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Items: 20

1.

Intranuclear delivery of synthetic nuclear factor-kappa B p65 reduces inflammasomes after surgery.

Cheon SY, Kim JM, Kim EJ, Kim SY, Kam EH, Ho CC, Lee SK, Koo BN.

Biochem Pharmacol. 2018 Aug 7. pii: S0006-2952(18)30326-5. doi: 10.1016/j.bcp.2018.08.006. [Epub ahead of print]

PMID:
30096289
2.

Ginsenoside Rg1 protects against neuronal degeneration induced by chronic dexamethasone treatment by inhibiting NLRP-1 inflammasomes in mice.

Zhang Y, Hu W, Zhang B, Yin Y, Zhang J, Huang D, Huang R, Li W, Li W.

Int J Mol Med. 2017 Oct;40(4):1134-1142. doi: 10.3892/ijmm.2017.3092. Epub 2017 Aug 9.

3.

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation.

García-Laínez G, Sancho M, García-Bayarri V, Orzáez M.

Apoptosis. 2017 Oct;22(10):1310-1318. doi: 10.1007/s10495-017-1405-z.

4.

Chronic glucocorticoid exposure activates BK-NLRP1 signal involving in hippocampal neuron damage.

Zhang B, Zhang Y, Wu W, Xu T, Yin Y, Zhang J, Huang D, Li W.

J Neuroinflammation. 2017 Jul 21;14(1):139. doi: 10.1186/s12974-017-0911-9.

5.

Chronic dexamethasone treatment results in hippocampal neurons injury due to activate NLRP1 inflammasome in vitro.

Zhang B, Zhang Y, Xu T, Yin Y, Huang R, Wang Y, Zhang J, Huang D, Li W.

Int Immunopharmacol. 2017 Aug;49:222-230. doi: 10.1016/j.intimp.2017.05.039. Epub 2017 Jun 9.

PMID:
28605710
6.

Novel therapeutic target against Alzheimer.

LeBlanc AC.

Oncotarget. 2017 Jul 25;8(30):48529-48530. doi: 10.18632/oncotarget.18210. No abstract available.

7.

Inflammasomes as therapeutic targets for Alzheimer's disease.

White CS, Lawrence CB, Brough D, Rivers-Auty J.

Brain Pathol. 2017 Mar;27(2):223-234. doi: 10.1111/bpa.12478. Review.

PMID:
28009077
8.

Inflammasomes link vascular disease with neuroinflammation and brain disorders.

Lénárt N, Brough D, Dénes Á.

J Cereb Blood Flow Metab. 2016 Oct;36(10):1668-1685. Epub 2016 Aug 2. Review.

9.

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

Saresella M, La Rosa F, Piancone F, Zoppis M, Marventano I, Calabrese E, Rainone V, Nemni R, Mancuso R, Clerici M.

Mol Neurodegener. 2016 Mar 3;11:23. doi: 10.1186/s13024-016-0088-1.

10.

Chronic glucocorticoids exposure enhances neurodegeneration in the frontal cortex and hippocampus via NLRP-1 inflammasome activation in male mice.

Hu W, Zhang Y, Wu W, Yin Y, Huang D, Wang Y, Li W, Li W.

Brain Behav Immun. 2016 Feb;52:58-70. doi: 10.1016/j.bbi.2015.09.019. Epub 2015 Oct 3.

PMID:
26434621
11.

The pathogenic role of the inflammasome in neurodegenerative diseases.

Freeman LC, Ting JP.

J Neurochem. 2016 Jan;136 Suppl 1:29-38. doi: 10.1111/jnc.13217. Epub 2015 Sep 2. Review.

12.

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.

Kaushal V, Dye R, Pakavathkumar P, Foveau B, Flores J, Hyman B, Ghetti B, Koller BH, LeBlanc AC.

Cell Death Differ. 2015 Oct;22(10):1676-86. doi: 10.1038/cdd.2015.16. Epub 2015 Mar 6.

13.

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA.

Nat Med. 2015 Mar;21(3):248-55. doi: 10.1038/nm.3806. Epub 2015 Feb 16.

14.

Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer's disease.

Tan MS, Tan L, Jiang T, Zhu XC, Wang HF, Jia CD, Yu JT.

Cell Death Dis. 2014 Aug 21;5:e1382. doi: 10.1038/cddis.2014.348.

15.

Inflammasomes: molecular regulation and implications for metabolic and cognitive diseases.

Choi AJ, Ryter SW.

Mol Cells. 2014 Jun;37(6):441-8. doi: 10.14348/molcells.2014.0104. Epub 2014 May 19. Review.

16.

Reconstituting the NLRP1 inflammasome in vitro.

Faustin B, Reed JC.

Methods Mol Biol. 2013;1040:137-52. doi: 10.1007/978-1-62703-523-1_11.

PMID:
23852602
17.

Specific inflammasomes in complex diseases.

Masters SL.

Clin Immunol. 2013 Jun;147(3):223-8. doi: 10.1016/j.clim.2012.12.006. Epub 2012 Dec 21. Review.

PMID:
23294928
18.

NALP1/NLRP1 genetic variants are associated with Alzheimer disease.

Pontillo A, Catamo E, Arosio B, Mari D, Crovella S.

Alzheimer Dis Assoc Disord. 2012 Jul-Sep;26(3):277-81. doi: 10.1097/WAD.0b013e318231a8ac.

PMID:
21946017
19.
20.

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

Salminen A, Ojala J, Suuronen T, Kaarniranta K, Kauppinen A.

J Cell Mol Med. 2008 Dec;12(6A):2255-62. doi: 10.1111/j.1582-4934.2008.00496.x. Epub 2008 Sep 13. Review.

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