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Items: 1 to 20 of 74

1.

DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia.

Keller S, Punzo D, Cuomo M, Affinito O, Coretti L, Sacchi S, Florio E, Lembo F, Carella M, Copetti M, Cocozza S, Balu DT, Errico F, Usiello A, Chiariotti L.

Sci Rep. 2018 Jul 5;8(1):10163. doi: 10.1038/s41598-018-28332-x.

2.

D-serine Measurements in Brain Slices or Other Tissue Explants.

Papouin T, Haydon PG.

Bio Protoc. 2018 Jan 20;8(2). pii: e2698. doi: 10.21769/BioProtoc.2698.

3.

The Role of Serine Racemase in the Pathophysiology of Brain Disorders.

Coyle JT, Balu DT.

Adv Pharmacol. 2018;82:35-56. doi: 10.1016/bs.apha.2017.10.002. Epub 2017 Nov 29.

PMID:
29413527
4.

The Neurobiology of d-Serine Signaling.

Wolosker H.

Adv Pharmacol. 2018;82:325-348. doi: 10.1016/bs.apha.2017.08.010. Epub 2017 Nov 8.

PMID:
29413526
5.

Competitive Inhibitors Unveil Structure/Function Relationships in Human D-Amino Acid Oxidase.

Molla G.

Front Mol Biosci. 2017 Nov 27;4:80. doi: 10.3389/fmolb.2017.00080. eCollection 2017. Review.

6.

Altered CREB Binding to Activity-Dependent Genes in Serine Racemase Deficient Mice, a Mouse Model of Schizophrenia.

Balu DT, Coyle JT.

ACS Chem Neurosci. 2017 Nov 27. doi: 10.1021/acschemneuro.7b00404. [Epub ahead of print]

PMID:
29172439
7.

N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse.

Puhl MD, Desai RI, Takagi S, Presti KT, Doyle MR, Donahue RJ, Landino SM, Bergman J, Carlezon WA Jr, Coyle JT.

Addict Biol. 2017 Nov 23. doi: 10.1111/adb.12577. [Epub ahead of print]

PMID:
29168271
8.

Human serine racemase structure/activity relationship studies provide mechanistic insight and point to position 84 as a hot spot for β-elimination function.

Nelson DL, Applegate GA, Beio ML, Graham DL, Berkowitz DB.

J Biol Chem. 2017 Aug 25;292(34):13986-14002. doi: 10.1074/jbc.M117.777904. Epub 2017 Jul 10.

PMID:
28696262
9.

Schizophrenia: Basic and Clinical.

Coyle JT.

Adv Neurobiol. 2017;15:255-280. doi: 10.1007/978-3-319-57193-5_9.

PMID:
28674984
10.

Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients.

Nuzzo T, Sacchi S, Errico F, Keller S, Palumbo O, Florio E, Punzo D, Napolitano F, Copetti M, Carella M, Chiariotti L, Bertolino A, Pollegioni L, Usiello A.

NPJ Schizophr. 2017 Apr 6;3:16. doi: 10.1038/s41537-017-0015-7. eCollection 2017.

11.

Clinical and biochemical study of d-serine metabolism among schizophrenia patients.

El-Tallawy HN, Saleem TH, El-Ebidi AM, Hassan MH, Gabra RH, Farghaly WM, Abo El-Maali N, Sherkawy HS.

Neuropsychiatr Dis Treat. 2017 Apr 10;13:1057-1063. doi: 10.2147/NDT.S126979. eCollection 2017.

12.

The inverse link between genetic risk for schizophrenia and migraine through NMDA (N-methyl-D-aspartate) receptor activation via D-serine.

Van der Auwera S, Teumer A, Hertel J, Homuth G, Völker U, Lucht MJ, Degenhardt F, Schulze T, Rietschel M, Nöthen MM, John U, Nauck M, Grabe HJ.

Eur Neuropsychopharmacol. 2016 Sep;26(9):1507-1515. doi: 10.1016/j.euroneuro.2016.03.019. Epub 2016 Jul 6.

PMID:
27394076
13.

[Association of gene polymorphisms with the susceptibility of schizophrenia in Han Chinese population].

Yu H, Zhang H, Yang Y, Li W, Zhang H, Yang G, Lü L.

Zhonghua Yi Xue Za Zhi. 2015 Dec 15;95(47):3803-7. Chinese.

PMID:
27337794
14.

The NMDA Receptor and Schizophrenia: From Pathophysiology to Treatment.

Balu DT.

Adv Pharmacol. 2016;76:351-82. doi: 10.1016/bs.apha.2016.01.006. Epub 2016 Mar 4. Review.

15.

DISC1, astrocytes and neuronal maturation: a possible mechanistic link with implications for mental disorders.

Xia M, Zhu S, Shevelkin A, Ross CA, Pletnikov M.

J Neurochem. 2016 Aug;138(4):518-24. doi: 10.1111/jnc.13663.

16.

History of the Concept of Disconnectivity in Schizophrenia.

Coyle JT, Balu DT, Puhl MD, Konopaske GT.

Harv Rev Psychiatry. 2016 Mar-Apr;24(2):80-6. doi: 10.1097/HRP.0000000000000102. Review.

17.

D-Serine and Serine Racemase Are Associated with PSD-95 and Glutamatergic Synapse Stability.

Lin H, Jacobi AA, Anderson SA, Lynch DR.

Front Cell Neurosci. 2016 Feb 25;10:34. doi: 10.3389/fncel.2016.00034. eCollection 2016.

18.

An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia.

Balu DT, Li Y, Takagi S, Presti KT, Ramikie TS, Rook JM, Jones CK, Lindsley CW, Conn PJ, Bolshakov VY, Coyle JT.

Neuropsychopharmacology. 2016 Jul;41(8):2052-61. doi: 10.1038/npp.2016.2. Epub 2016 Jan 7.

19.

d-serine levels in Alzheimer's disease: implications for novel biomarker development.

Madeira C, Lourenco MV, Vargas-Lopes C, Suemoto CK, Brandão CO, Reis T, Leite RE, Laks J, Jacob-Filho W, Pasqualucci CA, Grinberg LT, Ferreira ST, Panizzutti R.

Transl Psychiatry. 2015 May 5;5:e561. doi: 10.1038/tp.2015.52.

20.

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