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Retraction Notice to: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation.

Yi P, Park JS, Melton DA.

Cell. 2017 Jan 12;168(1-2):326. doi: 10.1016/j.cell.2016.12.017. Epub 2016 Dec 28. No abstract available.


A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.

Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I.

Cell Syst. 2016 Oct 26;3(4):346-360.e4. doi: 10.1016/j.cels.2016.08.011. Epub 2016 Sep 22.


Corrigendum: Generation of stem cell-derived β-cells from patients with type 1 diabetes.

Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA.

Nat Commun. 2016 Aug 4;7:12379. doi: 10.1038/ncomms12379. No abstract available.


Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy.

Cox AR, Barrandon O, Cai EP, Rios JS, Chavez J, Bonnyman CW, Lam CJ, Yi P, Melton DA, Kushner JA.

PLoS One. 2016 Jul 13;11(7):e0159276. doi: 10.1371/journal.pone.0159276. eCollection 2016.


Generation of stem cell-derived β-cells from patients with type 1 diabetes.

Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA.

Nat Commun. 2016 May 10;7:11463. doi: 10.1038/ncomms11463.


Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation.

Ariyachet C, Tovaglieri A, Xiang G, Lu J, Shah MS, Richmond CA, Verbeke C, Melton DA, Stanger BZ, Mooney D, Shivdasani RA, Mahony S, Xia Q, Breault DT, Zhou Q.

Cell Stem Cell. 2016 Mar 3;18(3):410-21. doi: 10.1016/j.stem.2016.01.003. Epub 2016 Feb 18.


Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice.

Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG.

Nat Med. 2016 Mar;22(3):306-11. doi: 10.1038/nm.4030. Epub 2016 Jan 25. Erratum in: Nat Med. 2016 Apr;22(4):446.


Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.

Ben-Zvi D, Barrandon O, Hadley S, Blum B, Peterson QP, Melton DA.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15498-503. doi: 10.1073/pnas.1513872112. Epub 2015 Nov 30.


A Src inhibitor regulates the cell cycle of human pluripotent stem cells and improves directed differentiation.

Chetty S, Engquist EN, Mehanna E, Lui KO, Tsankov AM, Melton DA.

J Cell Biol. 2015 Sep 28;210(7):1257-68. doi: 10.1083/jcb.201502035.


Testing pancreatic islet function at the single cell level by calcium influx with associated marker expression.

Kenty JH, Melton DA.

PLoS One. 2015 Apr 8;10(4):e0122044. doi: 10.1371/journal.pone.0122044. eCollection 2015.


Generation of functional human pancreatic β cells in vitro.

Pagliuca FW, Millman JR, Gürtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA.

Cell. 2014 Oct 9;159(2):428-39. doi: 10.1016/j.cell.2014.09.040.


Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.

Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA.

Elife. 2014 Sep 16;3:e02809. doi: 10.7554/eLife.02809.


In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes.

Li W, Nakanishi M, Zumsteg A, Shear M, Wright C, Melton DA, Zhou Q.

Elife. 2014 Jan 1;3:e01846. doi: 10.7554/eLife.01846.


MARIS: method for analyzing RNA following intracellular sorting.

Hrvatin S, Deng F, O'Donnell CW, Gifford DK, Melton DA.

PLoS One. 2014 Mar 3;9(3):e89459. doi: 10.1371/journal.pone.0089459. eCollection 2014.


Differentiated human stem cells resemble fetal, not adult, β cells.

Hrvatin S, O'Donnell CW, Deng F, Millman JR, Pagliuca FW, DiIorio P, Rezania A, Gifford DK, Melton DA.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3038-43. doi: 10.1073/pnas.1400709111. Epub 2014 Feb 10.


Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells.

Tajonar A, Maehr R, Hu G, Sneddon JB, Rivera-Feliciano J, Cohen DE, Elledge SJ, Melton DA.

Stem Cells. 2013 Dec;31(12):2833-41. doi: 10.1002/stem.1445.


How to make a functional β-cell.

Pagliuca FW, Melton DA.

Development. 2013 Jun;140(12):2472-83. doi: 10.1242/dev.093187. Review.


Betatrophin: a hormone that controls pancreatic β cell proliferation.

Yi P, Park JS, Melton DA.

Cell. 2013 May 9;153(4):747-58. doi: 10.1016/j.cell.2013.04.008. Epub 2013 Apr 25. Retraction in: Cell. 2017 Jan 12;168(1-2):326.


A simple tool to improve pluripotent stem cell differentiation.

Chetty S, Pagliuca FW, Honore C, Kweudjeu A, Rezania A, Melton DA.

Nat Methods. 2013 Jun;10(6):553-6. doi: 10.1038/nmeth.2442. Epub 2013 Apr 14.


Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.

Chen AE, Borowiak M, Sherwood RI, Kweudjeu A, Melton DA.

Development. 2013 Feb 1;140(3):675-86. doi: 10.1242/dev.085431.

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