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Items: 1 to 20 of 49

1.

Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation.

De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM.

Nature. 2019 Aug;572(7767):E5. doi: 10.1038/s41586-019-1350-9.

PMID:
31296937
2.

Bayesian Estimation of Three-Dimensional Chromosomal Structure from Single-Cell Hi-C Data.

Rosenthal M, Bryner D, Huffer F, Evans S, Srivastava A, Neretti N.

J Comput Biol. 2019 Nov;26(11):1191-1202. doi: 10.1089/cmb.2019.0100. Epub 2019 Jun 18.

3.

Single cell RNA-seq in the sea urchin embryo show marked cell-type specificity in the Delta/Notch pathway.

Foster S, Teo YV, Neretti N, Oulhen N, Wessel GM.

Mol Reprod Dev. 2019 Aug;86(8):931-934. doi: 10.1002/mrd.23181. Epub 2019 Jun 14.

PMID:
31199038
4.

Notch Signaling Mediates Secondary Senescence.

Teo YV, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, Kiourtis C, Müller M, Green AR, Adams PD, Acosta JC, Bird TG, Kirschner K, Neretti N, Chandra T.

Cell Rep. 2019 Apr 23;27(4):997-1007.e5. doi: 10.1016/j.celrep.2019.03.104.

5.

LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.

Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, Antoch MP, Gudkov AV, Sedivy JM, Seluanov A, Gorbunova V.

Cell Metab. 2019 Apr 2;29(4):871-885.e5. doi: 10.1016/j.cmet.2019.02.014. Epub 2019 Mar 7.

PMID:
30853213
6.

L1 drives IFN in senescent cells and promotes age-associated inflammation.

De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM.

Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9. Epub 2019 Feb 6. Erratum in: Nature. 2019 Aug;572(7767):E5.

7.

Cell-free DNA as a biomarker of aging.

Teo YV, Capri M, Morsiani C, Pizza G, Faria AMC, Franceschi C, Neretti N.

Aging Cell. 2019 Feb;18(1):e12890. doi: 10.1111/acel.12890. Epub 2018 Dec 20.

8.

Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells.

Gruppuso PA, Boylan JM, Zabala V, Neretti N, Abshiru NA, Sikora JW, Doud EH, Camarillo JM, Thomas PM, Kelleher NL, Sanders JA.

PLoS One. 2018 Sep 7;13(9):e0203351. doi: 10.1371/journal.pone.0203351. eCollection 2018.

9.

The three-dimensional organization of the genome in cellular senescence and age-associated diseases.

Evans SA, Horrell J, Neretti N.

Semin Cell Dev Biol. 2019 Jun;90:154-160. doi: 10.1016/j.semcdb.2018.07.022. Epub 2018 Jul 27. Review.

10.

Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways.

Ito T, Teo YV, Evans SA, Neretti N, Sedivy JM.

Cell Rep. 2018 Mar 27;22(13):3480-3492. doi: 10.1016/j.celrep.2018.03.002.

11.

GINOM: A statistical framework for assessing interval overlap of multiple genomic features.

Bryner D, Criscione S, Leith A, Huynh Q, Huffer F, Neretti N.

PLoS Comput Biol. 2017 Jun 15;13(6):e1005586. doi: 10.1371/journal.pcbi.1005586. eCollection 2017 Jun.

12.

The Chromatin Landscape of Cellular Senescence.

Criscione SW, Teo YV, Neretti N.

Trends Genet. 2016 Nov;32(11):751-761. doi: 10.1016/j.tig.2016.09.005. Epub 2016 Sep 28. Review.

13.

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.

Wood JG, Jones BC, Jiang N, Chang C, Hosier S, Wickremesinghe P, Garcia M, Hartnett DA, Burhenn L, Neretti N, Helfand SL.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11277-11282. Epub 2016 Sep 12.

14.

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.

Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT, Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL, Nixon C, Clark W, Riethman H, Wu H, Schotta G, Garcia BA, Neretti N, Baird DM, Berger SL, Adams PD.

Genome Biol. 2016 Jul 25;17(1):158. doi: 10.1186/s13059-016-1017-x.

15.

Genome-wide characterization of human L1 antisense promoter-driven transcripts.

Criscione SW, Theodosakis N, Micevic G, Cornish TC, Burns KH, Neretti N, Rodić N.

BMC Genomics. 2016 Jun 14;17:463. doi: 10.1186/s12864-016-2800-5.

16.

Reorganization of chromosome architecture in replicative cellular senescence.

Criscione SW, De Cecco M, Siranosian B, Zhang Y, Kreiling JA, Sedivy JM, Neretti N.

Sci Adv. 2016 Feb 5;2(2):e1500882. doi: 10.1126/sciadv.1500882. eCollection 2016 Feb.

17.

Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR).

Boylan JM, Sanders JA, Neretti N, Gruppuso PA.

Am J Physiol Regul Integr Comp Physiol. 2015 Jul 1;309(1):R22-35. doi: 10.1152/ajpregu.00114.2015. Epub 2015 Apr 29.

18.

Enhancement of radiation effect on cancer cells by gold-pHLIP.

Antosh MP, Wijesinghe DD, Shrestha S, Lanou R, Huang YH, Hasselbacher T, Fox D, Neretti N, Sun S, Katenka N, Cooper LN, Andreev OA, Reshetnyak YK.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5372-6. doi: 10.1073/pnas.1501628112. Epub 2015 Apr 13.

19.

Reduced expression of MYC increases longevity and enhances healthspan.

Hofmann JW, Zhao X, De Cecco M, Peterson AL, Pagliaroli L, Manivannan J, Hubbard GB, Ikeno Y, Zhang Y, Feng B, Li X, Serre T, Qi W, Van Remmen H, Miller RA, Bath KG, de Cabo R, Xu H, Neretti N, Sedivy JM.

Cell. 2015 Jan 29;160(3):477-88. doi: 10.1016/j.cell.2014.12.016. Epub 2015 Jan 22.

20.

Drosophila melanogaster show a threshold effect in response to radiation.

Antosh M, Fox D, Hasselbacher T, Lanou R, Neretti N, Cooper LN.

Dose Response. 2014 May 5;12(4):551-81. doi: 10.2203/dose-response.13-047.Antosh. eCollection 2014 Dec.

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