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Alcohol-Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking and Alcohol Dependence

This clinical guideline on alcohol-use disorders was commissioned by NICE and developed by the National Collaborating Centre for Mental Health, and sets out the evidence for the treatment and management of harmful drinking and alcohol dependence in adults and in young people aged 10 to 17 years.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2011
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Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model

This study found that evidence on the clinical effectiveness and cost-effectiveness of screening for mental health problems in young people who offend is currently lacking and that further feasibility trials of clinical effectiveness are needed to establish important parameters ahead of definitive trials of effectiveness in this area.

Health Technology Assessment - NIHR Journals Library.

Version: January 2015
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A systematic review of the clinical effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia

The study found that supervised person-centred care, communication skills and dementia-care mapping, as well as sensory therapy activities and structured music therapies, reduce agitation in care-home dementia residents. Health and social care costs were between £7000 and £15,000 depending on the severity of agitation. Further work is required to investigate interventions for agitation for use with people with dementia living in their own homes.

Health Technology Assessment - NIHR Journals Library.

Version: June 2014
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Registries for Evaluating Patient Outcomes: A User's Guide [Internet]. 3rd edition

This User's Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care.

Agency for Healthcare Research and Quality (US).

Version: April 2014

Generalised Anxiety Disorder in Adults: Management in Primary, Secondary and Community Care

This clinical guideline is an update of NICE’s previous guidance on generalised anxiety disorder. It was commissioned by NICE and developed by the National Collaborating Centre for Mental Health, and sets out clear evidence- and consensus-based recommendations for healthcare professionals on how to treat and manage generalised anxiety disorder in adults.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2011
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Treating depression during pregnancy and the postpartum: a preliminary meta-analysis

The authors concluded that the largest effects in women with non-psychotic depression during pregnancy, or postpartum, were seen with medication, alone or with cognitive-behavioural therapy (CBT); group therapy with CBT, educational and transactional analysis components; interpersonal psychotherapy; and CBT. Several limitations mean that these results should be interpreted with caution.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2006

Borderline Personality Disorder: Treatment and Management

The guideline on Borderline Personality Disorder, commissioned by NICE and developed by the National Collaborating Centre for Mental Health, sets out clear, evidence- and consensus-based recommendations for healthcare staff on how to treat and manage borderline personality disorder.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2009
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Interventions for Adolescents and Young Adults With Autism Spectrum Disorders [Internet]

We systematically reviewed evidence on therapies for adolescents and young adults (ages 13 to 30) with autism spectrum disorders (ASD). We focused on the outcomes, including harms and adverse effects, of interventions addressing the core symptoms of ASD; common medical and mental health comorbidities occurring with ASD; the attainment of goals toward functional/adult independence; educational and occupational/vocational attainment; quality of life; access to health and other services; and the transitioning process (i.e., process of transitioning to greater independent functioning). We also addressed the effects of interventions on family outcomes including parent distress and satisfaction with interventions.

Comparative Effectiveness Reviews - Agency for Healthcare Research and Quality (US).

Version: August 2012
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Depression: The Treatment and Management of Depression in Adults (Updated Edition)

This clinical guideline on depression is an updated edition of the previous guidance (published in 2004). It was commissioned by NICE and developed by the National Collaborating Centre for Mental Health, and sets out clear, evidence- and consensus-based recommendations for healthcare staff on how to treat and manage depression in adults.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2010
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Obsessive-Compulsive Disorder: Core Interventions in the Treatment of Obsessive-Compulsive Disorder and Body Dysmorphic Disorder

This guideline has been developed to advise on the identification, treatment and management of obsessive-compulsive disorder (OCD) and body dysmorphic disorder (BDD). Although distinct disorders, OCD and BDD share a number of common features and there is a high degree of similarity between the treatments for the two conditions. The guideline recommendations have been developed by a multidisciplinary team of healthcare professionals, people with OCD, a carer and guideline methodologists after careful consideration of the best available evidence. It is intended that the guideline will be useful to clinicians and service commissioners in providing and planning high quality care for those with OCD and BDD while also emphasising the importance of the experience of care for people with OCD, BDD, and carers.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2006
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Systematic reviews of and integrated report on the quantitative, qualitative and economic evidence base for the management of obesity in men

Study found that sex- and gender-related differences in relation to the content of weight-loss interventions should be recognised and efforts should be made to include accessible, male-friendly intervention settings and that health service staff should initiate discussion regarding weight-loss services.

Health Technology Assessment - NIHR Journals Library.

Version: May 2014
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Nonpharmacological Versus Pharmacological Treatments for Adult Patients With Major Depressive Disorder [Internet]

To compare the benefits and harms of second-generation antidepressants (SGAs), psychological, complementary and alternative medicine, and exercise treatment options as first-step interventions for adult outpatients with acute-phase major depressive disorder (MDD), and as second-step interventions for patients with MDD who did not achieve remission after a first treatment attempt with SGAs.

Comparative Effectiveness Reviews - Agency for Healthcare Research and Quality (US).

Version: December 2015
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Antisocial Behaviour and Conduct Disorders in Children and Young People: Recognition, Intervention and Management

Antisocial behaviour and conduct disorders are the most common reason for referral to child and adolescent mental health services and have a significant impact on the quality of life of children and young people and their parents and carers. Rates of other mental health problems (including antisocial personality disorder) are considerably increased for adults who had a conduct disorder in childhood. This new NICE guideline seeks to address these problems by offering advice on prevention strategies, as well as a range of psychosocial interventions.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2013
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Autism: The Management and Support of Children and Young People on the Autism Spectrum

This guideline has been developed to advise on the management and support of children and young people on the autism spectrum. The guideline recommendations have been developed by a multidisciplinary team of healthcare professionals, children and young people with autism, their carers and guideline methodologists after careful consideration of the best available evidence. It is intended that the guideline will be useful to clinicians and service commissioners in providing and planning high-quality care for children and young people with autism while also emphasising the importance of the experience of care for children and young people with autism and their carers.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: August 2013
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Children's Attachment: Attachment in Children and Young People Who Are Adopted from Care, in Care or at High Risk of Going into Care

This guideline has been developed to advise on attachment difficulties in children and young people who are adopted from care, in care or at high risk of going into care. Children’s attachment and its impact, particularly where children are looked after or for whom being adopted from care is the long-term plan for them, is poorly understood among a range of professionals. The purpose of this guideline is to help professionals ensure that children presenting with characteristics that suggest difficulties with attachment are diagnosed accurately and that their needs are addressed quickly. The guideline recommendations have been developed by a multidisciplinary team of healthcare professionals, care leavers who have had attachment difficulties, carers and guideline methodologists after careful consideration of the best available evidence. It is intended that the guideline will be useful to clinicians and service commissioners in providing and planning high-quality care for children with attachment difficulties while also emphasising the importance of the experience of care for children with attachment difficulties and their carers.

NICE Guideline - National Collaborating Centre for Mental Health (UK).

Version: November 2015
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Pregnancy and Complex Social Factors: A Model for Service Provision for Pregnant Women with Complex Social Factors

This guideline aims to: identify and describe best practice for service organisation and delivery that will improve access, acceptability and use of services; identify and describe services that encourage, overcome barriers to and facilitate the maintenance of contact throughout pregnancy; describe additional consultations with and/or support and information for women with complex social factors, and their partners and families, that should be provided during pregnancy, over and above that described in the NICE guideline ‘Antenatal care: routine care for the healthy pregnant woman’ (2008) (clinical guideline 62); identify when additional midwifery care or referral to other members of the maternity team (obstetricians and other specialists) would be appropriate, and what that additional care should be.

NICE Clinical Guidelines - National Collaborating Centre for Women's and Children's Health (UK).

Version: September 2010
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Self-Harm: Longer-Term Management

This is the first NICE guideline on the longer-term management of both single and recurrent episodes of self-harm.

NICE Clinical Guidelines - National Collaborating Centre for Mental Health (UK).

Version: 2012
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Evaluating the evidence on employee engagement and its potential benefits to NHS staff: a narrative synthesis of the literature

This review found evidence that organisational performance improves with better staff engagement, although this is not well defined or understood. Few studies relate to the health-care sector and more research is needed on what interventions work to improve staff engagement.

Health Services and Delivery Research - NIHR Journals Library.

Version: June 2015
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Outreach programmes for health improvement of Traveller Communities: a synthesis of evidence

The study found no evidence to suggest the requirement to develop Traveller-specific health services. Outreach can be used to develop the cultural sensitivity, accessibility and acceptability of mainstream services. Texting appointment reminders is unlikely to be expensive and might constitute the minimum acceptable action to facilitate access to health care. Appropriate payment for the registration of Traveller Community members by general practitioners might also improve access. Mobile clinics are associated with the highest costs reported, with little indication of their acceptability or cost-effectiveness. Evidence suggests that outreach is likely to be more effective when delivered by workers who share the recipients’ ethnicity.

Public Health Research - NIHR Journals Library.

Version: July 2014
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Mental Health Problems in People with Learning Disabilities: Prevention, Assessment and Management

The guideline makes recommendations for the prevention, identification, assessment and management of mental health problems in people with learning disabilities. It aims to:

NICE Guideline - National Guideline Alliance (UK).

Version: September 2016
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Systematic Reviews in PubMed

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