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Items: 1 to 20 of 56

1.

Trans-acting GC-rich non-coding RNA at var expression site modulates gene counting in malaria parasite.

Guizetti J, Barcons-Simon A, Scherf A.

Nucleic Acids Res. 2016 Nov 16;44(20):9710-9718. Epub 2016 Jul 27.

2.

Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing.

Vembar SS, Seetin M, Lambert C, Nattestad M, Schatz MC, Baybayan P, Scherf A, Smith ML.

DNA Res. 2016 Aug;23(4):339-51. doi: 10.1093/dnares/dsw022. Epub 2016 Jun 26.

3.

Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems-wide studies pave the way.

Vembar SS, Droll D, Scherf A.

Wiley Interdiscip Rev RNA. 2016 Nov;7(6):772-792. doi: 10.1002/wrna.1365. Epub 2016 May 26. Review.

4.

Orientation relationship of eutectoid FeAl and FeAl2.

Scherf A, Kauffmann A, Kauffmann-Weiss S, Scherer T, Li X, Stein F, Heilmaier M.

J Appl Crystallogr. 2016 Feb 24;49(Pt 2):442-449. eCollection 2016 Apr 1.

5.

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites.

Chen PB, Ding S, Zanghì G, Soulard V, DiMaggio PA, Fuchter MJ, Mecheri S, Mazier D, Scherf A, Malmquist NA.

Sci Rep. 2016 Feb 23;6:21802. doi: 10.1038/srep21802.

6.

The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages.

Vembar SS, Macpherson CR, Sismeiro O, Coppée JY, Scherf A.

Genome Biol. 2015 Sep 28;16:212. doi: 10.1186/s13059-015-0771-5.

7.

Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).

Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL.

J Med Chem. 2015 Jul 23;58(14):5579-98. doi: 10.1021/acs.jmedchem.5b00606. Epub 2015 Jun 30.

8.

RNase II: A new player enters the game.

Zhang Q, Scherf A.

RNA Biol. 2015;12(6):586-9. doi: 10.1080/15476286.2015.1038013.

9.

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.

Malmquist NA, Sundriyal S, Caron J, Chen P, Witkowski B, Menard D, Suwanarusk R, Renia L, Nosten F, Jiménez-Díaz MB, Angulo-Barturen I, Santos Martínez M, Ferrer S, Sanz LM, Gamo FJ, Wittlin S, Duffy S, Avery VM, Ruecker A, Delves MJ, Sinden RE, Fuchter MJ, Scherf A.

Antimicrob Agents Chemother. 2015 Feb;59(2):950-9. doi: 10.1128/AAC.04419-14. Epub 2014 Nov 24.

10.

P. berghei telomerase subunit TERT is essential for parasite survival.

Religa AA, Ramesar J, Janse CJ, Scherf A, Waters AP.

PLoS One. 2014 Oct 2;9(9):e108930. doi: 10.1371/journal.pone.0108930. eCollection 2014.

11.

Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds.

Sundriyal S, Malmquist NA, Caron J, Blundell S, Liu F, Chen X, Srimongkolpithak N, Jin J, Charman SA, Scherf A, Fuchter MJ.

ChemMedChem. 2014 Oct;9(10):2360-2373. doi: 10.1002/cmdc.201402098. Epub 2014 Jul 9.

12.

Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression.

Vembar SS, Scherf A, Siegel TN.

Curr Opin Microbiol. 2014 Aug;20:153-61. doi: 10.1016/j.mib.2014.06.013. Epub 2014 Jul 12. Review.

13.

Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum.

Siegel TN, Hon CC, Zhang Q, Lopez-Rubio JJ, Scheidig-Benatar C, Martins RM, Sismeiro O, Coppée JY, Scherf A.

BMC Genomics. 2014 Feb 22;15:150. doi: 10.1186/1471-2164-15-150.

14.

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum.

Jiang L, Mu J, Zhang Q, Ni T, Srinivasan P, Rayavara K, Yang W, Turner L, Lavstsen T, Theander TG, Peng W, Wei G, Jing Q, Wakabayashi Y, Bansal A, Luo Y, Ribeiro JM, Scherf A, Aravind L, Zhu J, Zhao K, Miller LH.

Nature. 2013 Jul 11;499(7457):223-7. doi: 10.1038/nature12361. Epub 2013 Jul 3.

15.

Nuclear pores and perinuclear expression sites of var and ribosomal DNA genes correspond to physically distinct regions in Plasmodium falciparum.

Guizetti J, Martins RM, Guadagnini S, Claes A, Scherf A.

Eukaryot Cell. 2013 May;12(5):697-702. doi: 10.1128/EC.00023-13. Epub 2013 Mar 8.

16.

Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum.

Mancio-Silva L, Lopez-Rubio JJ, Claes A, Scherf A.

Nat Commun. 2013;4:1530. doi: 10.1038/ncomms2539.

17.

Silence, activate, poise and switch! Mechanisms of antigenic variation in Plasmodium falciparum.

Guizetti J, Scherf A.

Cell Microbiol. 2013 May;15(5):718-26. doi: 10.1111/cmi.12115. Epub 2013 Feb 21. Review.

18.

Comprehensive histone phosphorylation analysis and identification of Pf14-3-3 protein as a histone H3 phosphorylation reader in malaria parasites.

Dastidar EG, Dzeyk K, Krijgsveld J, Malmquist NA, Doerig C, Scherf A, Lopez-Rubio JJ.

PLoS One. 2013;8(1):e53179. doi: 10.1371/journal.pone.0053179. Epub 2013 Jan 7.

19.

Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria.

Fried M, Avril M, Chaturvedi R, Fernandez P, Lograsso J, Narum D, Nielsen MA, Oleinikov AV, Resende M, Salanti A, Saveria T, Williamson K, Dicko A, Scherf A, Smith JD, Theander TG, Duffy PE.

Infect Immun. 2013 Feb;81(2):487-95. doi: 10.1128/IAI.01106-12. Epub 2012 Dec 3.

20.

Initial characterization of the Pf-Int recombinase from the malaria parasite Plasmodium falciparum.

Ghorbal M, Scheidig-Benatar C, Bouizem S, Thomas C, Paisley G, Faltermeier C, Liu M, Scherf A, Lopez-Rubio JJ, Gopaul DN.

PLoS One. 2012;7(10):e46507. doi: 10.1371/journal.pone.0046507. Epub 2012 Oct 8.

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