T, et al.

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