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Items: 1 to 20 of 24


Determining the Potential of Mean Force for Amyloid-β Dimerization: Combining Self-Consistent Field Theory with Molecular Dynamics Simulation.

van der Munnik NP, Sajib MSJ, Moss MA, Wei T, Uline MJ.

J Chem Theory Comput. 2018 May 8;14(5):2696-2704. doi: 10.1021/acs.jctc.7b01057. Epub 2018 Apr 10.


Influence of gold nanoparticle surface chemistry and diameter upon Alzheimer's disease amyloid-β protein aggregation.

Moore KA, Pate KM, Soto-Ortega DD, Lohse S, van der Munnik N, Lim M, Jackson KS, Lyles VD, Jones L, Glassgow N, Napumecheno VM, Mobley S, Uline MJ, Mahtab R, Murphy CJ, Moss MA.

J Biol Eng. 2017 Feb 6;11:5. doi: 10.1186/s13036-017-0047-6. eCollection 2017.


Anthoxanthin Polyphenols Attenuate Aβ Oligomer-induced Neuronal Responses Associated with Alzheimer's Disease.

Pate KM, Rogers M, Reed JW, van der Munnik N, Vance SZ, Moss MA.

CNS Neurosci Ther. 2017 Feb;23(2):135-144. doi: 10.1111/cns.12659. Epub 2016 Nov 18.


Modulating amyloid-β aggregation: The effects of peptoid side chain placement and chirality.

Turner JP, Chastain SE, Park D, Moss MA, Servoss SL.

Bioorg Med Chem. 2017 Jan 1;25(1):20-26. doi: 10.1016/j.bmc.2016.10.007. Epub 2016 Oct 10.


Conformational Dynamics of Specific Aβ Oligomers Govern Their Ability To Replicate and Induce Neuronal Apoptosis.

Dean DN, Pate KM, Moss MA, Rangachari V.

Biochemistry. 2016 Apr 19;55(15):2238-50. doi: 10.1021/acs.biochem.6b00161. Epub 2016 Apr 7.


Molecular Signaling Mechanisms of Natural and Synthetic Retinoids for Inhibition of Pathogenesis in Alzheimer's Disease.

Chakrabarti M, McDonald AJ, Will Reed J, Moss MA, Das BC, Ray SK.

J Alzheimers Dis. 2016;50(2):335-52. doi: 10.3233/JAD-150450. Review.


Self-propagative replication of Aβ oligomers suggests potential transmissibility in Alzheimer disease.

Kumar A, Pate KM, Moss MA, Dean DN, Rangachari V.

PLoS One. 2014 Nov 3;9(11):e111492. doi: 10.1371/journal.pone.0111492. eCollection 2014.


Capillary electrophoresis for the analysis of the effect of sample preparation on early stages of Aβ1-40 aggregation.

Pryor NE, Moss MA, Hestekin CN.

Electrophoresis. 2014 Jul;35(12-13):1814-20. doi: 10.1002/elps.201400012. Epub 2014 Jun 5.


Rationally designed peptoids modulate aggregation of amyloid-beta 40.

Turner JP, Lutz-Rechtin T, Moore KA, Rogers L, Bhave O, Moss MA, Servoss SL.

ACS Chem Neurosci. 2014 Jul 16;5(7):552-8. doi: 10.1021/cn400221u. Epub 2014 Apr 16.


Unraveling the early events of amyloid-β protein (Aβ) aggregation: techniques for the determination of Aβ aggregate size.

Pryor NE, Moss MA, Hestekin CN.

Int J Mol Sci. 2012;13(3):3038-72. doi: 10.3390/ijms13033038. Epub 2012 Mar 7. Review.


Monitoring insulin aggregation via capillary electrophoresis.

Pryor E, Kotarek JA, Moss MA, Hestekin CN.

Int J Mol Sci. 2011;12(12):9369-88. doi: 10.3390/ijms12129369. Epub 2011 Dec 14.


Inhibition of amyloid-β aggregation by coumarin analogs can be manipulated by functionalization of the aromatic center.

Soto-Ortega DD, Murphy BP, Gonzalez-Velasquez FJ, Wilson KA, Xie F, Wang Q, Moss MA.

Bioorg Med Chem. 2011 Apr 15;19(8):2596-602. doi: 10.1016/j.bmc.2011.03.010. Epub 2011 Mar 12.


Activation of brain endothelium by soluble aggregates of the amyloid-β protein involves nuclear factor-κB.

Gonzalez-Velasquez F, Reed JW, Fuseler JW, Matherly EE, Kotarek JA, Soto-Ortega DD, Moss MA.

Curr Alzheimer Res. 2011 Feb;8(1):81-94.


Comparative study of inhibition at multiple stages of amyloid-beta self-assembly provides mechanistic insight.

Davis TJ, Soto-Ortega DD, Kotarek JA, Gonzalez-Velasquez FJ, Sivakumar K, Wu L, Wang Q, Moss MA.

Mol Pharmacol. 2009 Aug;76(2):405-13. doi: 10.1124/mol.109.055301. Epub 2009 May 29.


Soluble aggregates of the amyloid-beta peptide are trapped by serum albumin to enhance amyloid-beta activation of endothelial cells.

Reyes Barcelo AA, Gonzalez-Velasquez FJ, Moss MA.

J Biol Eng. 2009 Apr 27;3:5. doi: 10.1186/1754-1611-3-5.


Soluble aggregates of the amyloid-beta protein selectively stimulate permeability in human brain microvascular endothelial monolayers.

Gonzalez-Velasquez FJ, Kotarek JA, Moss MA.

J Neurochem. 2008 Oct;107(2):466-77. doi: 10.1111/j.1471-4159.2008.05618.x. Epub 2008 Sep 16.


Quartz crystal microbalance analysis of growth kinetics for aggregation intermediates of the amyloid-beta protein.

Kotarek JA, Johnson KC, Moss MA.

Anal Biochem. 2008 Jul 1;378(1):15-24. doi: 10.1016/j.ab.2008.03.022. Epub 2008 Mar 16.


Amyloid-beta aggregates formed at polar-nonpolar interfaces differ from amyloid-beta protofibrils produced in aqueous buffers.

Nichols MR, Moss MA, Reed DK, Hoh JH, Rosenberry TL.

Microsc Res Tech. 2005 Jul;67(3-4):164-74. Review.


Rapid assembly of amyloid-beta peptide at a liquid/liquid interface produces unstable beta-sheet fibers.

Nichols MR, Moss MA, Reed DK, Hoh JH, Rosenberry TL.

Biochemistry. 2005 Jan 11;44(1):165-73.


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