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Items: 1 to 20 of 35

1.

Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization.

Popłoński J, Turlej E, Sordon S, Tronina T, Bartmańska A, Wietrzyk J, Huszcza E.

Molecules. 2018 Mar 28;23(4). pii: E776. doi: 10.3390/molecules23040776.

2.

Inhibition of breast cancer cell survival by Xanthohumol via modulation of the Notch signaling pathway in vivo and in vitro.

Sun Z, Zhou C, Liu F, Zhang W, Chen J, Pan Y, Ma L, Liu Q, Du Y, Yang J, Wang Q.

Oncol Lett. 2018 Jan;15(1):908-916. doi: 10.3892/ol.2017.7434. Epub 2017 Nov 17.

3.

Effect of xanthohumol on Th1/Th2 balance in a breast cancer mouse model.

Zhang W, Pan Y, Gou P, Zhou C, Ma L, Liu Q, Du Y, Yang J, Wang Q.

Oncol Rep. 2018 Jan;39(1):280-288. doi: 10.3892/or.2017.6094. Epub 2017 Nov 13.

PMID:
29138867
4.

Xanthohumol, a Prenylated Chalcone from Hops, Inhibits the Viability and Stemness of Doxorubicin-Resistant MCF-7/ADR Cells.

Liu M, Yin H, Qian X, Dong J, Qian Z, Miao J.

Molecules. 2016 Dec 28;22(1). pii: E36. doi: 10.3390/molecules22010036.

5.

Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation.

Wang S, Dunlap TL, Howell CE, Mbachu OC, Rue EA, Phansalkar R, Chen SN, Pauli GF, Dietz BM, Bolton JL.

Chem Res Toxicol. 2016 Jul 18;29(7):1142-50. doi: 10.1021/acs.chemrestox.6b00112. Epub 2016 Jun 22.

6.

Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.

Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SN, Nikolić D, Pauli GF, van Breemen RB, Dietz BM, Bolton JL.

Chem Res Toxicol. 2015 Nov 16;28(11):2130-41. doi: 10.1021/acs.chemrestox.5b00310. Epub 2015 Nov 5.

7.

Isoxanthohumol--Biologically active hop flavonoid.

Żołnierczyk AK, Mączka WK, Grabarczyk M, Wińska K, Woźniak E, Anioł M.

Fitoterapia. 2015 Jun;103:71-82. doi: 10.1016/j.fitote.2015.03.007. Epub 2015 Mar 12.

PMID:
25771121
8.

The chemopreventive effect of the dietary compound kaempferol on the MCF-7 human breast cancer cell line is dependent on inhibition of glucose cellular uptake.

Azevedo C, Correia-Branco A, Araújo JR, Guimarães JT, Keating E, Martel F.

Nutr Cancer. 2015;67(3):504-13. doi: 10.1080/01635581.2015.1002625. Epub 2015 Feb 26.

PMID:
25719685
9.

Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions.

Yoshimaru T, Komatsu M, Tashiro E, Imoto M, Osada H, Miyoshi Y, Honda J, Sasa M, Katagiri T.

Sci Rep. 2014 Dec 8;4:7355. doi: 10.1038/srep07355.

10.

Xanthohumol inhibits cellular proliferation in a breast cancer cell line (MDA-MB231) through an intrinsic mitochondrial-dependent pathway.

Yoo YB, Park KS, Kim JB, Kang HJ, Yang JH, Lee EK, Kim HY.

Indian J Cancer. 2014 Oct-Dec;51(4):518-23. doi: 10.4103/0019-509X.175328.

11.

Hop-derived prenylflavonoids are substrates and inhibitors of the efflux transporter breast cancer resistance protein (BCRP/ABCG2).

Tan KW, Cooney J, Jensen D, Li Y, Paxton JW, Birch NP, Scheepens A.

Mol Nutr Food Res. 2014 Nov;58(11):2099-110. doi: 10.1002/mnfr.201400288. Epub 2014 Aug 6.

PMID:
25044854
12.

Effect of xanthohumol and 8-prenylnaringenin on MCF-7 breast cancer cells oxidative stress and mitochondrial complexes expression.

Blanquer-Rosselló MM, Oliver J, Valle A, Roca P.

J Cell Biochem. 2013 Dec;114(12):2785-94. doi: 10.1002/jcb.24627.

PMID:
23836544
13.

2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells.

Kim SY, Lee IS, Moon A.

Chem Biol Interact. 2013 May 25;203(3):565-72. doi: 10.1016/j.cbi.2013.03.012. Epub 2013 Apr 3.

PMID:
23562496
14.

Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo.

Dietz BM, Hagos GK, Eskra JN, Wijewickrama GT, Anderson JR, Nikolic D, Guo J, Wright B, Chen SN, Pauli GF, van Breemen RB, Bolton JL.

Mol Nutr Food Res. 2013 Jun;57(6):1055-66. doi: 10.1002/mnfr.201200534. Epub 2013 Mar 20.

15.

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis.

Viola K, Kopf S, Rarova L, Jarukamjorn K, Kretschy N, Teichmann M, Vonach C, Atanasov AG, Giessrigl B, Huttary N, Raab I, Krieger S, Strnad M, de Martin R, Saiko P, Szekeres T, Knasmüller S, Dirsch VM, Jäger W, Grusch M, Dolznig H, Mikulits W, Krupitza G.

Arch Toxicol. 2013 Jul;87(7):1301-12. doi: 10.1007/s00204-013-1028-2. Epub 2013 Mar 17.

PMID:
23503627
16.

Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro.

Tronina T, Bartmańska A, Filip-Psurska B, Wietrzyk J, Popłoński J, Huszcza E.

Bioorg Med Chem. 2013 Apr 1;21(7):2001-6. doi: 10.1016/j.bmc.2013.01.026. Epub 2013 Feb 4.

PMID:
23434138
17.

The radio-sensitizing effect of xanthohumol is mediated by STAT3 and EGFR suppression in doxorubicin-resistant MCF-7 human breast cancer cells.

Kang Y, Park MA, Heo SW, Park SY, Kang KW, Park PH, Kim JA.

Biochim Biophys Acta. 2013 Mar;1830(3):2638-48.

PMID:
23246576
18.

Xanthohumol and it's emerging anti-neoplastic effects: beyond it's role in breast carcinomas.

Kapoor S.

Mol Nutr Food Res. 2012 Dec;56(12):1760. doi: 10.1002/mnfr.201270105. No abstract available.

PMID:
23225618
19.

Prenylated chalcone xanthohumol associates with histones in breast cancer cells--a novel target identified by a monoclonal antibody.

Wyns C, van Steendam K, Vanhoecke B, Deforce D, Bracke M, Heyerick A.

Mol Nutr Food Res. 2012 Nov;56(11):1688-96. doi: 10.1002/mnfr.201200030. Epub 2012 Sep 24.

PMID:
23001824

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