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Items: 1 to 20 of 21

1.

Targeting anti-apoptotic Bcl-2 by AT-101 to increase radiation efficacy: data from in vitro and clinical pharmacokinetic studies in head and neck cancer.

Zerp SF, Stoter TR, Hoebers FJ, van den Brekel MW, Dubbelman R, Kuipers GK, Lafleur MV, Slotman BJ, Verheij M.

Radiat Oncol. 2015 Jul 30;10:158. doi: 10.1186/s13014-015-0474-9.

2.

NAD⁺ depletion by APO866 in combination with radiation in a prostate cancer model, results from an in vitro and in vivo study.

Zerp SF, Vens C, Floot B, Verheij M, van Triest B.

Radiother Oncol. 2014 Feb;110(2):348-54. doi: 10.1016/j.radonc.2013.10.039. Epub 2014 Jan 8.

PMID:
24412016
3.

Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells.

Alderliesten MC, Klarenbeek JB, van der Luit AH, van Lummel M, Jones DR, Zerp S, Divecha N, Verheij M, van Blitterswijk WJ.

Biochem J. 2011 Nov 15;440(1):127-35. doi: 10.1042/BJ20110125.

PMID:
21793801
4.

AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis.

Zerp SF, Stoter R, Kuipers G, Yang D, Lippman ME, van Blitterswijk WJ, Bartelink H, Rooswinkel R, Lafleur V, Verheij M.

Radiat Oncol. 2009 Oct 23;4:47. doi: 10.1186/1748-717X-4-47.

5.

Alkylphospholipids inhibit capillary-like endothelial tube formation in vitro: antiangiogenic properties of a new class of antitumor agents.

Zerp SF, Vink SR, Ruiter GA, Koolwijk P, Peters E, van der Luit AH, de Jong D, Budde M, Bartelink H, van Blitterswijk WJ, Verheij M.

Anticancer Drugs. 2008 Jan;19(1):65-75.

PMID:
18043131
6.
7.

Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin.

Veldman RJ, Koning GA, van Hell A, Zerp S, Vink SR, Storm G, Verheij M, van Blitterswijk WJ.

J Pharmacol Exp Ther. 2005 Nov;315(2):704-10. Epub 2005 Jul 22.

PMID:
16040815
8.

In vivo imaging of radiation-induced apoptosis in follicular lymphoma patients.

Haas RL, de Jong D, Valdés Olmos RA, Hoefnagel CA, van den Heuvel I, Zerp SF, Bartelink H, Verheij M.

Int J Radiat Oncol Biol Phys. 2004 Jul 1;59(3):782-7.

PMID:
15183481
9.

N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx.

Veldman RJ, Zerp S, van Blitterswijk WJ, Verheij M.

Br J Cancer. 2004 Feb 23;90(4):917-25.

10.

Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway.

Ruiter GA, Zerp SF, Bartelink H, van Blitterswijk WJ, Verheij M.

Anticancer Drugs. 2003 Feb;14(2):167-73.

PMID:
12569304
11.
12.

Prognostic factors in transitional cell cancer of the bladder: an emerging role for Bcl-2 and p53.

Ong F, Moonen LM, Gallee MP, ten Bosch C, Zerp SF, Hart AA, Bartelink H, Verheij M.

Radiother Oncol. 2001 Nov;61(2):169-75.

PMID:
11690683
13.

Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis.

Ruiter GA, Verheij M, Zerp SF, van Blitterswijk WJ.

Int J Radiat Oncol Biol Phys. 2001 Feb 1;49(2):415-9. Review.

PMID:
11173135
14.

Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis.

Ruiter GA, Zerp SF, Bartelink H, van Blitterswijk WJ, Verheij M.

Cancer Res. 1999 May 15;59(10):2457-63.

15.

p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.

Zerp SF, van Elsas A, Peltenburg LT, Schrier PI.

Br J Cancer. 1999 Feb;79(5-6):921-6.

16.

The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis.

Verheij M, Ruiter GA, Zerp SF, van Blitterswijk WJ, Fuks Z, Haimovitz-Friedman A, Bartelink H.

Radiother Oncol. 1998 Jun;47(3):225-32. Review.

PMID:
9681884
17.

UV-induced N-ras mutations are T-cell targets in human melanoma.

van Elsas A, Scheibenbogen C, van der Minne C, Zerp SF, Keilholz U, Schrier PI.

Melanoma Res. 1997 Aug;7 Suppl 2:S107-13. Review.

PMID:
9578425
18.

Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma.

van Elsas A, Zerp SF, van der Flier S, Krüse KM, Aarnoudse C, Hayward NK, Ruiter DJ, Schrier PI.

Am J Pathol. 1996 Sep;149(3):883-93.

19.

Analysis of N-ras mutations in human cutaneous melanoma: tumor heterogeneity detected by polymerase chain reaction/single-stranded conformation polymorphism analysis.

van Elsas A, Zerp S, van der Flier S, Krüse-Wolters M, Vacca A, Ruiter DJ, Schrier P.

Recent Results Cancer Res. 1995;139:57-67.

PMID:
7597312
20.

Separate structural elements within internal transcribed spacer 1 of Saccharomyces cerevisiae precursor ribosomal RNA direct the formation of 17S and 26S rRNA.

van Nues RW, Rientjes JM, van der Sande CA, Zerp SF, Sluiter C, Venema J, Planta RJ, Raué HA.

Nucleic Acids Res. 1994 Mar 25;22(6):912-9.

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