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Items: 1 to 20 of 175

1.

Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells.

Herati RS, Muselman A, Vella L, Bengsch B, Parkhouse K, Del Alcazar D, Kotzin J, Doyle SA, Tebas P, Hensley SE, Su LF, Schmader KE, Wherry EJ.

Sci Immunol. 2017 Feb;2(8). pii: eaag2152. doi: 10.1126/sciimmunol.aag2152. Epub 2017 Feb 17.

2.

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.

Huang AC, Postow MA, Orlowski RJ, Mick R, Bengsch B, Manne S, Xu W, Harmon S, Giles JR, Wenz B, Adamow M, Kuk D, Panageas KS, Carrera C, Wong P, Quagliarello F, Wubbenhorst B, D'Andrea K, Pauken KE, Herati RS, Staupe RP, Schenkel JM, McGettigan S, Kothari S, George SM, Vonderheide RH, Amaravadi RK, Karakousis GC, Schuchter LM, Xu X, Nathanson KL, Wolchok JD, Gangadhar TC, Wherry EJ.

Nature. 2017 May 4;545(7652):60-65. doi: 10.1038/nature22079. Epub 2017 Apr 10.

PMID:
28397821
3.

What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? Consideration of Strategies to Improve the Value of Animal Models.

Herati RS, Wherry EJ.

Cold Spring Harb Perspect Biol. 2017 Mar 27. pii: a031583. doi: 10.1101/cshperspect.a031583. [Epub ahead of print]

PMID:
28348037
4.

Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns.

Bengsch B, Ohtani T, Herati RS, Bovenschen N, Chang KM, Wherry EJ.

J Immunol Methods. 2017 Mar 19. pii: S0022-1759(17)30132-1. doi: 10.1016/j.jim.2017.03.009. [Epub ahead of print]

5.

Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.

Nice TJ, Osborne LC, Tomov VT, Artis D, Wherry EJ, Virgin HW.

PLoS Pathog. 2017 Feb 17;13(2):e1006223. doi: 10.1371/journal.ppat.1006223. eCollection 2017 Feb.

6.

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade.

Benci JL, Xu B, Qiu Y, Wu TJ, Dada H, Twyman-Saint Victor C, Cucolo L, Lee DS, Pauken KE, Huang AC, Gangadhar TC, Amaravadi RK, Schuchter LM, Feldman MD, Ishwaran H, Vonderheide RH, Maity A, Wherry EJ, Minn AJ.

Cell. 2016 Dec 1;167(6):1540-1554.e12. doi: 10.1016/j.cell.2016.11.022.

PMID:
27912061
7.

Pregnancy promotes tolerance to future offspring by programming selective dysfunction in long-lived maternal T cells.

Barton BM, Xu R, Wherry EJ, Porrett PM.

J Leukoc Biol. 2017 Apr;101(4):975-987. doi: 10.1189/jlb.1A0316-135R. Epub 2016 Nov 3.

PMID:
27810945
8.

The epigenetic landscape of T cell exhaustion.

Sen DR, Kaminski J, Barnitz RA, Kurachi M, Gerdemann U, Yates KB, Tsao HW, Godec J, LaFleur MW, Brown FD, Tonnerre P, Chung RT, Tully DC, Allen TM, Frahm N, Lauer GM, Wherry EJ, Yosef N, Haining WN.

Science. 2016 Dec 2;354(6316):1165-1169. Epub 2016 Oct 27.

PMID:
27789799
9.

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.

Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ.

Science. 2016 Dec 2;354(6316):1160-1165. Epub 2016 Oct 27.

10.

Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood.

Su LF, Del Alcazar D, Stelekati E, Wherry EJ, Davis MM.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6192-E6198. Epub 2016 Sep 28.

11.

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.

Kotzin JJ, Spencer SP, McCright SJ, Kumar DBU, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CCD, Virtue AT, Zhu S, Bailis W, Stein J, Hughes C, Raj A, Wherry EJ, Goff LA, Klion AD, Rinn JL, Williams A, Flavell RA, Henao-Mejia J.

Nature. 2016 Sep 8;537(7619):239-243. doi: 10.1038/nature19346. Epub 2016 Aug 15.

12.

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.

Bengsch B, Johnson AL, Kurachi M, Odorizzi PM, Pauken KE, Attanasio J, Stelekati E, McLane LM, Paley MA, Delgoffe GM, Wherry EJ.

Immunity. 2016 Aug 16;45(2):358-73. doi: 10.1016/j.immuni.2016.07.008. Epub 2016 Aug 2.

PMID:
27496729
13.

Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection.

Barnett BE, Staupe RP, Odorizzi PM, Palko O, Tomov VT, Mahan AE, Gunn B, Chen D, Paley MA, Alter G, Reiner SL, Lauer GM, Teijaro JR, Wherry EJ.

J Immunol. 2016 Aug 15;197(4):1017-22. doi: 10.4049/jimmunol.1500368. Epub 2016 Jul 18.

PMID:
27430722
14.

Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

Naradikian MS, Myles A, Beiting DP, Roberts KJ, Dawson L, Herati RS, Bengsch B, Linderman SL, Stelekati E, Spolski R, Wherry EJ, Hunter C, Hensley SE, Leonard WJ, Cancro MP.

J Immunol. 2016 Aug 15;197(4):1023-8. doi: 10.4049/jimmunol.1600522. Epub 2016 Jul 18.

PMID:
27430719
15.

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.

Nice TJ, Osborne LC, Tomov VT, Artis D, Wherry EJ, Virgin HW.

PLoS Pathog. 2016 Jun 21;12(6):e1005684. doi: 10.1371/journal.ppat.1005684. eCollection 2016 Jun. Erratum in: PLoS Pathog. 2017 Feb 17;13(2):e1006223.

16.

Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease.

Attanasio J, Wherry EJ.

Immunity. 2016 May 17;44(5):1052-68. doi: 10.1016/j.immuni.2016.04.022. Review.

17.

Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling.

Minn AJ, Wherry EJ.

Cell. 2016 Apr 7;165(2):272-5. doi: 10.1016/j.cell.2016.03.031. Review.

18.

De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute.

Mellman I, Hubbard-Lucey VM, Tontonoz MJ, Kalos MD, Chen DS, Allison JP, Drake CG, Levitsky H, Lonberg N, van der Burg SH, Fearon DT, Wherry EJ, Lowy I, Vonderheide RH, Hwu P.

Cancer Immunol Res. 2016 Apr;4(4):279-88. doi: 10.1158/2326-6066.CIR-16-0045. Review.

19.

HIV Skews the Lineage-Defining Transcriptional Profile of Mycobacterium tuberculosis-Specific CD4+ T Cells.

Riou C, Strickland N, Soares AP, Corleis B, Kwon DS, Wherry EJ, Wilkinson RJ, Burgers WA.

J Immunol. 2016 Apr 1;196(7):3006-18. doi: 10.4049/jimmunol.1502094. Epub 2016 Feb 29.

20.

Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis.

Das R, Guan P, Sprague L, Verbist K, Tedrick P, An QA, Cheng C, Kurachi M, Levine R, Wherry EJ, Canna SW, Behrens EM, Nichols KE.

Blood. 2016 Mar 31;127(13):1666-75. doi: 10.1182/blood-2015-12-684399. Epub 2016 Jan 29.

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