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Items: 1 to 20 of 31


Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study.

Yu H, Yan H, Wang L, Li J, Tan L, Deng W, Chen Q, Yang G, Zhang F, Lu T, Yang J, Li K, Lv L, Tan Q, Zhang H, Xiao X, Li M, Ma X, Yang F, Li L, Wang C, Li T, Zhang D, Yue W; Chinese Antipsychotics Pharmacogenomics Consortium.

Lancet Psychiatry. 2018 Apr;5(4):327-338. doi: 10.1016/S2215-0366(18)30049-X. Epub 2018 Mar 1.


Somatic mosaicism for SLC1A1 mutation supports threshold effect and familial aggregation in schizophrenia spectrum disorders.

Demily C, Hubert L, Franck N, Poisson A, Munnich A, Besmond C.

Schizophr Res. 2017 Nov 28. pii: S0920-9964(17)30726-0. doi: 10.1016/j.schres.2017.11.028. [Epub ahead of print] No abstract available.


Functional analysis of schizophrenia genes using GeneAnalytics program and integrated databases.

Sundararajan T, Manzardo AM, Butler MG.

Gene. 2018 Jan 30;641:25-34. doi: 10.1016/j.gene.2017.10.035. Epub 2017 Oct 13.


Reduced Slc1a1 expression is associated with neuroinflammation and impaired sensorimotor gating and cognitive performance in mice: Implications for schizophrenia.

Afshari P, Yao WD, Middleton FA.

PLoS One. 2017 Sep 8;12(9):e0183854. doi: 10.1371/journal.pone.0183854. eCollection 2017.


Characterization of a Novel Mutation in SLC1A1 Associated with Schizophrenia.

Afshari P, Myles-Worsley M, Cohen OS, Tiobech J, Faraone SV, Byerley W, Middleton FA.

Mol Neuropsychiatry. 2015 Oct;1(3):125-44. doi: 10.1159/000433599. Epub 2015 Jul 8.


Neuregulin 1 Controls Glutamate Uptake by Up-regulating Excitatory Amino Acid Carrier 1 (EAAC1).

Yu HN, Park WK, Nam KH, Song DY, Kim HS, Baik TK, Woo RS.

J Biol Chem. 2015 Aug 14;290(33):20233-44. doi: 10.1074/jbc.M114.591867. Epub 2015 Jun 19.


Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1.

Wang YN, Zhou L, Li YH, Wang Z, Li YC, Zhang YW, Wang Y, Liu G, Shen Y.

J Neurosci. 2015 Apr 22;35(16):6429-43. doi: 10.1523/JNEUROSCI.3966-14.2015.


Synergistic association of PI4KA and GRM3 genetic polymorphisms with poor antipsychotic response in south Indian schizophrenia patients with low severity of illness.

Kaur H, Jajodia A, Grover S, Baghel R, Jain S, Kukreti R.

Am J Med Genet B Neuropsychiatr Genet. 2014 Dec;165B(8):635-46. doi: 10.1002/ajmg.b.32268. Epub 2014 Sep 11.


Adult neuropsychiatric expression and familial segregation of 2q13 duplications.

Costain G, Lionel AC, Fu F, Stavropoulos DJ, Gazzellone MJ, Marshall CR, Scherer SW, Bassett AS.

Am J Med Genet B Neuropsychiatr Genet. 2014 Jun;165B(4):337-44. doi: 10.1002/ajmg.b.32236. Epub 2014 May 8.


Comorbid Obsessive-Compulsive Symptoms in Schizophrenia: Insight into Pathomechanisms Facilitates Treatment.

Zink M.

Adv Med. 2014;2014:317980. doi: 10.1155/2014/317980. Epub 2014 Jun 11. Review.


CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1.

Rees E, Walters JT, Chambert KD, O'Dushlaine C, Szatkiewicz J, Richards AL, Georgieva L, Mahoney-Davies G, Legge SE, Moran JL, Genovese G, Levinson D, Morris DW, Cormican P, Kendler KS, O'Neill FA, Riley B, Gill M, Corvin A; Wellcome Trust Case Control Consortium, Sklar P, Hultman C, Pato C, Pato M, Sullivan PF, Gejman PV, McCarroll SA, O'Donovan MC, Owen MJ, Kirov G.

Hum Mol Genet. 2014 Mar 15;23(6):1669-76. doi: 10.1093/hmg/ddt540. Epub 2013 Oct 26.


Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease.

Bianchi MG, Bardelli D, Chiu M, Bussolati O.

Cell Mol Life Sci. 2014 Jun;71(11):2001-15. doi: 10.1007/s00018-013-1484-0. Epub 2013 Oct 26. Review.


Glutamate drugs and pharmacogenetics of OCD: a pathway-based exploratory approach.

Grados MA, Specht MW, Sung HM, Fortune D.

Expert Opin Drug Discov. 2013 Dec;8(12):1515-27. doi: 10.1517/17460441.2013.845553. Epub 2013 Oct 23. Review.


Comorbid obsessive-compulsive symptoms in schizophrenia: contributions of pharmacological and genetic factors.

Schirmbeck F, Zink M.

Front Pharmacol. 2013 Aug 9;4:99. doi: 10.3389/fphar.2013.00099. eCollection 2013.


Lack of association of SLC1A1 variants with schizophrenia in Chinese Han population.

Lu W, Wu H, Cai J, Wang Z, Yi Z, Yu S, Fang Y, Zhang C.

Psychiatry Res. 2013 Dec 15;210(2):669-71. doi: 10.1016/j.psychres.2013.07.009. Epub 2013 Aug 6.


Influence of polymorphisms in genes SLC1A1, GRIN2B, and GRIK2 on clozapine-induced obsessive-compulsive symptoms.

Cai J, Zhang W, Yi Z, Lu W, Wu Z, Chen J, Yu S, Fang Y, Zhang C.

Psychopharmacology (Berl). 2013 Nov;230(1):49-55. doi: 10.1007/s00213-013-3137-2. Epub 2013 May 10.


Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia.

Shan D, Lucas EK, Drummond JB, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Schizophr Res. 2013 Mar;144(1-3):1-8. doi: 10.1016/j.schres.2012.12.019. Epub 2013 Jan 26.


Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family.

Myles-Worsley M, Tiobech J, Browning SR, Korn J, Goodman S, Gentile K, Melhem N, Byerley W, Faraone SV, Middleton FA.

Am J Med Genet B Neuropsychiatr Genet. 2013 Mar;162B(2):87-95. doi: 10.1002/ajmg.b.32125. Epub 2013 Jan 22.


Polymorphisms in the glutamate transporter gene SLC1A1 and obsessive-compulsive symptoms induced by second-generation antipsychotic agents.

Schirmbeck F, Nieratschker V, Frank J, Englisch S, Rausch F, Meyer-Lindenberg A, Rietschel M, Zink M.

Psychiatr Genet. 2012 Oct;22(5):245-52. doi: 10.1097/YPG.0b013e328353fbee.


Gene expression of glutamate transporters SLC1A1, SLC1A3 and SLC1A6 in the cerebellar subregions of elderly schizophrenia patients and effects of antipsychotic treatment.

Wilmsdorff MV, Blaich C, Zink M, Treutlein J, Bauer M, Schulze T, Schneider-Axmann T, Gruber O, Rietschel M, Schmitt A, Falkai P.

World J Biol Psychiatry. 2013 Sep;14(7):490-9. doi: 10.3109/15622975.2011.645877. Epub 2012 Mar 16.


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