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Screening for Hepatitis C Virus Infection [Internet]

Screening for Hepatitis C Virus Infection [Internet]

Systematic Evidence Reviews - Agency for Healthcare Research and Quality (US)

Version: March 2004

Introduction

In this systematic review, we focus on whether it is useful to test for anti-hepatitis C virus (anti-HCV) antibody (Ab) in asymptomatic adults who have no history of liver disease or known liver function test abnormalities. The review is intended for use by the US Preventive Services Task Force (USPTF), which will make recommendations regarding screening in the general adult population or high-risk subpopulations.

Results

We identified no randomized trials or observational studies comparing outcomes between patients in the general adult population or high-risk subpopulations screened and not screened for hepatitis C. Although blood donors are routinely screened for HCV infection in order to insure the safety of transfused blood products, we also searched for studies demonstrating improvement in clinical outcomes in volunteer blood donors screened versus those not screened, and found none.

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