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Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins.

Allen RM, Zhao S, Ramirez Solano MA, Zhu W, Michell DL, Wang Y, Shyr Y, Sethupathy P, Linton MF, Graf GA, Sheng Q, Vickers KC.

J Extracell Vesicles. 2018 Aug 13;7(1):1506198. doi: 10.1080/20013078.2018.1506198. eCollection 2018.


A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women.

Bensen JT, Graff M, Young KL, Sethupathy P, Parker J, Pecot CV, Currin K, Haddad SA, Ruiz-Narváez EA, Haiman CA, Hong CC, Sucheston-Campbell LE, Zhu Q, Liu S, Yao S, Bandera EV, Rosenberg L, Lunetta KL, Ambrosone CB, Palmer JR, Troester MA, Olshan AF.

Breast Cancer Res. 2018 Jun 5;20(1):45. doi: 10.1186/s13058-018-0964-4.


MicroRNAs in the Mammalian Gut Endocrine Lineage.

Hung YH, Sethupathy P.

Endocrinology. 2018 Feb 1;159(2):866-868. doi: 10.1210/en.2017-03117.


Adropin: An endocrine link between the biological clock and cholesterol homeostasis.

Ghoshal S, Stevens JR, Billon C, Girardet C, Sitaula S, Leon AS, Rao DC, Skinner JS, Rankinen T, Bouchard C, Nuñez MV, Stanhope KL, Howatt DA, Daugherty A, Zhang J, Schuelke M, Weiss EP, Coffey AR, Bennett BJ, Sethupathy P, Burris TP, Havel PJ, Butler AA.

Mol Metab. 2018 Feb;8:51-64. doi: 10.1016/j.molmet.2017.12.002. Epub 2017 Dec 30.


Important Considerations for Studies of Circulating MicroRNAs in Clinical Samples.

Hung YH, Sethupathy P.

EBioMedicine. 2017 Oct;24:22-23. doi: 10.1016/j.ebiom.2017.09.030. Epub 2017 Sep 23. No abstract available.


Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects.

Yan X, Wang Z, Westberg-Rasmussen S, Tarbier M, Rathjen T, Tattikota SG, Peck BCE, Kanke M, Oxvig C, Frystyk J, Starup-Linde J, Sethupathy P, Friedländer MR, Gregersen S, Poy MN.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3749-3755. doi: 10.1210/jc.2017-01365.


Systems genetics identifies a co-regulated module of liver microRNAs associated with plasma LDL cholesterol in murine diet-induced dyslipidemia.

Coffey AR, Smallwood TL, Albright J, Hua K, Kanke M, Pomp D, Bennett BJ, Sethupathy P.

Physiol Genomics. 2017 Nov 1;49(11):618-629. doi: 10.1152/physiolgenomics.00050.2017. Epub 2017 Sep 15.


Gut Microbial Influences on the Mammalian Intestinal Stem Cell Niche.

Peck BCE, Shanahan MT, Singh AP, Sethupathy P.

Stem Cells Int. 2017;2017:5604727. doi: 10.1155/2017/5604727. Epub 2017 Aug 22. Review.


Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice.

Gomez JC, Dang H, Kanke M, Hagan RS, Mock JR, Kelada SNP, Sethupathy P, Doerschuk CM.

Sci Rep. 2017 Sep 12;7(1):11258. doi: 10.1038/s41598-017-11638-7.


Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis.

Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS.

Cell Rep. 2017 Jun 6;19(10):2116-2129. doi: 10.1016/j.celrep.2017.05.032.


Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells.

Smith KN, Starmer J, Miller SC, Sethupathy P, Magnuson T.

Stem Cell Reports. 2017 Jul 11;9(1):108-121. doi: 10.1016/j.stemcr.2017.05.005. Epub 2017 Jun 1.


Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma.

Dinh TA, Vitucci EC, Wauthier E, Graham RP, Pitman WA, Oikawa T, Chen M, Silva GO, Greene KG, Torbenson MS, Reid LM, Sethupathy P.

Sci Rep. 2017 Mar 17;7:44653. doi: 10.1038/srep44653.


Arsenic Exposure and Type 2 Diabetes: MicroRNAs as Mechanistic Links?

Beck R, Styblo M, Sethupathy P.

Curr Diab Rep. 2017 Mar;17(3):18. doi: 10.1007/s11892-017-0845-8. Review.


miRquant 2.0: an Expanded Tool for Accurate Annotation and Quantification of MicroRNAs and their isomiRs from Small RNA-Sequencing Data.

Kanke M, Baran-Gale J, Villanueva J, Sethupathy P.

J Integr Bioinform. 2016 Dec 22;13(5):307. doi: 10.2390/biecoll-jib-2016-307.


Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3΄ variants.

Yamane D, Selitsky SR, Shimakami T, Li Y, Zhou M, Honda M, Sethupathy P, Lemon SM.

Nucleic Acids Res. 2017 May 5;45(8):4743-4755. doi: 10.1093/nar/gkw1332.


Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status.

Peck BC, Mah AT, Pitman WA, Ding S, Lund PK, Sethupathy P.

J Biol Chem. 2017 Feb 17;292(7):2586-2600. doi: 10.1074/jbc.M116.770099. Epub 2017 Jan 4.


An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells.

Baran-Gale J, Purvis JE, Sethupathy P.

RNA. 2016 Oct;22(10):1592-603. doi: 10.1261/rna.056895.116. Epub 2016 Aug 18.


MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice.

Irani S, Pan X, Peck BC, Iqbal J, Sethupathy P, Hussain MM.

J Biol Chem. 2016 Aug 26;291(35):18397-409. doi: 10.1074/jbc.M116.728451. Epub 2016 Jun 30.


Environmental contaminants and microRNA regulation: Transcription factors as regulators of toxicant-altered microRNA expression.

Sollome J, Martin E, Sethupathy P, Fry RC.

Toxicol Appl Pharmacol. 2016 Dec 1;312:61-66. doi: 10.1016/j.taap.2016.06.009. Epub 2016 Jun 10.


miR-30 Family Controls Proliferation and Differentiation of Intestinal Epithelial Cell Models by Directing a Broad Gene Expression Program That Includes SOX9 and the Ubiquitin Ligase Pathway.

Peck BC, Sincavage J, Feinstein S, Mah AT, Simmons JG, Lund PK, Sethupathy P.

J Biol Chem. 2016 Jul 29;291(31):15975-84. doi: 10.1074/jbc.M116.733733. Epub 2016 Jun 3.

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