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Items: 18

1.

The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10.

Seliger JM, Misuri L, Maser E, Hintzpeter J.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):607-614. doi: 10.1080/14756366.2018.1437728.

2.

Hop Phytochemicals and Their Potential Role in Metabolic Syndrome Prevention and Therapy.

Dostálek P, Karabín M, Jelínek L.

Molecules. 2017 Oct 19;22(10). pii: E1761. doi: 10.3390/molecules22101761. Review.

3.

Xanthohumol Restores Hepatic Glucolipid Metabolism Balance in Type 1 Diabetic Wistar Rats.

Lima-Fontes M, Costa R, Rodrigues I, Soares R.

J Agric Food Chem. 2017 Aug 30;65(34):7433-7439. doi: 10.1021/acs.jafc.7b02595. Epub 2017 Aug 18.

PMID:
28745504
4.

Xanthohumol and 8-prenylnaringenin ameliorate diabetic-related metabolic dysfunctions in mice.

Costa R, Rodrigues I, Guardão L, Rocha-Rodrigues S, Silva C, Magalhães J, Ferreira-de-Almeida M, Negrão R, Soares R.

J Nutr Biochem. 2017 Jul;45:39-47. doi: 10.1016/j.jnutbio.2017.03.006. Epub 2017 Apr 6.

PMID:
28431322
5.
6.

Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol and 8-prenylnaringenin: Unveiling the angiogenic paradox and metabolism interplay.

Costa R, Rodrigues I, Guardão L, Lima JQ, Sousa E, Soares R, Negrão R.

Mol Nutr Food Res. 2017 Apr;61(4). doi: 10.1002/mnfr.201600488. Epub 2017 Jan 30.

PMID:
27921359
7.

Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway.

Zhao X, Jiang K, Liang B, Huang X.

Oncol Rep. 2016 Feb;35(2):669-75. doi: 10.3892/or.2015.4455. Epub 2015 Nov 26.

8.

Drink your prevention: beverages with cancer preventive phytochemicals.

Rossi T, Gallo C, Bassani B, Canali S, Albini A, Bruno A.

Pol Arch Med Wewn. 2014;124(12):713-22. Epub 2014 Dec 6. Review.

9.

Xanthohumol, a prenylated chalcone from beer hops, acts as an α-glucosidase inhibitor in vitro.

Liu M, Yin H, Liu G, Dong J, Qian Z, Miao J.

J Agric Food Chem. 2014 Jun 18;62(24):5548-54. doi: 10.1021/jf500426z. Epub 2014 Jun 4.

PMID:
24897556
10.

Xanthohumol modulates inflammation, oxidative stress, and angiogenesis in type 1 diabetic rat skin wound healing.

Costa R, Negrão R, Valente I, Castela Â, Duarte D, Guardão L, Magalhães PJ, Rodrigues JA, Guimarães JT, Gomes P, Soares R.

J Nat Prod. 2013 Nov 22;76(11):2047-53. doi: 10.1021/np4002898. Epub 2013 Nov 7.

PMID:
24200239
11.

Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective.

Oberbauer E, Urmann C, Steffenhagen C, Bieler L, Brunner D, Furtner T, Humpel C, Bäumer B, Bandtlow C, Couillard-Despres S, Rivera FJ, Riepl H, Aigner L.

J Nutr Biochem. 2013 Nov;24(11):1953-62. doi: 10.1016/j.jnutbio.2013.06.005. Epub 2013 Sep 24.

PMID:
24070601
12.

A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.

Kirkwood JS, Legette LL, Miranda CL, Jiang Y, Stevens JF.

J Biol Chem. 2013 Jun 28;288(26):19000-13. doi: 10.1074/jbc.M112.445452. Epub 2013 May 14.

13.

Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.

Legette LL, Luna AY, Reed RL, Miranda CL, Bobe G, Proteau RR, Stevens JF.

Phytochemistry. 2013 Jul;91:236-41. doi: 10.1016/j.phytochem.2012.04.018. Epub 2012 May 27.

PMID:
22640929
14.

Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells.

Cho YS, Kim CH, Kim KY, Cheon HG.

Mol Cell Biochem. 2012 May;364(1-2):19-28. doi: 10.1007/s11010-011-1200-z. Epub 2011 Dec 28.

PMID:
22203421
15.

Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

Legette L, Ma L, Reed RL, Miranda CL, Christensen JM, Rodriguez-Proteau R, Stevens JF.

Mol Nutr Food Res. 2012 Mar;56(3):466-74. doi: 10.1002/mnfr.201100554. Epub 2011 Dec 7.

16.

Evidence for the Effects of Xanthohumol in Disrupting Angiogenic, but not Stable Vessels.

Negrão R, Incio J, Lopes R, Azevedo I, Soares R.

Int J Biomed Sci. 2007 Dec;3(4):279-86.

17.

Biological assays and genomic analysis reveal lipoic acid modulation of endothelial cell behavior and gene expression.

Larghero P, Venè R, Minghelli S, Travaini G, Morini M, Ferrari N, Pfeffer U, Noonan DM, Albini A, Benelli R.

Carcinogenesis. 2007 May;28(5):1008-20. Epub 2006 Nov 24.

PMID:
17127716

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