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Items: 20


Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells.

van Buggenum JAG, Gerlach JP, Tanis SEJ, Hogeweg M, Jansen PWTC, Middelwijk J, van der Steen R, Vermeulen M, Stunnenberg HG, Albers CA, Mulder KW.

Nat Commun. 2018 Jun 19;9(1):2384. doi: 10.1038/s41467-018-04761-0.


TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers.

Serandour AA, Mohammed H, Miremadi A, Mulder KW, Carroll JS.

Oncogene. 2018 Jun 12. doi: 10.1038/s41388-018-0312-2. [Epub ahead of print]


Adaptation trajectories during adhesion and spreading affect future cell states.

Bruekers SMC, Bao M, Hendriks JMA, Mulder KW, Huck WTS.

Sci Rep. 2017 Sep 26;7(1):12308. doi: 10.1038/s41598-017-12467-4.


Reactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity.

van Eijl RAPM, van den Brand T, Nguyen LN, Mulder KW.

Sci Rep. 2017 Aug 4;7(1):7278. doi: 10.1038/s41598-017-07539-4.


Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties.

Donati G, Rognoni E, Hiratsuka T, Liakath-Ali K, Hoste E, Kar G, Kayikci M, Russell R, Kretzschmar K, Mulder KW, Teichmann SA, Watt FM.

Nat Cell Biol. 2017 Jun;19(6):603-613. doi: 10.1038/ncb3532. Epub 2017 May 15.


A covalent and cleavable antibody-DNA conjugation strategy for sensitive protein detection via immuno-PCR.

van Buggenum JA, Gerlach JP, Eising S, Schoonen L, van Eijl RA, Tanis SE, Hogeweg M, Hubner NC, van Hest JC, Bonger KM, Mulder KW.

Sci Rep. 2016 Mar 7;6:22675. doi: 10.1038/srep22675.


Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism.

Stout GJ, Stigter EC, Essers PB, Mulder KW, Kolkman A, Snijders DS, van den Broek NJ, Betist MC, Korswagen HC, Macinnes AW, Brenkman AB.

Mol Syst Biol. 2013 Jul 2;9:679. doi: 10.1038/msb.2013.35.


Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations.

Wang X, Castro MA, Mulder KW, Markowetz F.

PLoS Comput Biol. 2012;8(6):e1002566. doi: 10.1371/journal.pcbi.1002566. Epub 2012 Jun 28.


Diverse epigenetic strategies interact to control epidermal differentiation.

Mulder KW, Wang X, Escriu C, Ito Y, Schwarz RF, Gillis J, Sirokmány G, Donati G, Uribe-Lewis S, Pavlidis P, Murrell A, Markowetz F, Watt FM.

Nat Cell Biol. 2012 Jun 24;14(7):753-63. doi: 10.1038/ncb2520.


FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.

Goldie SJ, Mulder KW, Tan DW, Lyons SK, Sims AH, Watt FM.

Cancer Res. 2012 Jul 1;72(13):3424-36. doi: 10.1158/0008-5472.CAN-12-0423. Epub 2012 May 7.


Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells.

Markowetz F, Mulder KW, Airoldi EM, Lemischka IR, Troyanskaya OG.

PLoS Comput Biol. 2010 Dec 16;6(12):e1001034. doi: 10.1371/journal.pcbi.1001034.


Phosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiae.

Lau NC, Mulder KW, Brenkman AB, Mohammed S, van den Broek NJ, Heck AJ, Timmers HT.

PLoS One. 2010 Apr 8;5(4):e9864. doi: 10.1371/journal.pone.0009864.


Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis.

Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM.

Development. 2009 Aug;136(16):2815-23. doi: 10.1242/dev.038620. Epub 2009 Jul 15.


Human Ccr4-Not complexes contain variable deadenylase subunits.

Lau NC, Kolkman A, van Schaik FM, Mulder KW, Pijnappel WW, Heck AJ, Timmers HT.

Biochem J. 2009 Aug 27;422(3):443-53. doi: 10.1042/BJ20090500.


Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.

Vermeulen M, Mulder KW, Denissov S, Pijnappel WW, van Schaik FM, Varier RA, Baltissen MP, Stunnenberg HG, Mann M, Timmers HT.

Cell. 2007 Oct 5;131(1):58-69. Epub 2007 Sep 20.


Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae.

Mulder KW, Inagaki A, Cameroni E, Mousson F, Winkler GS, De Virgilio C, Collart MA, Timmers HT.

Genetics. 2007 May;176(1):181-92.


Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex.

Mulder KW, Brenkman AB, Inagaki A, van den Broek NJ, Timmers HT.

Nucleic Acids Res. 2007;35(7):2428-39. Epub 2007 Mar 28.


Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription.

Winkler GS, Mulder KW, Bardwell VJ, Kalkhoven E, Timmers HT.

EMBO J. 2006 Jul 12;25(13):3089-99. Epub 2006 Jun 15.


Menin links estrogen receptor activation to histone H3K4 trimethylation.

Dreijerink KM, Mulder KW, Winkler GS, Höppener JW, Lips CJ, Timmers HT.

Cancer Res. 2006 May 1;66(9):4929-35.


DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.

Mulder KW, Winkler GS, Timmers HT.

Nucleic Acids Res. 2005 Nov 7;33(19):6384-92. Print 2005.

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