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Items: 1 to 20 of 44

1.

HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork.

Bermudez JY, Webber HC, Patel GC, Liu X, Cheng YQ, Clark AF, Mao W.

Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3698-707. doi: 10.1167/iovs16-19446.

PMID:
27403998
2.
3.

Target engagement and drug residence time can be observed in living cells with BRET.

Robers MB, Dart ML, Woodroofe CC, Zimprich CA, Kirkland TA, Machleidt T, Kupcho KR, Levin S, Hartnett JR, Zimmerman K, Niles AL, Ohana RF, Daniels DL, Slater M, Wood MG, Cong M, Cheng YQ, Wood KV.

Nat Commun. 2015 Dec 3;6:10091. doi: 10.1038/ncomms10091.

4.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

PMID:
26284661
5.

Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer.

Xiao K, Li YP, Wang C, Ahmad S, Vu M, Kuma K, Cheng YQ, Lam KS.

Biomaterials. 2015 Oct;67:183-93. doi: 10.1016/j.biomaterials.2015.07.033.

6.

Determination of thailandepsin B in rat plasma with a LC-MS/MS method.

Cheng Z, Ding L, Zhang Y, Chen G, Chen C, Cheng YQ, Jiang H.

Bioanalysis. 2015;7(1):39-52. doi: 10.4155/bio.14.264.

PMID:
25558934
7.

Identification and characterization of the spiruchostatin biosynthetic gene cluster enable yield improvement by overexpressing a transcriptional activator.

Potharla VY, Wang C, Cheng YQ.

J Ind Microbiol Biotechnol. 2014 Sep;41(9):1457-65. doi: 10.1007/s10295-014-1474-8.

8.

The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth.

Weinlander E, Somnay Y, Harrison AD, Wang C, Cheng YQ, Jaskula-Sztul R, Yu XM, Chen H.

J Surg Res. 2014 Jul;190(1):191-7. doi: 10.1016/j.jss.2014.02.042.

9.

The structural basis of an NADP⁺-independent dithiol oxidase in FK228 biosynthesis.

Li J, Wang C, Zhang ZM, Cheng YQ, Zhou J.

Sci Rep. 2014 Feb 20;4:4145. doi: 10.1038/srep04145.

10.

Genome-guided discovery of diverse natural products from Burkholderia sp.

Liu X, Cheng YQ.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):275-84. doi: 10.1007/s10295-013-1376-1. Review.

12.

Activation of ClpP protease by ADEP antibiotics: insights from hydrogen exchange mass spectrometry.

Sowole MA, Alexopoulos JA, Cheng YQ, Ortega J, Konermann L.

J Mol Biol. 2013 Nov 15;425(22):4508-19. doi: 10.1016/j.jmb.2013.08.005.

PMID:
23948506
13.

Structural determinants stabilizing the axial channel of ClpP for substrate translocation.

Alexopoulos J, Ahsan B, Homchaudhuri L, Husain N, Cheng YQ, Ortega J.

Mol Microbiol. 2013 Oct;90(1):167-80. doi: 10.1111/mmi.12356.

14.

Inactivation of cyclic Di-GMP binding protein TDE0214 affects the motility, biofilm formation, and virulence of Treponema denticola.

Bian J, Liu X, Cheng YQ, Li C.

J Bacteriol. 2013 Sep;195(17):3897-905. doi: 10.1128/JB.00610-13.

15.

Isolation and characterization of spliceostatin B, a new analogue of FR901464, from Pseudomonas sp. No. 2663.

Liu X, Biswas S, Tang GL, Cheng YQ.

J Antibiot (Tokyo). 2013 Sep;66(9):555-8. doi: 10.1038/ja.2013.38. No abstract available.

16.

Effects of thailanstatins on glucocorticoid response in trabecular meshwork and steroid-induced glaucoma.

Jain A, Liu X, Wordinger RJ, Yorio T, Cheng YQ, Clark AF.

Invest Ophthalmol Vis Sci. 2013 May 3;54(5):3137-42. doi: 10.1167/iovs.12-11480.

17.

Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.

Liu X, Biswas S, Berg MG, Antapli CM, Xie F, Wang Q, Tang MC, Tang GL, Zhang L, Dreyfuss G, Cheng YQ.

J Nat Prod. 2013 Apr 26;76(4):685-93. doi: 10.1021/np300913h.

18.

Cyclo-(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43.

Liu XY, Wang C, Cheng YQ.

Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3182-3. doi: 10.1107/S1600536812043000.

19.

FK228 from Burkholderia thailandensis MSMB43.

Liu XY, Wang C, Cheng YQ.

Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 1;68(Pt 9):o2757-8. doi: 10.1107/S160053681203601X.

20.

Revised genome sequence of Burkholderia thailandensis MSMB43 with improved annotation.

Zhuo Y, Liu L, Wang Q, Liu X, Ren B, Liu M, Ni P, Cheng YQ, Zhang L.

J Bacteriol. 2012 Sep;194(17):4749-50. doi: 10.1128/JB.00931-12.

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