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Long-term treatment with olanzapine increases the number of Sox2 and doublecortin expressing cells in the adult subventricular zone.

Lasut B, Palasz A, Filipczyk L, Arias-Carrion O, Rojczyk E, Savchyna M, Bogus K, Worthington JJ, Krzystanek M, Wiaderkiewicz R.

CNS Neurol Disord Drug Targets. 2018 Jun 26. doi: 10.2174/1871527317666180627113544. [Epub ahead of print]


Prospective association between major depressive disorder and leukocyte telomere length over two years.

Vance MC, Bui E, Hoeppner SS, Kovachy B, Prescott J, Mischoulon D, Walton ZE, Dong M, Nadal MF, Worthington JJ, Hoge EA, Cassano P, Orr EH, Fava M, de Vivo I, Wong KK, Simon NM.

Psychoneuroendocrinology. 2018 Apr;90:157-164. doi: 10.1016/j.psyneuen.2018.02.015. Epub 2018 Feb 21.


Effect of long-term treatment with classical neuroleptics on NPQ/spexin, kisspeptin and POMC mRNA expression in the male rat amygdala.

Pałasz A, Pałka M, Filipczyk Ł, Menezes IC, Rojczyk E, Worthington JJ, Piwowarczyk-Nowak A, Krzystanek M, Wiaderkiewicz R.

J Neural Transm (Vienna). 2018 Jul;125(7):1099-1105. doi: 10.1007/s00702-018-1868-2. Epub 2018 Feb 27.


Medication disposal practices: Increasing patient and clinician education on safe methods.

Kinrys G, Gold AK, Worthington JJ, Nierenberg AA.

J Int Med Res. 2018 Mar;46(3):927-939. doi: 10.1177/0300060517738681. Epub 2018 Jan 11.


The potential role of the novel hypothalamic neuropeptides nesfatin-1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa.

Pałasz A, Janas-Kozik M, Borrow A, Arias-Carrión O, Worthington JJ.

Neurochem Int. 2018 Feb;113:120-136. doi: 10.1016/j.neuint.2017.12.006. Epub 2017 Dec 15. Review.


Tuft Cells: A New Flavor in Innate Epithelial Immunity.

Grencis RK, Worthington JJ.

Trends Parasitol. 2016 Aug;32(8):583-585. doi: 10.1016/ Epub 2016 May 5.


The intestinal immunoendocrine axis: novel cross-talk between enteroendocrine cells and the immune system during infection and inflammatory disease.

Worthington JJ.

Biochem Soc Trans. 2015 Aug;43(4):727-33. doi: 10.1042/BST20150090. Epub 2015 Aug 3. Review.


Long-term treatment with haloperidol affects neuropeptide S and NPSR mRNA levels in the rat brain.

Palasz A, Rojczyk E, Golyszny M, Filipczyk L, Worthington JJ, Wiaderkiewicz R.

Acta Neuropsychiatr. 2016 Apr;28(2):110-6. doi: 10.1017/neu.2015.56. Epub 2015 Oct 15.


Effects of long-term treatment with the neuroleptics haloperidol, clozapine and olanzapine on immunoexpression of NMDA receptor subunits NR1, NR2A and NR2B in the rat hippocampus.

Krzystanek M, Bogus K, Pałasz A, Krzystanek E, Worthington JJ, Wiaderkiewicz R.

Pharmacol Rep. 2015 Oct;67(5):965-9. doi: 10.1016/j.pharep.2015.01.017. Epub 2015 Feb 14.


Effector Tregs: middle-men in TGFβ activation.

Worthington JJ, Travis MA.

Oncotarget. 2015 Aug 21;6(24):19958-9. No abstract available.


Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation.

Worthington JJ, Kelly A, Smedley C, Bauché D, Campbell S, Marie JC, Travis MA.

Immunity. 2015 May 19;42(5):903-15. doi: 10.1016/j.immuni.2015.04.012. Epub 2015 May 12.


Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance.

Houlden A, Hayes KS, Bancroft AJ, Worthington JJ, Wang P, Grencis RK, Roberts IS.

PLoS One. 2015 May 4;10(5):e0125945. doi: 10.1371/journal.pone.0125945. eCollection 2015.


The novel neuropeptide phoenixin is highly co-expressed with nesfatin-1 in the rat hypothalamus, an immunohistochemical study.

Pałasz A, Rojczyk E, Bogus K, Worthington JJ, Wiaderkiewicz R.

Neurosci Lett. 2015 Apr 10;592:17-21. doi: 10.1016/j.neulet.2015.02.060. Epub 2015 Feb 28.


Neurolight -astonishing advances in brain imaging.

Rojczyk-Gołębiewska E, Pałasz A, Worthington JJ, Markowski G, Wiaderkiewicz R.

Int J Neurosci. 2015 Feb;125(2):91-9. doi: 10.3109/00207454.2014.914511. Epub 2014 May 23. Review.


Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity.

Worthington JJ, Klementowicz JE, Rahman S, Czajkowska BI, Smedley C, Waldmann H, Sparwasser T, Grencis RK, Travis MA.

PLoS Pathog. 2013;9(10):e1003675. doi: 10.1371/journal.ppat.1003675. Epub 2013 Oct 3.


Randomized controlled trial of mindfulness meditation for generalized anxiety disorder: effects on anxiety and stress reactivity.

Hoge EA, Bui E, Marques L, Metcalf CA, Morris LK, Robinaugh DJ, Worthington JJ, Pollack MH, Simon NM.

J Clin Psychiatry. 2013 Aug;74(8):786-92. doi: 10.4088/JCP.12m08083.


Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion.

Worthington JJ, Samuelson LC, Grencis RK, McLaughlin JT.

PLoS Pathog. 2013 Jan;9(1):e1003122. doi: 10.1371/journal.ppat.1003122. Epub 2013 Jan 17.


Regulation of TGFβ in the immune system: an emerging role for integrins and dendritic cells.

Worthington JJ, Fenton TM, Czajkowska BI, Klementowicz JE, Travis MA.

Immunobiology. 2012 Dec;217(12):1259-65. doi: 10.1016/j.imbio.2012.06.009. Epub 2012 Jul 2. Review.


Anchoring the Panic Disorder Severity Scale.

Keough ME, Porter E, Kredlow MA, Worthington JJ, Hoge EA, Pollack MH, Shear MK, Simon NM.

Assessment. 2012 Jun;19(2):257-9. doi: 10.1177/1073191112436668. Epub 2012 Feb 11.


Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery.

Hoge EA, Worthington JJ, Nagurney JT, Chang Y, Kay EB, Feterowski CM, Katzman AR, Goetz JM, Rosasco ML, Lasko NB, Zusman RM, Pollack MH, Orr SP, Pitman RK.

CNS Neurosci Ther. 2012 Jan;18(1):21-7. doi: 10.1111/j.1755-5949.2010.00227.x. Epub 2011 Jan 10.


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