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Items: 1 to 20 of 21

1.

A Critical Role for HlgA in Staphylococcus aureus Pathogenesis Revealed by A Switch in the SaeRS Two-Component Regulatory System.

Venkatasubramaniam A, Kanipakala T, Ganjbaksh N, Mehr R, Mukherjee I, Krishnan S, Bae T, Aman MJ, Adhikari RP.

Toxins (Basel). 2018 Sep 18;10(9). pii: E377. doi: 10.3390/toxins10090377.

2.

Protective efficacy of a novel alpha hemolysin subunit vaccine (AT62) against Staphylococcus aureus skin and soft tissue infections.

Adhikari RP, Thompson CD, Aman MJ, Lee JC.

Vaccine. 2016 Dec 7;34(50):6402-6407. doi: 10.1016/j.vaccine.2016.09.061. Epub 2016 Nov 12.

3.

Safety and Immunogenicity of a Parenterally Administered, Structure-Based Rationally Modified Recombinant Staphylococcal Enterotoxin B Protein Vaccine, STEBVax.

Chen WH, Pasetti MF, Adhikari RP, Baughman H, Douglas R, El-Khorazaty J, Greenberg N, Holtsberg FW, Liao GC, Reymann MK, Wang X, Warfield KL, Aman MJ.

Clin Vaccine Immunol. 2016 Dec 5;23(12):918-925. Print 2016 Dec.

4.

Development of a novel multiplex electrochemiluminescent-based immunoassay for quantification of human serum IgG against 10 Staphylococcus aureus toxins.

Adhikari RP, Haudenschild C, Sterba PM, Sahandi S, Enterlein S, Holtsberg FW, Aman MJ.

J Immunol Methods. 2016 Mar;430:33-42. doi: 10.1016/j.jim.2016.01.013. Epub 2016 Jan 27.

PMID:
26826278
5.

Correction: Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.

Adhikari RP, Kort T, Shulenin S, Kanipakala T, Ganjbaksh N, Roghmann MC, Holtsberg FW, Aman MJ.

PLoS One. 2015 Nov 16;10(11):e0143493. doi: 10.1371/journal.pone.0143493. eCollection 2015. No abstract available.

6.

Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.

Adhikari RP, Kort T, Shulenin S, Kanipakala T, Ganjbaksh N, Roghmann MC, Holtsberg FW, Aman MJ.

PLoS One. 2015 Sep 14;10(9):e0137874. doi: 10.1371/journal.pone.0137874. eCollection 2015. Erratum in: PLoS One. 2015;10(11):e0143493.

7.

Staphylococcal bicomponent pore-forming toxins: targets for prophylaxis and immunotherapy.

Aman MJ, Adhikari RP.

Toxins (Basel). 2014 Mar 4;6(3):950-72. doi: 10.3390/toxins6030950. Review.

8.

Structurally designed attenuated subunit vaccines for S. aureus LukS-PV and LukF-PV confer protection in a mouse bacteremia model.

Karauzum H, Adhikari RP, Sarwar J, Devi VS, Abaandou L, Haudenschild C, Mahmoudieh M, Boroun AR, Vu H, Nguyen T, Warfield KL, Shulenin S, Aman MJ.

PLoS One. 2013 Jun 7;8(6):e65384. doi: 10.1371/journal.pone.0065384. Print 2013.

9.

Lower antibody levels to Staphylococcus aureus exotoxins are associated with sepsis in hospitalized adults with invasive S. aureus infections.

Adhikari RP, Ajao AO, Aman MJ, Karauzum H, Sarwar J, Lydecker AD, Johnson JK, Nguyen C, Chen WH, Roghmann MC.

J Infect Dis. 2012 Sep 15;206(6):915-23. doi: 10.1093/infdis/jis462. Epub 2012 Jul 17.

PMID:
22807524
10.

Novel structurally designed vaccine for S. aureus α-hemolysin: protection against bacteremia and pneumonia.

Adhikari RP, Karauzum H, Sarwar J, Abaandou L, Mahmoudieh M, Boroun AR, Vu H, Nguyen T, Devi VS, Shulenin S, Warfield KL, Aman MJ.

PLoS One. 2012;7(6):e38567. doi: 10.1371/journal.pone.0038567. Epub 2012 Jun 6.

11.

Mutations in agr do not persist in natural populations of methicillin-resistant Staphylococcus aureus.

Shopsin B, Eaton C, Wasserman GA, Mathema B, Adhikari RP, Agolory S, Altman DR, Holzman RS, Kreiswirth BN, Novick RP.

J Infect Dis. 2010 Nov 15;202(10):1593-9. doi: 10.1086/656915. Epub 2010 Oct 13.

PMID:
20942648
12.

Prevalence of agr dysfunction among colonizing Staphylococcus aureus strains.

Shopsin B, Drlica-Wagner A, Mathema B, Adhikari RP, Kreiswirth BN, Novick RP.

J Infect Dis. 2008 Oct 15;198(8):1171-4. doi: 10.1086/592051.

PMID:
18752431
13.

Regulatory organization of the staphylococcal sae locus.

Adhikari RP, Novick RP.

Microbiology. 2008 Mar;154(Pt 3):949-59. doi: 10.1099/mic.0.2007/012245-0.

PMID:
18310041
14.

Sequence analysis reveals genetic exchanges and intraspecific spread of SaPI2, a pathogenicity island involved in menstrual toxic shock.

Subedi A, Ubeda C, Adhikari RP, Penadés JR, Novick RP.

Microbiology. 2007 Oct;153(Pt 10):3235-45.

PMID:
17906123
15.
16.

Fitness cost of staphylococcal cassette chromosome mec in methicillin-resistant Staphylococcus aureus by way of continuous culture.

Lee SM, Ender M, Adhikari R, Smith JM, Berger-Bächi B, Cook GM.

Antimicrob Agents Chemother. 2007 Apr;51(4):1497-9. Epub 2007 Feb 5.

17.

Inhibition of rot translation by RNAIII, a key feature of agr function.

Geisinger E, Adhikari RP, Jin R, Ross HF, Novick RP.

Mol Microbiol. 2006 Aug;61(4):1038-48.

18.
19.

Vancomycin-induced deletion of the methicillin resistance gene mecA in Staphylococcus aureus.

Adhikari RP, Scales GC, Kobayashi K, Smith JM, Berger-Bächi B, Cook GM.

J Antimicrob Chemother. 2004 Aug;54(2):360-3. Epub 2004 Jul 8.

20.

Fitness cost of SCCmec and methicillin resistance levels in Staphylococcus aureus.

Ender M, McCallum N, Adhikari R, Berger-Bächi B.

Antimicrob Agents Chemother. 2004 Jun;48(6):2295-7.

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