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This guideline has been developed to advise on the treatment and management of psychosis and schizophrenia in adults. The guideline recommendations have been developed by a multidisciplinary team of healthcare professionals, people with psychosis and schizophrenia, their carers and guideline methodologists after careful consideration of the best available evidence. It is intended that the guideline will be useful to clinicians and service commissioners in providing and planning highquality care for people with psychosis and schizophrenia while also emphasising the importance of the experience of care for people with psychosis and schizophrenia and their carers.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2014

Cancer-related post-traumatic stress can occur any time from diagnosis to after treatment ends. Shock, fear, helplessness, or horror can be felt by cancer patients and lead to cancer-related post-traumatic stress. Learn about the causes and ways doctors can help manage these symptoms of distress in this expert-reviewed summary.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 7, 2015

Expert-reviewed information summary about the unique issues that arise for children during their treatment for cancer, after the completion of treatment, and as adult survivors of cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: November 13, 2015

The purposes of this review are to identify the clinical evidence on group cognitive processing therapy (CPT) for adults (in particular veteran, active military, and first responder populations) with post-traumatic stress disorder (PTSD), anxiety and other mood disorders, and to examine the clinical effectiveness of group CPT for these patients.

Rapid Response Report: Summary with Critical Appraisal - Canadian Agency for Drugs and Technologies in Health.

Version: June 12, 2017

The Agency for Healthcare Research and Quality (AHRQ) is interested in leveraging new collaborative technologies to improve communications within and between various programs within its purview. To investigate some possibilities, the ECRI Institute Evidence-based Practice Center (EPC) was charged with examining the feasibility of using a wiki to support the collaborative development of evidence reports, technical briefs, and systematic reviews by AHRQ's EPCs. A wiki is “a type of Web page designed so that its content can be edited by anyone who accesses it, using a simplified markup language,” according to The Oxford English Dictionary. Wikis could serve multiple purposes in the workflow for EPCs. In addition to serving as a mechanism for reviewing draft reports, wikis could be used in earlier stages of topic refinement and report development, such as in the developmental phases of key questions, inclusion/exclusion criteria, and search strategies. The wiki could serve as a collaborative platform for general methods development and methodology-related discussions and potentially could facilitate submission of topic nominations by partner organizations and public stakeholders.

Methods Research Reports - Agency for Healthcare Research and Quality (US).

Version: September 2011

Mental, neurological and substance use (MNS) disorders are highly prevalent, accounting for a substantial burden of disease and disability globally. In order to bridge the gap between available resources and the significant need for services, the World Health Organization launched the Mental Health Gap Action Programme (mhGAP). The objective of mhGAP is to scale-up care and services using evidence-based interventions for prevention and management of priority MNS conditions. The mhGAP Intervention Guide version 1.0 for MNS disorders for non-specialist health settings was developed in 2010 as a simple technical tool to allow for integrated management of priority MNS conditions using protocols for clinical decision-making.

World Health Organization.

Version: 2016

Posttraumatic stress disorder (PTSD) is the emotional disorder most frequently associated with combat and other potentially traumatic experiences that may occur during military service. It is often chronic and may be associated with significant comorbidities and functional impairments. Current first-line PTSD therapies include trauma-focused cognitive behavioral psychotherapies, stress inoculation training, and pharmacotherapies. Complementary and alternative medicine (CAM) interventions include a range of therapies that are not considered standard to the practice of medicine in the U.S. CAM therapies are widely used by mental health consumers, including Veterans, and numerous stakeholders have expressed strong interest in fostering the evidence base for these approaches in PTSD. Thus, this evidence synthesis was requested by VA Research and Development to inform decisions on the need for research in this area.

Evidence-based Synthesis Program - Department of Veterans Affairs (US).

Version: August 2011

In this new consolidated guidelines document on HIV prevention, diagnosis, treatment and care for key populations, the World Health Organization brings together all existing guidance relevant to five key populations – men who have sex with men, people who inject drugs, people in prisons and other closed settings, sex workers and transgender people – and updates selected guidance and recommendations.

World Health Organization.

Version: 2016

This guideline has been developed to advise on the identification and management of depression in children and young people in primary, community and secondary care. The guideline recommendations have been developed by a multidisciplinary team of healthcare professionals, carers, and guideline methodologists after careful consideration of the best available evidence. It is intended that the guidelines will be useful to clinicians and service commissioners in providing and planning high-quality care for children and young people with depression while also emphasising the importance of the experience of care for patients and their families.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2005

To assist decision-makers considering acquisition or optimal implementation of point-of-care (POC) international normalized ratio (INR) technology, CADTH conducted a review of the clinical evidence and performed a health economic analysis to compare POC INR testing with standard INR laboratory testing. Based on these assessments and clinical expertise, the Health Technology Expert Review Panel (HTERP) developed the following statements to provide guidance on the use of POC INR testing devices for patients on long-term (> 3 months) OAT with warfarin or other vitamin K antagonists.

CADTH Optimal Use Report - Canadian Agency for Drugs and Technologies in Health.

Version: July 2014

Refugees and asylum seekers are defined in many ways but can be considered as those who did not make a voluntary choice to leave their country of origin and cannot return home in safety. Outcome data are limited and mostly focused on perinatal and mental health but do suggest significant levels of unmet need. This scoping review considered 72 studies where refugees and asylum seekers formed part or all of the population studied. Access to appropriate health care across the WHO European Region is very varied and is overwhelmingly shaped by legal frameworks and the regulation of the migration process. The need for improved communication with asylum seekers and coordinated action between agencies within and beyond the medical system is widely noted. Improved data to support intersectoral working to address the health care needs of asylum seekers and refugees are imperative.

Health Evidence Network Synthesis Report - WHO Regional Office for Europe.

Version: 2015

Evidence syntheses use multidisciplinary and intersectoral sources of evidence to support policy-making. The Health Evidence Network (HEN) has supported and strengthened the use of evidence in health policy-making in the WHO European Region since 2003. The HEN synthesis report series responds to public health questions by summarizing the best available global and local findings from peer-reviewed and grey literature, as well as policy options, and proposes general directions, strategies and actions for consideration. This resource has been developed to outline key approaches, methods and considerations for a HEN evidence synthesis to support the systematic and routine use of the best available evidence for decision-making relevant to the needs of public health decision-makers. It proposes approaches that hold both scientific rigour and practical applicability for individuals and institutions that perform, commission, review and/or publish evidence syntheses.

Health Evidence Network Synthesis Report - WHO Regional Office for Europe.

Version: 2017

Undocumented migrants are people within a country without the necessary documents and permits. They are considered at higher risk for health problems because of their irregular status and the consequences of economic and social marginalization. A systematic review found 122 documents that suggested policies and interventions to improve health care access and delivery for undocumented migrants. Undocumented migrants mostly have only access to emergency care across Europe, and even in the countries where they are fully entitled to health care, formal and informal barriers hinder their access. This raises concerns for both public health and migrant care. On the basis of findings, policy options are suggested regarding data collection, research, entitlement to health care, information and communication, training and intersectoral approaches.

Health Evidence Network Synthesis Report - WHO Regional Office for Europe.

Version: 2015

This report synthesizes the findings on policies and interventions to improve the access to and quality of health care provision for labour migrants in the WHO European Region. Based on a systematic literature review in MEDLINE, Embase, Applied Social Sciences Index and Abstracts (ASSIA), EconLit, Social Sciences Citation Index and a grey literature search of studies published in English between 2005 and 2015, 33 relevant studies were identified. Sixteen studies focused on specific policies or interventions for labour migrants and included information on whether they were successful, 17 studies plus two additional studies included best practice recommendations for future policy-making. The findings point at barriers other than legal ones, which prevent full health care utilization and highlight, inter alia, the role of documentation status, high socioeconomic status, health insurance, labour unions and safe working conditions. Other important factors include the necessity of an intersectoral approach among different government divisions and cross-border cooperation as potential contributors to reducing inequalities for labour migrants.

Health Evidence Network Synthesis Report - WHO Regional Office for Europe.

Version: 2015

Systematic reviews and other secondary research reports that are based on data from multiple sources, such as decision or cost-effectiveness analyses, often conclude by noting gaps in the available evidence and make recommendations for future research. Potential users of these recommendations include policy makers and funders, as well as healthcare researchers. The purpose of this project is to determine an optimal format for presenting a new type of product of the Evidence-based Practice Center (EPC) Program, the Future Research Needs documents. In particular, we address the following questions: What level of specificity is needed by various funders or researchers for a research needs document to be useful? How can one categorize and present research needs? What are the specific barriers to making a research needs document useful to researchers and funders?

Methods Future Research Needs Reports - Agency for Healthcare Research and Quality (US).

Version: June 2011

Governments across the WHO European Region need to take urgent action to address the growing public health, inequality, economic and environmental challenges in order to achieve sustainable development (meeting current needs without compromising the ability of future generations to meet their own needs) and to ensure health and well-being for present and future generations. Based on a scoping review, this report concludes that current investment policies and practices (doing business as usual) are unsustainable, with high costs to individuals, families, communities, societies, the economy and the planet. Investment in public health policies that are based on values and evidence provides effective and efficient, inclusive and innovative solutions that can drive social, economic and environmental sustainability. Investing for health and well-being is a driver and an enabler of sustainable development, and vice versa, and it empowers people to achieve the highest attainable standard of health for all.


Version: 2017

The Consolidated guidelines on HIV testing services bring together existing guidance relevant to the provision of HIV testing services (HTS) and addresses issues and elements for effective delivery of HTS that are common in a variety of settings, contexts and diverse populations.

World Health Organization.

Version: July 2015

This new guideline covers the identification and pathways to care for adults with common mental health disorders, specifically depression, generalised anxiety disorder, panic disorder, obsessive-compulsive disorder and post-traumatic stress disorder.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2011

Missed appointments are an avoidable cost and a resource inefficiency that impact on the health of the patient and treatment outcomes. Health-care services are increasingly utilising reminder systems to counter these negative effects. The study found that simple reminders or ‘reminder plus’ should be sent to all patients in the absence of any clear contraindication. Other reminder alternatives may be relevant for key groups of patients. We are developing a practice guideline to help managers to further tailor their reminder systems for their service and client groups.

Health Services and Delivery Research - NIHR Journals Library.

Version: October 2014

Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes.

National Academies Press (US).

Version: 2011

Systematic Reviews in PubMed

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Systematic Review Methods in PubMed

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