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Items: 1 to 20 of 356

1.

Bone morphogenetic protein 9 as a key regulator of liver progenitor cells in DDC-induced cholestatic liver injury.

Addante A, Roncero C, Almalé L, Lazcanoiturburu N, García-Álvaro M, Fernández M, Sanz J, Hammad S, Nwosu ZC, Lee SJ, Fabregat I, Dooley S, Ten Dijke P, Herrera B, Sánchez A.

Liver Int. 2018 May 11. doi: 10.1111/liv.13879. [Epub ahead of print]

PMID:
29751359
2.

TGF-β family co-receptor function and signaling.

Nickel J, Ten Dijke P, Mueller TD.

Acta Biochim Biophys Sin (Shanghai). 2018 Jan 1;50(1):12-36. doi: 10.1093/abbs/gmx126.

PMID:
29293886
3.

ALK1Fc Suppresses the Human Prostate Cancer Growth in in Vitro and in Vivo Preclinical Models.

Astrologo L, Zoni E, Karkampouna S, Gray PC, Klima I, Grosjean J, Goumans MJ, Hawinkels LJAC, van der Pluijm G, Spahn M, Thalmann GN, Ten Dijke P, Kruithof-de Julio M.

Front Cell Dev Biol. 2017 Dec 5;5:104. doi: 10.3389/fcell.2017.00104. eCollection 2017.

4.

Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7.

Zhang Z, Fan Y, Xie F, Zhou H, Jin K, Shao L, Shi W, Fang P, Yang B, van Dam H, Ten Dijke P, Zheng X, Yan X, Jia J, Zheng M, Jin J, Ding C, Ye S, Zhou F, Zhang L.

Nat Commun. 2017 Dec 13;8(1):2116. doi: 10.1038/s41467-017-02029-7.

5.

JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion.

Sundqvist A, Morikawa M, Ren J, Vasilaki E, Kawasaki N, Kobayashi M, Koinuma D, Aburatani H, Miyazono K, Heldin CH, van Dam H, Ten Dijke P.

Nucleic Acids Res. 2018 Feb 16;46(3):1180-1195. doi: 10.1093/nar/gkx1190.

6.

TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases.

Pardali E, Sanchez-Duffhues G, Gomez-Puerto MC, Ten Dijke P.

Int J Mol Sci. 2017 Oct 17;18(10). pii: E2157. doi: 10.3390/ijms18102157. Review.

7.

Endothelial-to-mesenchymal transition in cardiovascular diseases: Developmental signaling pathways gone awry.

Sánchez-Duffhues G, García de Vinuesa A, Ten Dijke P.

Dev Dyn. 2018 Mar;247(3):492-508. doi: 10.1002/dvdy.24589. Epub 2017 Oct 25. Review.

PMID:
28891150
8.

Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model.

Thomsen LH, Fog-Tonnesen M, Nielsen Fink L, Norlin J, García de Vinuesa A, Hansen TK, de Heer E, Ten Dijke P, Rosendahl A.

Ren Fail. 2017 Nov;39(1):629-642. doi: 10.1080/0886022X.2017.1361837.

PMID:
28805484
9.

Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation.

Chen X, Orriols M, Walther FJ, Laghmani EH, Hoogeboom AM, Hogen-Esch ACB, Hiemstra PS, Folkerts G, Goumans MTH, Ten Dijke P, Morrell NW, Wagenaar GTM.

Front Physiol. 2017 Jul 13;8:486. doi: 10.3389/fphys.2017.00486. eCollection 2017.

10.

Targeting TGF-β Signaling in Cancer.

Colak S, Ten Dijke P.

Trends Cancer. 2017 Jan;3(1):56-71. doi: 10.1016/j.trecan.2016.11.008. Epub 2017 Jan 3. Review.

PMID:
28718426
11.

TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity.

van Caam A, Madej W, Garcia de Vinuesa A, Goumans MJ, Ten Dijke P, Blaney Davidson E, van der Kraan P.

Arthritis Res Ther. 2017 May 31;19(1):112. doi: 10.1186/s13075-017-1302-4.

12.

Erratum to: BMP type II receptor as a therapeutic target in pulmonary arterial hypertension.

Orriols M, Gomez-Puerto MC, Ten Dijke P.

Cell Mol Life Sci. 2017 Aug;74(16):2997. doi: 10.1007/s00018-017-2543-8. No abstract available.

PMID:
28536788
13.

Invasive Behavior of Human Breast Cancer Cells in Embryonic Zebrafish.

Ren J, Liu S, Cui C, Ten Dijke P.

J Vis Exp. 2017 Apr 25;(122). doi: 10.3791/55459.

PMID:
28518096
14.

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling.

Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, van Dinther M, Sixma TK, Huang H, Zhang L, Ten Dijke P.

EMBO J. 2017 Jun 1;36(11):1623-1639. doi: 10.15252/embj.201695372. Epub 2017 May 3.

15.

BMP type II receptor as a therapeutic target in pulmonary arterial hypertension.

Orriols M, Gomez-Puerto MC, Ten Dijke P.

Cell Mol Life Sci. 2017 Aug;74(16):2979-2995. doi: 10.1007/s00018-017-2510-4. Epub 2017 Apr 26. Review. Erratum in: Cell Mol Life Sci. 2017 May 23;:.

16.

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.

Xie F, Jin K, Shao L, Fan Y, Tu Y, Li Y, Yang B, van Dam H, Ten Dijke P, Weng H, Dooley S, Wang S, Jia J, Jin J, Zhou F, Zhang L.

Nat Commun. 2017 Apr 26;8:15021. doi: 10.1038/ncomms15021.

17.

Bone Morphogenetic Proteins in Vascular Homeostasis and Disease.

Goumans MJ, Zwijsen A, Ten Dijke P, Bailly S.

Cold Spring Harb Perspect Biol. 2018 Feb 1;10(2). pii: a031989. doi: 10.1101/cshperspect.a031989. Review.

PMID:
28348038
18.

TGF-β Signaling in Control of Cardiovascular Function.

Goumans MJ, Ten Dijke P.

Cold Spring Harb Perspect Biol. 2018 Feb 1;10(2). pii: a022210. doi: 10.1101/cshperspect.a022210. Review.

PMID:
28348036
19.

BMP-9 interferes with liver regeneration and promotes liver fibrosis.

Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P.

Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23.

PMID:
28336518
20.

Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2.

Kunnen SJ, Leonhard WN, Semeins C, Hawinkels LJAC, Poelma C, Ten Dijke P, Bakker A, Hierck BP, Peters DJM.

Cell Mol Life Sci. 2017 Jun;74(12):2283-2298. doi: 10.1007/s00018-017-2460-x. Epub 2017 Feb 6.

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