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Items: 1 to 20 of 190

1.

Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine.

Fukumoto K, Fogaça MV, Liu RJ, Duman C, Kato T, Li XY, Duman RS.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):297-302. doi: 10.1073/pnas.1814709116. Epub 2018 Dec 17.

PMID:
30559184
2.

Neuroinflammation and aberrant hippocampal plasticity in a mouse model of emotional stress evoked by exposure to ultrasound of alternating frequencies.

Pavlov D, Bettendorff L, Gorlova A, Olkhovik A, Kalueff AV, Ponomarev ED, Inozemtsev A, Chekhonin V, Lesсh KP, Anthony DC, Strekalova T.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 2;90:104-116. doi: 10.1016/j.pnpbp.2018.11.014. Epub 2018 Nov 22.

PMID:
30472146
3.

Enhancement of synaptic plasticity and reversal of impairments in motor and cognitive functions in a mouse model of Angelman Syndrome by a small neurogenic molecule, NSI-189.

Liu Y, Johe K, Sun J, Hao X, Wang Y, Bi X, Baudry M.

Neuropharmacology. 2019 Jan;144:337-344. doi: 10.1016/j.neuropharm.2018.10.038. Epub 2018 Nov 5.

PMID:
30408487
4.

Essential Role of Keap1-Nrf2 Signaling in Mood Disorders: Overview and Future Perspective.

Hashimoto K.

Front Pharmacol. 2018 Oct 16;9:1182. doi: 10.3389/fphar.2018.01182. eCollection 2018. Review.

5.

The TRKB rs2289656 genetic polymorphism is associated with acute suicide attempts in depressed patients: A transversal case control study.

Deflesselle E, Colle R, Rigal L, David DJ, Vievard A, Martin S, Becquemont L, Verstuyft C, Corruble E.

PLoS One. 2018 Oct 11;13(10):e0205648. doi: 10.1371/journal.pone.0205648. eCollection 2018.

6.

Standardized Citrus unshiu peel extract ameliorates dexamethasone-induced neurotoxicity and depressive-like behaviors in mice.

Lim DW, Um MY, Han T, Lee J, Kim YT, Cho S, Kim IH, Han D, Lee C.

Metab Brain Dis. 2018 Dec;33(6):1877-1886. doi: 10.1007/s11011-018-0294-3. Epub 2018 Sep 18.

PMID:
30229385
7.

Altered Trek-1 Function in Sortilin Deficient Mice Results in Decreased Depressive-Like Behavior.

Moreno S, Devader CM, Pietri M, Borsotto M, Heurteaux C, Mazella J.

Front Pharmacol. 2018 Aug 6;9:863. doi: 10.3389/fphar.2018.00863. eCollection 2018.

8.

Gypenosides reverses depressive behavior via inhibiting hippocampal neuroinflammation.

Dong SQ, Zhang QP, Zhu JX, Chen M, Li CF, Liu Q, Geng D, Yi LT.

Biomed Pharmacother. 2018 Oct;106:1153-1160. doi: 10.1016/j.biopha.2018.07.040. Epub 2018 Jul 18.

PMID:
30119182
9.

Role of a VGF/BDNF/TrkB Autoregulatory Feedback Loop in Rapid-Acting Antidepressant Efficacy.

Jiang C, Lin WJ, Salton SR.

J Mol Neurosci. 2018 Jul 18. doi: 10.1007/s12031-018-1124-0. [Epub ahead of print]

PMID:
30022437
10.

Minocycline ameliorates depressive behaviors and neuro-immune dysfunction induced by chronic unpredictable mild stress in the rat.

Zhang C, Zhang YP, Li YY, Liu BP, Wang HY, Li KW, Zhao S, Song C.

Behav Brain Res. 2019 Jan 1;356:348-357. doi: 10.1016/j.bbr.2018.07.001. Epub 2018 Jul 9.

PMID:
30003978
11.

Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury.

Fang X, Yang C, Li S, Zhan G, Zhang J, Huang N, Du X, Xu H, Hashimoto K, Luo A.

Eur Arch Psychiatry Clin Neurosci. 2018 Jun 7. doi: 10.1007/s00406-018-0909-z. [Epub ahead of print]

PMID:
29882089
12.

The antidepressant-like effects of Chaihu Shugan San: Dependent on the hippocampal BDNF-TrkB-ERK/Akt signaling activation in perimenopausal depression-like rats.

Chen XQ, Li CF, Chen SJ, Liang WN, Wang M, Wang SS, Dong SQ, Yi LT, Li CD.

Biomed Pharmacother. 2018 Sep;105:45-52. doi: 10.1016/j.biopha.2018.04.035. Epub 2018 May 26.

PMID:
29843044
13.

BDNF/TrkB Pathway Mediates the Antidepressant-Like Role of H2S in CUMS-Exposed Rats by Inhibition of Hippocampal ER Stress.

Wei L, Kan LY, Zeng HY, Tang YY, Huang HL, Xie M, Zou W, Wang CY, Zhang P, Tang XQ.

Neuromolecular Med. 2018 Jun;20(2):252-261. doi: 10.1007/s12017-018-8489-7. Epub 2018 Apr 27.

PMID:
29704115
14.

Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice.

Patel SS, Ray RS, Sharma A, Mehta V, Katyal A, Udayabanu M.

Metab Brain Dis. 2018 Aug;33(4):1281-1292. doi: 10.1007/s11011-018-0243-1. Epub 2018 Apr 27.

PMID:
29704081
15.

Particulate Matter Triggers Depressive-Like Response Associated With Modulation of Inflammatory Cytokine Homeostasis and Brain-Derived Neurotrophic Factor Signaling Pathway in Mice.

Liu X, Qian X, Xing J, Wang J, Sun Y, Wang Q, Li H.

Toxicol Sci. 2018 Jul 1;164(1):278-288. doi: 10.1093/toxsci/kfy086.

PMID:
29688525
16.

Silibinin exerts antidepressant effects by improving neurogenesis through BDNF/TrkB pathway.

Li YJ, Li YJ, Yang LD, Zhang K, Zheng KY, Wei XM, Yang Q, Niu WM, Zhao MG, Wu YM.

Behav Brain Res. 2018 Aug 1;348:184-191. doi: 10.1016/j.bbr.2018.04.025. Epub 2018 Apr 20.

PMID:
29680784
17.

Effectiveness of memantine on depression-like behavior, memory deficits and brain mRNA levels of BDNF and TrkB in rats subjected to repeated unpredictable stress.

Amidfar M, Kim YK, Wiborg O.

Pharmacol Rep. 2018 Jun;70(3):600-606. doi: 10.1016/j.pharep.2017.12.007. Epub 2017 Dec 20.

PMID:
29680698
18.

Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats.

Zhang YP, Wang HY, Zhang C, Liu BP, Peng ZL, Li YY, Liu FM, Song C.

Behav Brain Res. 2018 Jul 16;347:436-445. doi: 10.1016/j.bbr.2018.03.033. Epub 2018 Mar 23.

PMID:
29580890
19.

Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN.

Diniz CRAF, Casarotto PC, Fred SM, Biojone C, Castrén E, Joca SRL.

Neuropharmacology. 2018 Jun;135:163-171. doi: 10.1016/j.neuropharm.2018.03.011. Epub 2018 Mar 14.

20.

Multimodal early-life stress induces biological changes associated to psychopathologies.

Godoy LD, Umeoka EHL, Ribeiro DE, Santos VR, Antunes-Rodrigues J, Joca SRL, Garcia-Cairasco N.

Horm Behav. 2018 Apr;100:69-80. doi: 10.1016/j.yhbeh.2018.03.005. Epub 2018 Mar 20.

PMID:
29548783

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