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Treatment of Kaposi sarcoma in children with HIV‐1 infection

Using ART and chemotherapy together increases the likelihood of KS remission and reduces the risk of death in HIV‐infected children diagnosed with KS. We found four observational studies that examined this question. Overall, we found that, though data are sparse and not adequately statistically adjusted, ART and chemotherapy together compared to chemotherapy alone and ART and chemotherapy compared to ART alone increases the likelihood of KS remission and reduces the risk of death in HIV‐infected children diagnosed with KS. The quality of this evidence is, however, weak. Future clinical trials of KS treatment options in HIV‐infected children are needed.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2014

Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults

Kaposi’s sarcoma was the first tumor to be described in association with HIV infection and is an AIDS‐defining condition. It is also known as Kaposi's sarcoma‐associated herpes virus (KSHV) as Herpes virus 8 (HHV8) is recognized as an essential and necessary factor in the pathogenesis of KS. Nonetheless, not all HHV‐8‐infected individuals will develop the disease. The abnormal cells of KS form purple, red, or brown patches, plaques or tumors on the skin. There is no universally accepted system for staging Kaposi's sarcoma. The most commonly used staging system for AIDS‐related KS in adults is the AIDS Clinical Trial Group (ACTG) staging.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2014

Kaposi Sarcoma Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of Kaposi sarcoma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: June 16, 2017

Cancer-Related Post-traumatic Stress (PDQ®): Patient Version

Expert-reviewed information summary about post-traumatic stress and related symptoms in cancer patients, cancer survivors, and their family members. Assessment and treatment of these symptoms are discussed.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 7, 2015

Grief, Bereavement, and Coping With Loss (PDQ®): Patient Version

Expert-reviewed report about grief, bereavement, and feelings of loss in survivors of someone who has died of cancer. Grief in children is also discussed.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: March 6, 2013

Adult Soft Tissue Sarcoma Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of adult soft tissue sarcoma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 15, 2017

What is tuberculous pleurisy and how might corticosteroids work?

Tuberculous pleurisy results from inflammation of the membrane that covers the lungs (the pleura) caused by exposure to Mycobacterium tuberculosis bacteria infecting the lungs. This results in a build up of fluid around the lung (pleural effusion) that causes pain and fever, impairs breathing, and may lead to impairment of lung function in the long term.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: March 14, 2017

A daily low dose of cotrimoxazole for preventing opportunistic infections in adults with HIV

Cotrimoxazole helps to prevent infections in adults who are HIV‐infected but may increase resistance to the drug and more trials are needed.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2009

Childhood Vascular Tumors Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of childhood vascular tumors.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: April 7, 2017

Mycosis Fungoides (Including Sézary Syndrome) Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of mycosis fungoides and the Sézary syndrome.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 11, 2017

Cardiopulmonary Syndromes (PDQ®): Patient Version

Expert-reviewed information summary about common conditions that produce chest symptoms. The cardiopulmonary syndromes addressed in this summary are cancer-related dyspnea, malignant pleural effusion, pericardial effusion, and superior vena cava syndrome.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: August 31, 2016

Skin Cancer Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of skin cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 12, 2017

AIDS-Related Lymphoma Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of AIDS-Related Lymphoma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: October 12, 2016

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