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Which airway device (ProSeal or Classic laryngeal airway mask) provides more effective artificial breathing during anaesthesia for adults?

We wanted to find out if one type of artificial breathing device used in adults during anaesthesia is more effective and safer than another.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Opioids for cancer‐related pain in children and adolescents

There is no evidence from randomised controlled trials to support or contradict the suggestion that opioids in any dose will reduce cancer‐related pain in children or adolescents.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Electrical stimulation through implanted electrodes in contact with the brain to treat drug‐resistant epilepsy

Despite many antiepileptic drugs being available, about 30% of epilepsy patients are not seizure‐free. Electrical stimulation through implanted electrodes in contact with the brain (i.e. intracranial electrical stimulation, referring to 'deep brain stimulation' and 'cortical brain stimulation') has been proposed as an alternative treatment for these patients. This review aimed to evaluate its efficacy, safety and tolerability.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Saline irrigation for the management of skin extravasation injury in neonates

Background: Preterm and sick term infants requiring intravenous fluids and medications are vulnerable to tissue injury secondary to extravasation, that is, leakage of fluid into surrounding tissue. Such injury can result in scarring with consequent cosmetic issues and, in some infants, functional limitations. Remedial surgical intervention may be required for some babies. Saline flush, with or without prior infiltration of hyaluronidase (a protein that promotes the breakdown of barriers that hold tissue planes together), is widely used for the management of severe extravasation injury in neonates, and is intended to prevent or reduce complications following extravasation. Conservative treatment with normal wound care and various topical dressings is commonly used at different stages of extravasation injury with variable results.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Felbamate as an add‐on therapy for refractory partial epilepsy

This review aimed to assess whether felbamate has an impact on people with refractory partial‐onset epilepsy when used with other antiepileptic drugs.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

Occupational therapy for adults with problems in activities of daily living after stroke

Different parts of the brain carry out different functions: seeing, sensation, balance, movement, understanding language, behaviour, problem solving, and emotion. A stroke occurs when the blood supply to part of the brain is cut off. If the blood supply is cut off to a part of the brain that carries out a particular function (such as seeing, moving arms and legs, or speaking), then these body parts or body functions will not work as they should.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2017

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