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Items: 1 to 20 of 414

1.

Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy.

Medler TR, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth AM, Leyshock P, Leitenberger JJ, Kulesz-Martin M, Margolin AA, Werb Z, Coussens LM.

Cancer Cell. 2018 Oct 8;34(4):561-578.e6. doi: 10.1016/j.ccell.2018.09.003.

PMID:
30300579
2.

Roles of the immune system in cancer: from tumor initiation to metastatic progression.

Gonzalez H, Hagerling C, Werb Z.

Genes Dev. 2018 Oct 1;32(19-20):1267-1284. doi: 10.1101/gad.314617.118. Review.

PMID:
30275043
3.

Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity.

Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K.

Nat Commun. 2018 May 23;9(1):2028. doi: 10.1038/s41467-018-04334-1.

4.

Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells.

Sun Z, Wang CY, Lawson DA, Kwek S, Velozo HG, Owyong M, Lai MD, Fong L, Wilson M, Su H, Werb Z, Cooke DL.

Oncotarget. 2017 Dec 29;9(13):10945-10961. doi: 10.18632/oncotarget.23760. eCollection 2018 Feb 16.

5.

Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers.

Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z.

Genes Dev. 2018 Feb 1;32(3-4):244-257. doi: 10.1101/gad.301366.117. Epub 2018 Feb 26.

6.

HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice.

Devignes CS, Aslan Y, Brenot A, Devillers A, Schepers K, Fabre S, Chou J, Casbon AJ, Werb Z, Provot S.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E992-E1001. doi: 10.1073/pnas.1718009115. Epub 2018 Jan 16.

7.

Innate and acquired immune surveillance in the postdissemination phase of metastasis.

Gonzalez H, Robles I, Werb Z.

FEBS J. 2018 Feb;285(4):654-664. doi: 10.1111/febs.14325. Epub 2017 Nov 24. Review.

PMID:
29131550
8.

Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis.

Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z.

Transl Stroke Res. 2018 Feb;9(1):20-33. doi: 10.1007/s12975-017-0560-4. Epub 2017 Sep 13.

9.

GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis.

Shahi P, Wang CY, Chou J, Hagerling C, Gonzalez Velozo H, Ruderisch A, Yu Y, Lai MD, Werb Z.

Oncogene. 2017 Oct 5;36(40):5567-5575. doi: 10.1038/onc.2017.165. Epub 2017 Jun 5.

10.

Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling.

Kessenbrock K, Smith P, Steenbeek SC, Pervolarakis N, Kumar R, Minami Y, Goga A, Hinck L, Werb Z.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3121-3126. doi: 10.1073/pnas.1701464114. Epub 2017 Mar 7.

11.

ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression.

Shahi P, Wang CY, Lawson DA, Slorach EM, Lu A, Yu Y, Lai MD, Gonzalez Velozo H, Werb Z.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3169-3174. doi: 10.1073/pnas.1701690114. Epub 2017 Mar 3.

12.

Systematic analysis of the achaete-scute complex-like gene signature in clinical cancer patients.

Wang CY, Shahi P, Huang JT, Phan NN, Sun Z, Lin YC, Lai MD, Werb Z.

Mol Clin Oncol. 2017 Jan;6(1):7-18. doi: 10.3892/mco.2016.1094. Epub 2016 Nov 25.

13.

PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression.

Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, Corella AN, Eyob H, Kessenbrock K, Lawson DA, Marsh LA, Anderton BN, Rohrberg J, Kunder R, Bazarov AV, Yaswen P, McManus MT, Rugo HS, Werb Z, Goga A.

Nat Med. 2016 Nov;22(11):1321-1329. doi: 10.1038/nm.4213. Epub 2016 Oct 24.

14.

Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer.

Takai K, Le A, Weaver VM, Werb Z.

Oncotarget. 2016 Dec 13;7(50):82889-82901. doi: 10.18632/oncotarget.12658.

15.

Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers.

Allaoui R, Bergenfelz C, Mohlin S, Hagerling C, Salari K, Werb Z, Anderson RL, Ethier SP, Jirström K, Påhlman S, Bexell D, Tahin B, Johansson ME, Larsson C, Leandersson K.

Nat Commun. 2016 Oct 11;7:13050. doi: 10.1038/ncomms13050.

16.

SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling.

Koledova Z, Zhang X, Streuli C, Clarke RB, Klein OD, Werb Z, Lu P.

Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):E5731-40. doi: 10.1073/pnas.1611532113. Epub 2016 Sep 12.

17.

Deficiency in matrix metalloproteinase-2 results in long-term vascular instability and regression in the injured mouse spinal cord.

Trivedi A, Zhang H, Ekeledo A, Lee S, Werb Z, Plant GW, Noble-Haeusslein LJ.

Exp Neurol. 2016 Oct;284(Pt A):50-62. doi: 10.1016/j.expneurol.2016.07.018. Epub 2016 Jul 25.

18.

Metalloproteinases: a Functional Pathway for Myeloid Cells.

Chou J, Chan MF, Werb Z.

Microbiol Spectr. 2016 Apr;4(2). doi: 10.1128/microbiolspec.MCHD-0002-2015. Review.

19.

Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels.

Sun Z, Lawson DA, Sinclair E, Wang CY, Lai MD, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Werb Z, Su H, Cooke DL.

Biotechnol Rep (Amst). 2015 Sep;7:157-165. Epub 2015 Aug 1.

20.

Neutrophils: Critical components in experimental animal models of cancer.

Hagerling C, Werb Z.

Semin Immunol. 2016 Apr;28(2):197-204. doi: 10.1016/j.smim.2016.02.003. Epub 2016 Mar 11. Review.

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