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Items: 1 to 20 of 77


Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment.

Yang J, Li B, He QY.

Cell Death Dis. 2018 May 21;9(6):580. doi: 10.1038/s41419-018-0661-3.


Xanthohumol exerts protective effects in liver alterations associated with aging.

Fernández-García C, Rancan L, Paredes SD, Montero C, de la Fuente M, Vara E, Tresguerres JAF.

Eur J Nutr. 2018 Mar 13. doi: 10.1007/s00394-018-1657-6. [Epub ahead of print]


Inhibition of breast cancer cell survival by Xanthohumol via modulation of the Notch signaling pathway in vivo and in vitro.

Sun Z, Zhou C, Liu F, Zhang W, Chen J, Pan Y, Ma L, Liu Q, Du Y, Yang J, Wang Q.

Oncol Lett. 2018 Jan;15(1):908-916. doi: 10.3892/ol.2017.7434. Epub 2017 Nov 17.


Arachidonic Acid Reverses Xanthohumol-Induced Insufficiency in a Human First-Trimester Extravillous Trophoblast Cell Line (HTR-8/SVneo Cells).

Correia-Branco A, Keating E, Martel F.

Reprod Sci. 2017 Jan 1:1933719117746762. doi: 10.1177/1933719117746762. [Epub ahead of print]


Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma.

Walden D, Kunnimalaiyaan S, Sokolowski K, Clark TG, Kunnimalaiyaan M.

Oncotarget. 2017 Sep 30;8(50):88069-88078. doi: 10.18632/oncotarget.21422. eCollection 2017 Oct 20.


Protective effect of xanthohumol against age-related brain damage.

Rancán L, Paredes SD, García I, Muñoz P, García C, López de Hontanar G, de la Fuente M, Vara E, Tresguerres JAF.

J Nutr Biochem. 2017 Nov;49:133-140. doi: 10.1016/j.jnutbio.2017.07.011. Epub 2017 Jul 27.


Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues.

Nuti E, Bassani B, Camodeca C, Rosalia L, Cantelmo A, Gallo C, Baci D, Bruno A, Orlandini E, Nencetti S, Noonan DM, Albini A, Rossello A.

Eur J Med Chem. 2017 Sep 29;138:890-899. doi: 10.1016/j.ejmech.2017.07.024. Epub 2017 Jul 17.


Xanthohumol Restores Hepatic Glucolipid Metabolism Balance in Type 1 Diabetic Wistar Rats.

Lima-Fontes M, Costa R, Rodrigues I, Soares R.

J Agric Food Chem. 2017 Aug 30;65(34):7433-7439. doi: 10.1021/acs.jafc.7b02595. Epub 2017 Aug 18.


Comprehensive two-dimensional PC-3 prostate cancer cell membrane chromatography for screening anti-tumor components from Radix Sophorae flavescentis.

Wang Q, Xu J, Li X, Zhang D, Han Y, Zhang X.

J Sep Sci. 2017 Jul;40(13):2688-2693. doi: 10.1002/jssc.201700208.


Xanthohumol induces paraptosis of leukemia cells through p38 mitogen activated protein kinase signaling pathway.

Mi X, Wang C, Sun C, Chen X, Huo X, Zhang Y, Li G, Xu B, Zhang J, Xie J, Wang Z, Li J.

Oncotarget. 2017 May 9;8(19):31297-31304. doi: 10.18632/oncotarget.16185.


Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis.

Lv H, Liu Q, Wen Z, Feng H, Deng X, Ci X.

Redox Biol. 2017 Aug;12:311-324. doi: 10.1016/j.redox.2017.03.001. Epub 2017 Mar 2.


Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor.

Shikata Y, Yoshimaru T, Komatsu M, Katoh H, Sato R, Kanagaki S, Okazaki Y, Toyokuni S, Tashiro E, Ishikawa S, Katagiri T, Imoto M.

Cancer Sci. 2017 Apr;108(4):785-794. doi: 10.1111/cas.13175. Epub 2017 Apr 20.


Xanthohumol inhibits proliferation of laryngeal squamous cell carcinoma.

Li Y, Wang K, Yin S, Zheng H, Min D.

Oncol Lett. 2016 Dec;12(6):5289-5294. doi: 10.3892/ol.2016.5313. Epub 2016 Oct 25.


Xanthohumol, a Prenylated Chalcone from Hops, Inhibits the Viability and Stemness of Doxorubicin-Resistant MCF-7/ADR Cells.

Liu M, Yin H, Qian X, Dong J, Qian Z, Miao J.

Molecules. 2016 Dec 28;22(1). pii: E36. doi: 10.3390/molecules22010036.


Synthesis and antioxidant evaluation of desmethylxanthohumol analogs and their dimers.

Teng Y, Li X, Yang K, Li X, Zhang Z, Wang L, Deng Z, Song B, Yan Z, Zhang Y, Lu K, Yu P.

Eur J Med Chem. 2017 Jan 5;125:335-345. doi: 10.1016/j.ejmech.2016.09.024. Epub 2016 Sep 13.


Hop derived flavonoid xanthohumol inhibits endothelial cell functions via AMPK activation.

Gallo C, Dallaglio K, Bassani B, Rossi T, Rossello A, Noonan DM, D'Uva G, Bruno A, Albini A.

Oncotarget. 2016 Sep 13;7(37):59917-59931. doi: 10.18632/oncotarget.10990.


The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death.

Chen PH, Chang CK, Shih CM, Cheng CH, Lin CW, Lee CC, Liu AJ, Ho KH, Chen KC.

Neuropharmacology. 2016 Nov;110(Pt A):362-375. doi: 10.1016/j.neuropharm.2016.07.038. Epub 2016 Jul 31.


Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Prostate Cancer Cells after Treatment with Xanthohumol-A Natural Compound Present in Humulus lupulus L.

Kłósek M, Mertas A, Król W, Jaworska D, Szymszal J, Szliszka E.

Int J Mol Sci. 2016 Jun 22;17(6). pii: E837. doi: 10.3390/ijms17060837.


Xanthohumol inhibits the extracellular signal regulated kinase (ERK) signalling pathway and suppresses cell growth of lung adenocarcinoma cells.

Sławińska-Brych A, Zdzisińska B, Dmoszyńska-Graniczka M, Jeleniewicz W, Kurzepa J, Gagoś M, Stepulak A.

Toxicology. 2016 May 16;357-358:65-73. doi: 10.1016/j.tox.2016.06.008. Epub 2016 Jun 15.


Xanthohumol inhibits STAT3 activation pathway leading to growth suppression and apoptosis induction in human cholangiocarcinoma cells.

Dokduang H, Yongvanit P, Namwat N, Pairojkul C, Sangkhamanon S, Yageta MS, Murakami Y, Loilome W.

Oncol Rep. 2016 Apr;35(4):2065-72. doi: 10.3892/or.2016.4584. Epub 2016 Jan 21.


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