Table F3Age adjusted cumulative incidence of DCIS per 100,000 U.S. female population (results from individual studies conducted in the United States are sorted by the year of the events)

StudyDCISCumulative Incidence
Zheng, 199717
Year of the study: 1976–92
Data source: Connecticut Tumor Registry
Method to diagnose DCIS: Mammography
Inclusion age: ≥30 years
DCIS cases: 96
Year of events: 1973–75
Age-adjusted incidence rates standardized to 1970 per 100,000 female population: 1.87
Method to diagnose DCIS: Mammography
Inclusion age: ≥30 years
DCIS cases: 97
Year of events: 1976–78
Age-adjusted incidence rates standardized to 1970 per 100,000 female population: 1.84
Method to diagnose DCIS: Mammography
Inclusion age: ≥30 years
DCIS cases: 126
Year of events: 1979–81
Age-adjusted incidence rates standardized to 1970 per 100,000 female population: 2.37
Kumar, 200543
Year of the study: 1980–2002
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: N/S
Inclusion age: N/S years
DCIS cases: 4
Year of events: 1980
Annual age-adjusted incidence rates per 100,000 (2000 U.S. female population): 4
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 4
Year of events: 1980
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 4
Sumner, 200756
Year of the study: 1981–2001
Data source: Florida Cancer Data System
Method to diagnose DCIS: Mammography
Inclusion age: 18–103 years
DCIS cases: 23,810
Year of events: 1981
Age-adjusted Incidence rates per 100,000 standardized to the U.S. population: 2.4
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 4
Year of events: 1981
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 4
Zheng, 199717
Year of the study: 1976–92
Data source: Connecticut Tumor Registry
Method to diagnose DCIS: Mammography
Inclusion age: ≥30 years
DCIS cases: 176
Year of events: 1982–84
Age-adjusted incidence rates standardized to the 1970 per 100,000 female population: 3.19
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 5
Year of events: 1982
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 5
Kumar, 200543
Year of the study: 1980–2002
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: N/S
Inclusion age: N/S years
DCIS cases: 5
Year of events: 1983
Annual age-adjusted incidence rates per 100,000 (2000 U.S. female population): 5
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 5
Year of events: 1983
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 5
Kumar, 200543
Year of the study: 1980–2002
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: N/S
Inclusion age: N/S years
DCIS cases: 7.8
Year of events: 1984
Annual age-adjusted incidence rates per 100,000 (2000 U.S. female population): 7.8
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 8
Year of events: 1984
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 8
Zheng, 199717
Year of the study: 1976–92
Data source: Connecticut Tumor Registry
Method to diagnose DCIS: Mammography
Inclusion age: ≥30 years
DCIS cases: 483
Year of events: 1985–87
Age-adjusted incidence rates standardized to 1970 per 100,000 female population: 8.5
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 11
Year of events: 1985
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 11
Method to diagnose DCIS: Individual patient records
Inclusion age:≥30 years
DCIS cases: 13.5
Year of events: 1986
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 13.5
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 12.5
Year of events: 1987–1989
Cumulative incidence rate per 100,000 over 2 years: 12.5
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 10
Year of events: 1987
Cumulative incidence rate per 100,000 over 1 year: 10
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 18
Year of events: 1987
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 18
Zheng, 199717
Year of the study: 1976–92
Data source: Connecticut Tumor Registry
Method to diagnose DCIS: Mammography
Inclusion age: ≥30 years
DCIS cases: 698
Year of events: 1988–90
Age-adjusted incidence rates standardized to the 1970 per 100,000 female population: 11.84
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 13
Year of events: 1988
Cumulative incidence rate per 100,000 over 1 year: 13
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 19
Year of events: 1988
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 19
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 16
Year of events: 1989
Cumulative incidence rate per 100,000 over 1 year: 16
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 18
Year of events: 1989
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 18
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 15
Year of events: 1990
Cumulative incidence rate per 100,000 over 1 year: 15
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 22
Year of events: 1990
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 22
Zheng, 199717
Year of the study: 1976–92
Data source: Connecticut Tumor Registry
Method to diagnose DCIS: Mammography
Inclusion age: ≥30 years
DCIS cases: 567
Year of events: 1991–92
Age-adjusted incidence rates standardized to 1970 per 100,000 female population: 14.06
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 20
Year of events: 1991
Cumulative incidence rate per 100,000 over 1 year: 20
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 22.5
Year of events: 1991
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 22.5
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 17
Year of events: 1992
Cumulative incidence rate per 100,000 over 1 year: 17
Kumar, 200543
Year of the study: 1980–2002
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: N/S
Inclusion age: N/S years
DCIS cases: 23.8
Year of events: 1992
Annual age-adjusted incidence rates per 100,000 (2000 U.S. female population): 23.8
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 24
Year of events: 1992
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 24
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 17
Year of events: 1993
Cumulative incidence rate per 100,000 over 1 year: 17
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 23.5
Year of events: 1993
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 23.5
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 18
Year of events: 1994
Cumulative incidence rate per 100,000 over 1 year: 18
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 25
Year of events: 1994
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 25
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 18
Year of events: 1995
Cumulative incidence rate per 100,000 over 1 year: 18
Kumar, 200543
Year of the study: 1980–2002
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: N/S
Inclusion age: N/S years
DCIS cases: 28.8
Year of events: 1995
Annual age-adjusted incidence rates per 100,000 (2000 U.S. female population): 28.8
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 28.5
Year of events: 1995
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 28.5
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 25
Year of events: 1996
Cumulative incidence rate per 100,000 over 1 year: 25
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 29.5
Year of events: 1996
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 29.5
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 23
Year of events: 1997
Cumulative incidence rate per 100,000 over 1 year: 23
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 33
Year of events: 1997
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 33
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 27
Year of events: 1998
Cumulative incidence rate per 100,000 over 1 year: 27
Kumar, 200543
Year of the study: 1980–2002
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: N/S
Inclusion age: N/S years
DCIS cases: 38
Year of events: 1998
Annual age-adjusted incidence rates per 100,000 (2000 U.S. female population): 38
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 38
Year of events: 1998
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 38
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 33.5
Year of events: 1999–2001
Cumulative incidence rate per 100,000 over 2 years: 33.5
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 35
Year of events: 1999
Cumulative incidence rate per 100,000 over 1 year: 35
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 37
Year of events: 1999
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 37
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages
DCIS cases: 36
Year of events: 2000
Cumulative incidence rate per 100,000 over 1 year: 36
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 37.5
Year of events: 2000
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 37.5
Sumner, 200756
Year of the study: 1981–2001
Data source: Florida Cancer Data System
Method to diagnose DCIS: Mammography
Inclusion age: 18–103 years
DCIS cases: 23,810
Year of events: 2001
Age-adjusted Incidence rates per 100,000 standardized to the U.S. population: 27.7
Coburn, 200434
Year of the study: 1987–2001
Data source: Rhode Island Cancer Registry
Method to diagnose DCIS: Mammogram
Inclusion age: All ages years
DCIS cases: 33
Year of events: 2001
Cumulative incidence rate per 100,000 over 1 year: 33
Kumar, 200543
Year of the study: 1980–2002
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: N/S
Inclusion age: N/S years
DCIS cases: 37.8
Year of events: 2001
Annual age-adjusted incidence rates per 100,000 (2000 U.S. female population): 37.8
Li, 200544
Year of the study: 1980–2001
Data source: 9 SEER registries in Connecticut, Hawaii, Iowa, New Mexico, and Utah and in the metropolitan areas of Atlanta, Detroit, San Francisco-Oakland, and Seattle-Puget Sound
Method to diagnose DCIS: Individual patient records
Inclusion age: ≥30 years
DCIS cases: 37.5
Year of events: 2001
Cumulative incidence per 100,000 women for 1 year age- adjusted to the 2000 U.S. population: 37.5
SEER registry data with the same time periods as Li, 200544
Baxter, 200433
Year of the study: 1992–1999
Data source: SEER Registry (11 population-based cancer registries and 3 supplemental registries that were added to SEER in January 1992)
Method to diagnose DCIS: N/S
Inclusion age: >18 years
DCIS cases: 18
Year of events: 1992
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 18
Method to diagnose DCIS: N/S
Inclusion age: >18 years
DCIS cases: 17.5
Year of events: 1993
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 17.5
Method to diagnose DCIS: N/S
Inclusion age: >18 years
DCIS cases: 19
Year of events: 1994
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 19
Method to diagnose DCIS: N/S
Inclusion age: >18 years
DCIS cases: 21.5
Year of events: 1995
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 21.5
Method to diagnose DCIS: N/S
Inclusion age: >18 years
DCIS cases: 22
Year of events: 1996
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 22
Method to diagnose DCIS: N/S
Inclusion age: >18 years DCIS cases: 25
Year of events: 1997
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 25
Method to diagnose DCIS: N/S
Inclusion age: >18 years
DCIS cases: 27.5
Year of events: 1998
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 27.5
Method to diagnose DCIS: N/S
Inclusion age: >18 years
DCIS cases: 28
Year of events: 1999
Age-adjusted annual incidence per 100,000 women (2000 U.S. Census): 28

From: Appendix F, Evidence Tables

Cover of Diagnosis and Management of Ductal Carcinoma in Situ (DCIS)
Diagnosis and Management of Ductal Carcinoma in Situ (DCIS).
Evidence Reports/Technology Assessments, No. 185.
Virnig BA, Shamliyan T, Tuttle TM, et al.

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