Format

Send to

Choose Destination
J Neurogenet. 2007 Jan-Jun;21(1-2):1-18.

Olfactory jump reflex habituation in Drosophila and effects of classical conditioning mutations.

Author information

1
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Abstract

Habituation is a nonassociative learning mechanism, in which an initial response toward repeated stimuli gradually wanes. This is amongst the simplest and most widespread forms of behavioral plasticity. So far, neither the underlying molecular mechanisms nor the precise neural networks of habituation are well understood. We have developed a novel paradigm to quantify habituation of the olfactory jump reflex in Drosophila. We present data demonstrating several behavioral properties of this phenomenon, generally observed in other species. We also show that the dunce and rutabaga memory mutants behave abnormally in this assay, suggesting that this assay might be used in behavioral screens for new mutants with defects in this simpler form of behavioral plasticity.

PMID:
17464794
PMCID:
PMC2409173
DOI:
10.1080/01677060701247508
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Taylor & Francis Icon for PubMed Central
Loading ...
Support Center