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Items: 18


Sequential replication-coupled destruction at G1/S ensures genome stability.

Coleman KE, Grant GD, Haggerty RA, Brantley K, Shibata E, Workman BD, Dutta A, Varma D, Purvis JE, Cook JG.

Genes Dev. 2015 Aug 15;29(16):1734-46. doi: 10.1101/gad.263731.115.


Multi-scale imaging and informatics pipeline for in situ pluripotent stem cell analysis.

Gorman BR, Lu J, Baccei A, Lowry NC, Purvis JE, Mangoubi RS, Lerou PH.

PLoS One. 2014 Dec 31;9(12):e116037. doi: 10.1371/journal.pone.0116037.


Computational analysis of signaling patterns in single cells.

Davis DM, Purvis JE.

Semin Cell Dev Biol. 2015 Jan;37:35-43. doi: 10.1016/j.semcdb.2014.09.015. Review.


Systems biology of platelet-vessel wall interactions.

Diamond SL, Purvis J, Chatterjee M, Flamm MH.

Front Physiol. 2013 Aug 26;4:229. doi: 10.3389/fphys.2013.00229.


Encoding and decoding cellular information through signaling dynamics.

Purvis JE, Lahav G.

Cell. 2013 Feb 28;152(5):945-56. doi: 10.1016/j.cell.2013.02.005. Review.


Decoding the insulin signal.

Purvis JE, Lahav G.

Mol Cell. 2012 Jun 29;46(6):715-6. doi: 10.1016/j.molcel.2012.06.005.


p53 dynamics control cell fate.

Purvis JE, Karhohs KW, Mock C, Batchelor E, Loewer A, Lahav G.

Science. 2012 Jun 15;336(6087):1440-4. doi: 10.1126/science.1218351.


Cancer Cell: Linking Oncogenic Signaling to Molecular Structure.

Purvis JE, Shih AJ, Liu Y, Radhakrishnan R.

Chapman Hall CRC Math Comput Biol Ser. 2011;2011:31-44.


Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli.

Chatterjee MS, Purvis JE, Brass LF, Diamond SL.

Nat Biotechnol. 2010 Jul;28(7):727-32. doi: 10.1038/nbt.1642.


A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells.

Shah PP, Wang T, Kaletsky RL, Myers MC, Purvis JE, Jing H, Huryn DM, Greenbaum DC, Smith AB 3rd, Bates P, Diamond SL.

Mol Pharmacol. 2010 Aug;78(2):319-24. doi: 10.1124/mol.110.064261.


Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing.

Shih AJ, Purvis J, Radhakrishnan R.

Mol Biosyst. 2008 Dec;4(12):1151-9. doi: 10.1039/b803806f.


Steady-state kinetic modeling constrains cellular resting states and dynamic behavior.

Purvis JE, Radhakrishnan R, Diamond SL.

PLoS Comput Biol. 2009 Mar;5(3):e1000298. doi: 10.1371/journal.pcbi.1000298.


Molecular docking of cathepsin L inhibitors in the binding site of papain.

Beavers MP, Myers MC, Shah PP, Purvis JE, Diamond SL, Cooperman BS, Huryn DM, Smith AB 3rd.

J Chem Inf Model. 2008 Jul;48(7):1464-72. doi: 10.1021/ci800085c. Erratum in: J Chem Inf Model. 2010 Dec 27;50(12):2274.


A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation.

Purvis JE, Chatterjee MS, Brass LF, Diamond SL.

Blood. 2008 Nov 15;112(10):4069-79. doi: 10.1182/blood-2008-05-157883.


Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L.

Shah PP, Myers MC, Beavers MP, Purvis JE, Jing H, Grieser HJ, Sharlow ER, Napper AD, Huryn DM, Cooperman BS, Smith AB 3rd, Diamond SL.

Mol Pharmacol. 2008 Jul;74(1):34-41. doi: 10.1124/mol.108.046219.


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