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Items: 1 to 20 of 27

1.

An iso-α-acid-rich extract from hops (Humulus lupulus) attenuates acute alcohol-induced liver steatosis in mice.

Hege M, Jung F, Sellmann C, Jin C, Ziegenhardt D, Hellerbrand C, Bergheim I.

Nutrition. 2018 Jan;45:68-75. doi: 10.1016/j.nut.2017.07.010. Epub 2017 Jul 27.

PMID:
29129239
2.

Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis.

Lv H, Liu Q, Wen Z, Feng H, Deng X, Ci X.

Redox Biol. 2017 Aug;12:311-324. doi: 10.1016/j.redox.2017.03.001. Epub 2017 Mar 2.

3.

Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release.

Xin G, Wei Z, Ji C, Zheng H, Gu J, Ma L, Huang W, Morris-Natschke SL, Yeh JL, Zhang R, Qin C, Wen L, Xing Z, Cao Y, Xia Q, Li K, Niu H, Lee KH, Huang W.

Free Radic Biol Med. 2017 Jul;108:247-257. doi: 10.1016/j.freeradbiomed.2017.02.018. Epub 2017 Feb 8.

4.

The antileishmanial activity of xanthohumol is mediated by mitochondrial inhibition.

Monzote L, Lackova A, Staniek K, Steinbauer S, Pichler G, Jäger W, Gille L.

Parasitology. 2017 May;144(6):747-759. doi: 10.1017/S0031182016002389. Epub 2016 Dec 12.

PMID:
27938439
5.

Xanthohumol Modulates Calcium Signaling in Rat Ventricular Myocytes: Possible Antiarrhythmic Properties.

Arnaiz-Cot JJ, Cleemann L, Morad M.

J Pharmacol Exp Ther. 2017 Jan;360(1):239-248. Epub 2016 Nov 4.

6.

Synthesis and antioxidant evaluation of desmethylxanthohumol analogs and their dimers.

Teng Y, Li X, Yang K, Li X, Zhang Z, Wang L, Deng Z, Song B, Yan Z, Zhang Y, Lu K, Yu P.

Eur J Med Chem. 2017 Jan 5;125:335-345. doi: 10.1016/j.ejmech.2016.09.024. Epub 2016 Sep 13.

PMID:
27688188
7.

Versatile antitumor potential of isoxanthohumol: Enhancement of paclitaxel activity in vivo.

Krajnović T, Kaluđerović GN, Wessjohann LA, Mijatović S, Maksimović-Ivanić D.

Pharmacol Res. 2016 Mar;105:62-73. doi: 10.1016/j.phrs.2016.01.011. Epub 2016 Jan 16.

PMID:
26784390
8.

Xanthohumol induces generation of reactive oxygen species and triggers apoptosis through inhibition of mitochondrial electron transfer chain complex I.

Zhang B, Chu W, Wei P, Liu Y, Wei T.

Free Radic Biol Med. 2015 Dec;89:486-97. doi: 10.1016/j.freeradbiomed.2015.09.021. Epub 2015 Oct 8.

PMID:
26453927
9.

Targeting oxidative stress to treat endometriosis.

Harlev A, Gupta S, Agarwal A.

Expert Opin Ther Targets. 2015;19(11):1447-64. doi: 10.1517/14728222.2015.1077226. Epub 2015 Aug 10. Review.

PMID:
26256952
10.

Activated AMPK boosts the Nrf2/HO-1 signaling axis--A role for the unfolded protein response.

Zimmermann K, Baldinger J, Mayerhofer B, Atanasov AG, Dirsch VM, Heiss EH.

Free Radic Biol Med. 2015 Nov;88(Pt B):417-426. doi: 10.1016/j.freeradbiomed.2015.03.030. Epub 2015 Apr 3.

11.

Xanthohumol modulates inflammation, oxidative stress, and angiogenesis in type 1 diabetic rat skin wound healing.

Costa R, Negrão R, Valente I, Castela Â, Duarte D, Guardão L, Magalhães PJ, Rodrigues JA, Guimarães JT, Gomes P, Soares R.

J Nat Prod. 2013 Nov 22;76(11):2047-53. doi: 10.1021/np4002898. Epub 2013 Nov 7.

PMID:
24200239
12.

Effect of xanthohumol and 8-prenylnaringenin on MCF-7 breast cancer cells oxidative stress and mitochondrial complexes expression.

Blanquer-Rosselló MM, Oliver J, Valle A, Roca P.

J Cell Biochem. 2013 Dec;114(12):2785-94. doi: 10.1002/jcb.24627.

PMID:
23836544
13.

A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.

Kirkwood JS, Legette LL, Miranda CL, Jiang Y, Stevens JF.

J Biol Chem. 2013 Jun 28;288(26):19000-13. doi: 10.1074/jbc.M112.445452. Epub 2013 May 14.

14.

Xanthohumol impairs human prostate cancer cell growth and invasion and diminishes the incidence and progression of advanced tumors in TRAMP mice.

Venè R, Benelli R, Minghelli S, Astigiano S, Tosetti F, Ferrari N.

Mol Med. 2012 Dec 6;18:1292-302. doi: 10.2119/molmed.2012.00174.

15.

Xanthohumol suppresses inflammatory response to warm ischemia-reperfusion induced liver injury.

Dorn C, Massinger S, Wuzik A, Heilmann J, Hellerbrand C.

Exp Mol Pathol. 2013 Feb;94(1):10-6. doi: 10.1016/j.yexmp.2012.05.003. Epub 2012 May 23.

PMID:
22634733
16.

Neuroprotective effects of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), in ischemic stroke of rats.

Yen TL, Hsu CK, Lu WJ, Hsieh CY, Hsiao G, Chou DS, Wu GJ, Sheu JR.

J Agric Food Chem. 2012 Feb 29;60(8):1937-44. doi: 10.1021/jf204909p. Epub 2012 Feb 15.

PMID:
22300539
17.

Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways.

Festa M, Capasso A, D'Acunto CW, Masullo M, Rossi AG, Pizza C, Piacente S.

J Nat Prod. 2011 Dec 27;74(12):2505-13. doi: 10.1021/np200390x. Epub 2011 Nov 23.

PMID:
22111577
18.

Xanthohumol-supplemented beer modulates angiogenesis and inflammation in a skin wound healing model. Involvement of local adipocytes.

Negrão R, Costa R, Duarte D, Gomes TT, Coelho P, Guimarães JT, Guardão L, Azevedo I, Soares R.

J Cell Biochem. 2012 Jan;113(1):100-9. doi: 10.1002/jcb.23332.

PMID:
21898537
19.

Redox active secondary metabolites.

Jacob C, Jamier V, Ba LA.

Curr Opin Chem Biol. 2011 Feb;15(1):149-55. doi: 10.1016/j.cbpa.2010.10.015. Epub 2010 Nov 4. Review.

PMID:
21115388
20.

Re-evaluation of superoxide scavenging capacity of xanthohumol.

Schempp H, Vogel S, Hückelhoven R, Heilmann J.

Free Radic Res. 2010 Dec;44(12):1435-44. doi: 10.3109/10715762.2010.515216. Epub 2010 Nov 1.

PMID:
21034356

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