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Review: corneal endothelial cell derivation methods from ES/iPS cells.

Hatou S, Shimmura S.

Inflamm Regen. 2019 Oct 3;39:19. doi: 10.1186/s41232-019-0108-y. eCollection 2019. Review.


The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models.

Tam BY, Chiu K, Chung H, Bossard C, Nguyen JD, Creger E, Eastman BW, Mak CC, Ibanez M, Ghias A, Cahiwat J, Do L, Cho S, Nguyen J, Deshmukh V, Stewart J, Chen CW, Barroga C, Dellamary L, Kc SK, Phalen TJ, Cha S, Yazici Y.

Cancer Lett. 2019 Sep 24. pii: S0304-3835(19)30473-2. doi: 10.1016/j.canlet.2019.09.009. [Epub ahead of print]


Targeting Jak/Stat pathway as a therapeutic strategy against SP/CD44+ tumorigenic cells in Akt/β-catenin-driven hepatocellular carcinoma.

Toh TB, Lim JJ, Hooi L, Rashid MBMA, Chow EK.

J Hepatol. 2019 Sep 18. pii: S0168-8278(19)30547-1. doi: 10.1016/j.jhep.2019.08.035. [Epub ahead of print]


TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer.

Lee GT, Rosenfeld JA, Kim WT, Kwon YS, Palapattu G, Mehra R, Kim WJ, Kim IY.

PLoS One. 2019 Sep 19;14(9):e0213488. doi: 10.1371/journal.pone.0213488. eCollection 2019.


Icariin-loaded porous scaffolds for bone regeneration through the regulation of the coupling process of osteogenesis and osteoclastic activity.

Xie Y, Sun W, Yan F, Liu H, Deng Z, Cai L.

Int J Nanomedicine. 2019 Aug 1;14:6019-6033. doi: 10.2147/IJN.S203859. eCollection 2019.


Small-Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development.

Haerlingen B, Opitz R, Vandernoot I, Trubiroha A, Gillotay P, Giusti N, Costagliola S.

Thyroid. 2019 Oct 8. doi: 10.1089/thy.2019.0122. [Epub ahead of print]


Wnt signaling: a promising target for osteoarthritis therapy.

Wang Y, Fan X, Xing L, Tian F.

Cell Commun Signal. 2019 Aug 16;17(1):97. doi: 10.1186/s12964-019-0411-x. Review.


Targeting GATA4 for cardiac repair.

Välimäki MJ, Ruskoaho HJ.

IUBMB Life. 2019 Aug 16. doi: 10.1002/iub.2150. [Epub ahead of print] Review.


Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds.

Kawata M, Mori D, Kanke K, Hojo H, Ohba S, Chung UI, Yano F, Masaki H, Otsu M, Nakauchi H, Tanaka S, Saito T.

Stem Cell Reports. 2019 Sep 10;13(3):530-544. doi: 10.1016/j.stemcr.2019.07.012. Epub 2019 Aug 8.


Targeting cancer stem cells in drug discovery: Current state and future perspectives.

Du FY, Zhou QF, Sun WJ, Chen GL.

World J Stem Cells. 2019 Jul 26;11(7):398-420. doi: 10.4252/wjsc.v11.i7.398. Review.


The small molecule WNT/β-catenin inhibitor CWP232291 blocks the growth of castration-resistant prostate cancer by activating the endoplasmic reticulum stress pathway.

Pak S, Park S, Kim Y, Park JH, Park CH, Lee KJ, Kim CS, Ahn H.

J Exp Clin Cancer Res. 2019 Aug 6;38(1):342. doi: 10.1186/s13046-019-1342-5.


Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D).

Xu P, Ianes C, Gärtner F, Liu C, Burster T, Bakulev V, Rachidi N, Knippschild U, Bischof J.

Gene. 2019 Oct 5;715:144005. doi: 10.1016/j.gene.2019.144005. Epub 2019 Jul 31. Review.


A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep.

Li Y, Ren Y, Wang Y, Tan Y, Wang Q, Cai J, Zhou J, Yang C, Zhao K, Yi K, Jin W, Wang L, Liu M, Yang J, Li M, Kang C.

Theranostics. 2019 Jun 24;9(16):4608-4623. doi: 10.7150/thno.35188. eCollection 2019.


Roads to the Fountain of Youth? Rejuvenating Intestinal Stem Cells.

Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2019 Aug;22(4):342-347. doi: 10.1089/rej.2019.2251.


The novel small molecule SR18662 efficiently inhibits the growth of colorectal cancer in vitro and in vivo.

Kim J, Wang C, Ruiz de Sabando A, Cole HL, Huang TJ, Yang J, Bannister TD, Yang VW, Bialkowska AB.

Mol Cancer Ther. 2019 Jul 29. pii: molcanther.1366.2019. doi: 10.1158/1535-7163.MCT-18-1366. [Epub ahead of print]


Small molecules re-establish neural cell fate of human fibroblasts via autophagy activation.

Rujanapun N, Heebkaew N, Promjantuek W, Sotthibundhu A, Kunhorm P, Chaicharoenaudomrung N, Noisa P.

In Vitro Cell Dev Biol Anim. 2019 Sep;55(8):622-632. doi: 10.1007/s11626-019-00381-0. Epub 2019 Jul 18.


Wnt/β-Catenin Signaling in Liver Cancers.

Wang W, Smits R, Hao H, He C.

Cancers (Basel). 2019 Jul 2;11(7). pii: E926. doi: 10.3390/cancers11070926. Review.


Selective Wnt/β-catenin Small-molecule Inhibitor CWP232228 Impairs Tumor Growth of Colon Cancer.

Kim JY, Park G, Krishnan M, Ha E, Chun KS.

Anticancer Res. 2019 Jul;39(7):3661-3667. doi: 10.21873/anticanres.13514.


Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture.

Branco MA, Cotovio JP, Rodrigues CAV, Vaz SH, Fernandes TG, Moreira LM, Cabral JMS, Diogo MM.

Sci Rep. 2019 Jun 25;9(1):9229. doi: 10.1038/s41598-019-45047-9.


Transcriptome Analysis of Small Molecule-Mediated Astrocyte-to-Neuron Reprogramming.

Ma NX, Yin JC, Chen G.

Front Cell Dev Biol. 2019 May 31;7:82. doi: 10.3389/fcell.2019.00082. eCollection 2019.

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