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Items: 1 to 20 of 400

1.

HIF-1α is required for development of the sympathetic nervous system.

Bohuslavova R, Cerychova R, Papousek F, Olejnickova V, Bartos M, Görlach A, Kolar F, Sedmera D, Semenza GL, Pavlinkova G.

Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13414-13423. doi: 10.1073/pnas.1903510116. Epub 2019 Jun 13.

2.

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension.

Dabral S, Muecke C, Valasarajan C, Schmoranzer M, Wietelmann A, Semenza GL, Meister M, Muley T, Seeger-Nukpezah T, Samakovlis C, Weissmann N, Grimminger F, Seeger W, Savai R, Pullamsetti SS.

Nat Commun. 2019 May 13;10(1):2130. doi: 10.1038/s41467-019-10044-z.

3.

Reducing bias: accounting for the order of co-first authors.

Casadevall A, Semenza GL, Jackson S, Tomaselli G, Ahima RS.

J Clin Invest. 2019 Apr 29;129(6):2167-2168. doi: 10.1172/JCI128764. eCollection 2019 Apr 29.

4.

Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy.

Xiang L, Semenza GL.

Adv Cancer Res. 2019;141:175-212. doi: 10.1016/bs.acr.2018.11.001. Epub 2018 Dec 19.

PMID:
30691683
5.

Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization.

Xiang L, Mou J, Shao B, Wei Y, Liang H, Takano N, Semenza GL, Xie G.

Cell Death Dis. 2019 Jan 17;10(2):40. doi: 10.1038/s41419-018-1291-5.

6.

Pharmacologic Targeting of Hypoxia-Inducible Factors.

Semenza GL.

Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:379-403. doi: 10.1146/annurev-pharmtox-010818-021637.

PMID:
30625281
7.

Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature.

Jiang X, Tian W, Tu AB, Pasupneti S, Shuffle E, Dahms P, Zhang P, Cai H, Dinh TT, Liu B, Cain C, Giaccia AJ, Butcher EC, Simon MC, Semenza GL, Nicolls MR.

Circulation. 2019 Jan 22;139(4):502-517. doi: 10.1161/CIRCULATIONAHA.118.036157.

PMID:
30586708
8.

Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment.

Lan J, Lu H, Samanta D, Salman S, Lu Y, Semenza GL.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9640-E9648. doi: 10.1073/pnas.1809695115. Epub 2018 Sep 21.

9.

Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors.

Samanta D, Semenza GL.

Biochim Biophys Acta Rev Cancer. 2018 Aug;1870(1):15-22. doi: 10.1016/j.bbcan.2018.07.002. Epub 2018 Jul 11. Review.

PMID:
30006019
10.

Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment.

Lu H, Tran L, Park Y, Chen I, Lan J, Xie Y, Semenza GL.

Cancer Res. 2018 Aug 1;78(15):4191-4202. doi: 10.1158/0008-5472.CAN-18-0270. Epub 2018 Jun 7.

11.

Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration.

Bao L, Chen Y, Lai HT, Wu SY, Wang JE, Hatanpaa KJ, Raisanen JM, Fontenot M, Lega B, Chiang CM, Semenza GL, Wang Y, Luo W.

Nucleic Acids Res. 2018 Jul 27;46(13):6576-6591. doi: 10.1093/nar/gky449.

12.

Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae).

Li J, Yang Q, Bai Z, Zhou W, Semenza GL, Ge RL.

Biochem Biophys Res Commun. 2018 Jun 2;500(2):117-123. doi: 10.1016/j.bbrc.2018.03.147. Epub 2018 Apr 13.

PMID:
29626477
13.

Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells.

Samanta D, Park Y, Ni X, Li H, Zahnow CA, Gabrielson E, Pan F, Semenza GL.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1239-E1248. doi: 10.1073/pnas.1718197115. Epub 2018 Jan 24.

14.

The role of hypoxia-inducible factors in carotid body (patho) physiology.

Semenza GL, Prabhakar NR.

J Physiol. 2018 Aug;596(15):2977-2983. doi: 10.1113/JP275696. Epub 2018 Feb 12. Review.

15.

In Vitro Assays of Breast Cancer Stem Cells.

Samanta D, Semenza GL.

Methods Mol Biol. 2018;1742:237-246. doi: 10.1007/978-1-4939-7665-2_21.

PMID:
29330805
16.

Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation.

Fu C, Tyagi R, Chin AC, Rojas T, Li RJ, Guha P, Bernstein IA, Rao F, Xu R, Cha JY, Xu J, Snowman AM, Semenza GL, Snyder SH.

Circ Res. 2018 Feb 2;122(3):457-472. doi: 10.1161/CIRCRESAHA.117.311983. Epub 2017 Dec 26.

17.

DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity.

Nanduri J, Peng YJ, Wang N, Khan SA, Semenza GL, Prabhakar NR.

J Physiol. 2018 Aug;596(15):3087-3100. doi: 10.1113/JP274833. Epub 2018 Jan 4.

18.

Lack of Evidence for Vasoactive and Inflammatory Mediators in the Promotion of Macular Edema Associated with Epiretinal Membranes.

Applewhite BP, Babapoor-Farrokhran S, Poon D, Hassan SJ, Wellmann E, Ying HS, Semenza GL, Montaner S, Sodhi A.

Sci Rep. 2017 Sep 6;7(1):10608. doi: 10.1038/s41598-017-08997-6.

19.

Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of Pterygia.

Meng Q, Qin Y, Deshpande M, Kashiwabuchi F, Rodrigues M, Lu Q, Ren H, Elisseeff JH, Semenza GL, Montaner SV, Sodhi A.

Invest Ophthalmol Vis Sci. 2017 Sep 1;58(11):4514-4523. doi: 10.1167/iovs.17-21974.

20.

Epigenetic changes by DNA methylation in chronic and intermittent hypoxia.

Nanduri J, Semenza GL, Prabhakar NR.

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1096-L1100. doi: 10.1152/ajplung.00325.2017. Epub 2017 Aug 24. Review.

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