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Items: 20

1.

The ER stress sensor PERK luminal domain functions as a molecular chaperone to interact with misfolded proteins.

Wang P, Li J, Sha B.

Acta Crystallogr D Struct Biol. 2016 Dec 1;72(Pt 12):1290-1297. Epub 2016 Nov 29.

2.

The structure of Tim50(164-361) suggests the mechanism by which Tim50 receives mitochondrial presequences.

Li J, Sha B.

Acta Crystallogr F Struct Biol Commun. 2015 Sep;71(Pt 9):1146-51. doi: 10.1107/S2053230X15013102. Epub 2015 Aug 25.

3.

Structural basis for the function of Tim50 in the mitochondrial presequence translocase.

Qian X, Gebert M, Höpker J, Yan M, Li J, Wiedemann N, van der Laan M, Pfanner N, Sha B.

J Mol Biol. 2011 Aug 19;411(3):513-9. doi: 10.1016/j.jmb.2011.06.020. Epub 2011 Jun 17.

4.

The structure of the PERK kinase domain suggests the mechanism for its activation.

Cui W, Li J, Ron D, Sha B.

Acta Crystallogr D Biol Crystallogr. 2011 May;67(Pt 5):423-8. doi: 10.1107/S0907444911006445. Epub 2011 Apr 13.

5.

A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway.

Zheng Y, Qin H, Frank SJ, Deng L, Litchfield DW, Tefferi A, Pardanani A, Lin FT, Li J, Sha B, Benveniste EN.

Blood. 2011 Jul 7;118(1):156-66. doi: 10.1182/blood-2010-01-266320. Epub 2011 Apr 28.

6.

The structural plasticity of Tom71 for mitochondrial precursor translocations.

Li J, Cui W, Sha B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):985-9. doi: 10.1107/S1744309110025522. Epub 2010 Aug 21.

7.

Crystal structure of P58(IPK) TPR fragment reveals the mechanism for its molecular chaperone activity in UPR.

Tao J, Petrova K, Ron D, Sha B.

J Mol Biol. 2010 Apr 16;397(5):1307-15. doi: 10.1016/j.jmb.2010.02.028. Epub 2010 Feb 22.

8.

Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.

Wen H, Li J, Song T, Lu M, Kan PY, Lee MG, Sha B, Shi X.

J Biol Chem. 2010 Mar 26;285(13):9322-6. doi: 10.1074/jbc.C109.097667. Epub 2010 Feb 2.

9.

The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion.

Hu J, Li J, Qian X, Denic V, Sha B.

PLoS One. 2009 Nov 30;4(11):e8061. doi: 10.1371/journal.pone.0008061.

10.

Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.

Li J, Qian X, Hu J, Sha B.

J Biol Chem. 2009 Aug 28;284(35):23852-9. doi: 10.1074/jbc.M109.023986. Epub 2009 Jul 6.

11.

Heat shock protein 40: structural studies and their functional implications.

Li J, Qian X, Sha B.

Protein Pept Lett. 2009;16(6):606-12. Review.

12.

Preliminary X-ray crystallographic studies of yeast Get3.

Hu J, Li J, Qian X, Jin Z, Fu Z, Sha B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 1;65(Pt 5):489-91. doi: 10.1107/S1744309109012317. Epub 2009 Apr 24.

13.

Preliminary X-ray crystallographic studies of mouse UPR responsive protein P58(IPK) TPR fragment.

Tao J, Wu Y, Ron D, Sha B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Feb 1;64(Pt 2):108-10. doi: 10.1107/S1744309108000833. Epub 2008 Jan 31.

14.

The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.

Hu J, Wu Y, Li J, Qian X, Fu Z, Sha B.

BMC Struct Biol. 2008 Jan 22;8:3. doi: 10.1186/1472-6807-8-3.

15.
16.

Preliminary X-ray crystallographic studies of yeast mitochondrial protein Tom70p.

Wu Y, McCombs D, Nagy L, DeLucas L, Sha B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Mar 1;62(Pt 3):265-7. Epub 2006 Feb 24.

17.

Preliminary crystallographic studies of yeast mitochondrial peripheral membrane protein Tim44p.

Josyula R, Jin Z, McCombs D, DeLucas L, Sha B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Feb 1;62(Pt 2):172-4. Epub 2006 Jan 27.

19.

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