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Items: 1 to 20 of 367

1.

AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington's disease.

Miniarikova J, Zimmer V, Martier R, Brouwers CC, Pythoud C, Richetin K, Rey M, Lubelski J, Evers MM, van Deventer SJ, Petry H, Déglon N, Konstantinova P.

Gene Ther. 2017 Oct;24(10):630-639. doi: 10.1038/gt.2017.71. Epub 2017 Aug 3.

2.

Molecular interactions shaping the tetraspanin web.

van Deventer SJ, Dunlock VE, van Spriel AB.

Biochem Soc Trans. 2017 Jun 15;45(3):741-750. doi: 10.1042/BST20160284. Review.

PMID:
28620035
3.

Tetraspanin microdomains control localized protein kinase C signaling in B cells.

Zuidscherwoude M, Dunlock VE, van den Bogaart G, van Deventer SJ, van der Schaaf A, van Oostrum J, Goedhart J, In 't Hout J, Hämmerling GJ, Tanaka S, Nadler A, Schultz C, Wright MD, Adjobo-Hermans MJW, van Spriel AB.

Sci Signal. 2017 May 9;10(478). pii: eaag2755. doi: 10.1126/scisignal.aag2755.

PMID:
28487417
4.

Effects of the cholesteryl ester transfer protein inhibitor, TA-8995, on cholesterol efflux capacity and high-density lipoprotein particle subclasses.

van Capelleveen JC, Kastelein JJ, Zwinderman AH, van Deventer SJ, Collins HL, Adelman SJ, Round P, Ford J, Rader DJ, Hovingh GK.

J Clin Lipidol. 2016 Sep-Oct;10(5):1137-1144.e3. doi: 10.1016/j.jacl.2016.06.006. Epub 2016 Jun 25.

PMID:
27678430
5.

Design, Characterization, and Lead Selection of Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease.

Miniarikova J, Zanella I, Huseinovic A, van der Zon T, Hanemaaijer E, Martier R, Koornneef A, Southwell AL, Hayden MR, van Deventer SJ, Petry H, Konstantinova P.

Mol Ther Nucleic Acids. 2016 Mar 22;5:e297. doi: 10.1038/mtna.2016.7.

6.

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial.

Hovingh GK, Kastelein JJ, van Deventer SJ, Round P, Ford J, Saleheen D, Rader DJ, Brewer HB, Barter PJ.

Lancet. 2015 Aug 1;386(9992):452-60. doi: 10.1016/S0140-6736(15)60158-1. Epub 2015 Jun 2.

PMID:
26047975
7.

Mir-142-3p target sequences reduce transgene-directed immunogenicity following intramuscular adeno-associated virus 1 vector-mediated gene delivery.

Majowicz A, Maczuga P, Kwikkers KL, van der Marel S, van Logtenstein R, Petry H, van Deventer SJ, Konstantinova P, Ferreira V.

J Gene Med. 2013 Jun-Jul;15(6-7):219-32. doi: 10.1002/jgm.2712.

PMID:
23658149
8.

Spatiotemporal analysis of organelle and macromolecular complex inheritance.

Menendez-Benito V, van Deventer SJ, Jimenez-Garcia V, Roy-Luzarraga M, van Leeuwen F, Neefjes J.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):175-80. doi: 10.1073/pnas.1207424110. Epub 2012 Dec 17.

9.

Murine CD4⁺CD25⁻ cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivo.

Majowicz A, van der Marel S, te Velde AA, Meijer SL, Petry H, van Deventer SJ, Ferreira V.

BMC Gastroenterol. 2012 Dec 3;12:172. doi: 10.1186/1471-230X-12-172.

10.

Adeno-associated virus mediated delivery of Tregitope 167 ameliorates experimental colitis.

van der Marel S, Majowicz A, Kwikkers K, van Logtenstein R, te Velde AA, De Groot AS, Meijer SL, van Deventer SJ, Petry H, Hommes DW, Ferreira V.

World J Gastroenterol. 2012 Aug 28;18(32):4288-99. doi: 10.3748/wjg.v18.i32.4288.

11.

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.

Borel F, Han R, Visser A, Petry H, van Deventer SJ, Jansen PL, Konstantinova P; Réseau Centre de Ressources Biologiques Foie (French Liver Biobanks Network), France.

Hepatology. 2012 Mar;55(3):821-32. doi: 10.1002/hep.24682. Epub 2012 Jan 13.

PMID:
21932399
12.

Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells.

Huibregtse IL, Zaat SA, Kapsenberg ML, Sartori da Silva MA, Peppelenbosch MP, van Deventer SJ, Braat H.

Gastroenterol Res Pract. 2012;2012:639291. doi: 10.1155/2012/639291. Epub 2011 Jul 27.

13.

In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs.

Borel F, van Logtenstein R, Koornneef A, Maczuga P, Ritsema T, Petry H, van Deventer SJ, Jansen PL, Konstantinova P.

J RNAi Gene Silencing. 2011;7:434-42. Epub 2011 Jun 17.

14.

Recombination-induced tag exchange to track old and new proteins.

Verzijlbergen KF, Menendez-Benito V, van Welsem T, van Deventer SJ, Lindstrom DL, Ovaa H, Neefjes J, Gottschling DE, van Leeuwen F.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):64-8. doi: 10.1073/pnas.0911164107. Epub 2009 Dec 14.

15.

Two Dot1 isoforms in Saccharomyces cerevisiae as a result of leaky scanning by the ribosome.

Frederiks F, Heynen GJ, van Deventer SJ, Janssen H, van Leeuwen F.

Nucleic Acids Res. 2009 Nov;37(21):7047-58. doi: 10.1093/nar/gkp765.

16.

Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic Abo Dq8 transgenic mice.

Huibregtse IL, Marietta EV, Rashtak S, Koning F, Rottiers P, David CS, van Deventer SJ, Murray JA.

J Immunol. 2009 Aug 15;183(4):2390-6. doi: 10.4049/jimmunol.0802891. Epub 2009 Jul 27.

17.

A double-blind, placebo-controlled, randomized study of infliximab in primary sclerosing cholangitis.

Hommes DW, Erkelens W, Ponsioen C, Stokkers P, Rauws E, van der Spek M, ten Kate F, van Deventer SJ.

J Clin Gastroenterol. 2008 May-Jun;42(5):522-6. doi: 10.1097/MCG.0b013e3181662426.

PMID:
18344886
18.

Alterations in lipoprotein homeostasis during human experimental endotoxemia and clinical sepsis.

Levels JH, Pajkrt D, Schultz M, Hoek FJ, van Tol A, Meijers JC, van Deventer SJ.

Biochim Biophys Acta. 2007 Dec;1771(12):1429-38. Epub 2007 Oct 12.

PMID:
17980169
19.

Muramyl dipeptide-induced differential gene expression in NOD2 mutant and wild-type Crohn's disease patient-derived dendritic cells.

Zelinkova Z, van Beelen AJ, de Kort F, Moerland PD, Ver Loren van Themaat E, te Velde AA, van Deventer SJ, de Jong EC, Hommes DW.

Inflamm Bowel Dis. 2008 Feb;14(2):186-94.

PMID:
17941075
20.

Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice.

Bleuming SA, He XC, Kodach LL, Hardwick JC, Koopman FA, Ten Kate FJ, van Deventer SJ, Hommes DW, Peppelenbosch MP, Offerhaus GJ, Li L, van den Brink GR.

Cancer Res. 2007 Sep 1;67(17):8149-55.

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