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Items: 1 to 20 of 41

1.

TPH2 polymorphisms across the spectrum of psychiatric morbidity: A systematic review and meta-analysis.

Ottenhof KW, Sild M, Lévesque ML, Ruhé HG, Booij L.

Neurosci Biobehav Rev. 2018 Sep;92:29-42. doi: 10.1016/j.neubiorev.2018.05.018. Epub 2018 May 19. Review.

PMID:
29775696
2.

Genetic association analysis of serotonin and signal transduction pathways in suicide attempters from an Italian sample of psychiatric patients.

Pompili M, Gentile G, Scassellati C, Bonvicini C, Innamorati M, Erbuto D, Montebovi F, Ducci G, Forte A, De Pisa E, Ferracuti S, Serafini G, De Luca V, Amore M, Simmaco M, Girardi P.

Neurosci Lett. 2017 Aug 24;656:94-102. doi: 10.1016/j.neulet.2017.07.020. Epub 2017 Jul 14.

PMID:
28716530
3.

Genetics of Aggression in Alzheimer's Disease (AD).

Lukiw WJ, Rogaev EI.

Front Aging Neurosci. 2017 Apr 10;9:87. doi: 10.3389/fnagi.2017.00087. eCollection 2017.

4.

GeneAnalytics Pathway Analysis and Genetic Overlap among Autism Spectrum Disorder, Bipolar Disorder and Schizophrenia.

Khanzada NS, Butler MG, Manzardo AM.

Int J Mol Sci. 2017 Feb 28;18(3). pii: E527. doi: 10.3390/ijms18030527.

5.

Effect of childhood general traumas on suicide attempt depends on TPH2 and ADARB1 variants in psychiatric patients.

Karanović J, Ivković M, Jovanović VM, Šviković S, Pantović-Stefanović M, Brkušanin M, Damjanović A, Brajušković G, Savić-Pavićević D.

J Neural Transm (Vienna). 2017 May;124(5):621-629. doi: 10.1007/s00702-017-1677-z. Epub 2017 Jan 13.

PMID:
28084537
6.

Stabilization of tryptophan hydroxylase 2 by l-phenylalanine-induced dimerization.

Tidemand KD, Christensen HE, Hoeck N, Harris P, Boesen J, Peters GH.

FEBS Open Bio. 2016 Aug 22;6(10):987-999. eCollection 2016 Oct.

7.

Lipidomic profiling of tryptophan hydroxylase 2 knockout mice reveals novel lipid biomarkers associated with serotonin deficiency.

Weng R, Shen S, Burton C, Yang L, Nie H, Tian Y, Bai Y, Liu H.

Anal Bioanal Chem. 2016 Apr;408(11):2963-73. doi: 10.1007/s00216-015-9256-3. Epub 2016 Jan 15.

PMID:
26780709
8.

Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin.

Pelosi B, Pratelli M, Migliarini S, Pacini G, Pasqualetti M.

PLoS One. 2015 Aug 20;10(8):e0136422. doi: 10.1371/journal.pone.0136422. eCollection 2015.

9.

Epistatic and gene wide effects in YWHA and aromatic amino hydroxylase genes across ADHD and other common neuropsychiatric disorders: Association with YWHAE.

Jacobsen KK, Kleppe R, Johansson S, Zayats T, Haavik J.

Am J Med Genet B Neuropsychiatr Genet. 2015 Sep;168(6):423-432. doi: 10.1002/ajmg.b.32339. Epub 2015 Jul 14.

10.

Metabolomics Approach Reveals Integrated Metabolic Network Associated with Serotonin Deficiency.

Weng R, Shen S, Tian Y, Burton C, Xu X, Liu Y, Chang C, Bai Y, Liu H.

Sci Rep. 2015 Jul 8;5:11864. doi: 10.1038/srep11864.

11.

Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis.

Andreou D, Söderman E, Axelsson T, Sedvall GC, Terenius L, Agartz I, Jönsson EG.

Behav Brain Funct. 2014 Jul 29;10:26. doi: 10.1186/1744-9081-10-26.

12.

TPH2 gene polymorphisms in the regulatory region are associated with paranoid schizophrenia in Northern Han Chinese.

Xu XM, Ding M, Pang H, Wang BJ.

Genet Mol Res. 2014 Mar 12;13(1):1497-507. doi: 10.4238/2014.March.12.1.

13.

5-HTP hypothesis of schizophrenia.

Fukuda K.

Med Hypotheses. 2014 Jan;82(1):20-3. doi: 10.1016/j.mehy.2013.10.026. Epub 2013 Nov 8.

PMID:
24280562
14.

Stimulation of 5-HT2C receptors improves cognitive deficits induced by human tryptophan hydroxylase 2 loss of function mutation.

Del'Guidice T, Lemay F, Lemasson M, Levasseur-Moreau J, Manta S, Etievant A, Escoffier G, Doré FY, Roman FS, Beaulieu JM.

Neuropsychopharmacology. 2014 Apr;39(5):1125-34. doi: 10.1038/npp.2013.313. Epub 2013 Nov 7.

15.

[Implication of 5-HT2A receptors in the genetic mechanisms of the brain 5-HT system autoregulation].

Naumenko VS, Tsybko AS, Bazovkina DV, Popova NK.

Mol Biol (Mosk). 2012 May-Jun;46(3):416-22. Russian.

PMID:
22888631
16.

Investigation of tryptophan hydroxylase 2 (TPH2) in schizophrenia and in the response to antipsychotics.

Schuhmacher A, Becker T, Rujescu D, Quednow BB, Lennertz L, Wagner M, Benninghoff J, Rietschel M, Häfner H, Franke P, Wölwer W, Gaebel W, Maier W, Mössner R.

J Psychiatr Res. 2012 Aug;46(8):1073-80. doi: 10.1016/j.jpsychires.2012.04.021. Epub 2012 May 30.

17.

Common variants in the TPH2 promoter confer susceptibility to paranoid schizophrenia.

Yi Z, Zhang C, Lu W, Song L, Liu D, Xu Y, Fang Y.

J Mol Neurosci. 2012 Jul;47(3):465-9. doi: 10.1007/s12031-012-9725-5. Epub 2012 Mar 4.

PMID:
22392150
18.

A two-stage case-control association study between the tryptophan hydroxylase 2 (TPH2) gene and schizophrenia in a Japanese population.

Watanabe Y, Egawa J, Iijima Y, Nunokawa A, Kaneko N, Shibuya M, Arinami T, Ujike H, Inada T, Iwata N, Tochigi M, Kunugi H, Itokawa M, Ozaki N, Hashimoto R, Someya T.

Schizophr Res. 2012 May;137(1-3):264-6. doi: 10.1016/j.schres.2012.01.034. Epub 2012 Feb 17. No abstract available.

PMID:
22342331
19.

Boosting serotonin in the brain: is it time to revamp the treatment of depression?

Torrente MP, Gelenberg AJ, Vrana KE.

J Psychopharmacol. 2012 May;26(5):629-35. doi: 10.1177/0269881111430744. Epub 2011 Dec 8.

20.

Sim1 is a novel regulator in the differentiation of mouse dorsal raphe serotonergic neurons.

Osterberg N, Wiehle M, Oehlke O, Heidrich S, Xu C, Fan CM, Krieglstein K, Roussa E.

PLoS One. 2011 Apr 26;6(4):e19239. doi: 10.1371/journal.pone.0019239.

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