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Items: 17

1.

Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin.

Hagita S, Rogers MA, Pham T, Wen JR, Mlynarchik AK, Aikawa M, Aikawa E.

Sci Rep. 2018 Jun 13;8(1):9006. doi: 10.1038/s41598-018-27416-y.

2.

Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.

Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E.

Circulation. 2018 Mar 27. pii: CIRCULATIONAHA.117.032291. doi: 10.1161/CIRCULATIONAHA.117.032291. [Epub ahead of print]

PMID:
29588317
3.

Macrophage Heterogeneity Complicates Reversal of Calcification in Cardiovascular Tissues.

Rogers MA, Aikawa M, Aikawa E.

Circ Res. 2017 Jun 23;121(1):5-7. doi: 10.1161/CIRCRESAHA.117.311219. No abstract available.

4.

Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress.

Rogers MA, Maldonado N, Hutcheson JD, Goettsch C, Goto S, Yamada I, Faits T, Sesaki H, Aikawa M, Aikawa E.

Circ Res. 2017 Jul 21;121(3):220-233. doi: 10.1161/CIRCRESAHA.116.310293. Epub 2017 Jun 12.

5.

A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.

Goettsch C, Hutcheson JD, Hagita S, Rogers MA, Creager MD, Pham T, Choi J, Mlynarchik AK, Pieper B, Kjolby M, Aikawa M, Aikawa E.

Atherosclerosis. 2016 Aug;251:109-118. doi: 10.1016/j.atherosclerosis.2016.06.011. Epub 2016 Jun 9.

6.

Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.

Goettsch C, Hutcheson JD, Aikawa M, Iwata H, Pham T, Nykjaer A, Kjolby M, Rogers M, Michel T, Shibasaki M, Hagita S, Kramann R, Rader DJ, Libby P, Singh SA, Aikawa E.

J Clin Invest. 2016 Apr 1;126(4):1323-36. doi: 10.1172/JCI80851. Epub 2016 Mar 7.

7.

Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.

Huang LH, Melton EM, Li H, Sohn P, Rogers MA, Mulligan-Kehoe MJ, Fiering SN, Hickey WF, Chang CC, Chang TY.

J Biol Chem. 2016 Mar 18;291(12):6232-44. doi: 10.1074/jbc.M116.713818. Epub 2016 Jan 21.

8.

Revisiting cardiovascular calcification: A multifaceted disease requiring a multidisciplinary approach.

Hutcheson JD, Goettsch C, Rogers MA, Aikawa E.

Semin Cell Dev Biol. 2015 Oct;46:68-77. doi: 10.1016/j.semcdb.2015.09.004. Epub 2015 Sep 7. Review.

PMID:
26358815
9.

A Not-So-Little Role for Lipoprotein(a) in the Development of Calcific Aortic Valve Disease.

Rogers MA, Aikawa E.

Circulation. 2015 Aug 25;132(8):621-3. doi: 10.1161/CIRCULATIONAHA.115.018139. Epub 2015 Jul 29. No abstract available.

10.

Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum.

Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S.

J Biol Chem. 2015 Sep 25;290(39):23464-77. doi: 10.1074/jbc.M115.662668. Epub 2015 Jul 20.

11.

Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators.

Rogers MA, Liu J, Song BL, Li BL, Chang CC, Chang TY.

J Steroid Biochem Mol Biol. 2015 Jul;151:102-7. doi: 10.1016/j.jsbmb.2014.09.008. Epub 2014 Sep 12. Review.

12.

Modifying vascular calcification in diabetes mellitus: contribution of O-GlcNAcylation.

Rogers MA, Aikawa E.

Circ Res. 2014 Mar 28;114(7):1074-6. doi: 10.1161/CIRCRESAHA.114.303684. No abstract available.

13.

Medial and intimal calcification in chronic kidney disease: stressing the contributions.

Rogers M, Goettsch C, Aikawa E.

J Am Heart Assoc. 2013 Sep 23;2(5):e000481. doi: 10.1161/JAHA.113.000481. No abstract available.

14.

Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase.

Rogers MA, Liu J, Kushnir MM, Bryleva E, Rockwood AL, Meikle AW, Shapiro D, Vaisman BL, Remaley AT, Chang CC, Chang TY.

J Biol Chem. 2012 May 18;287(21):17483-92. doi: 10.1074/jbc.M111.331306. Epub 2012 Apr 2.

15.

A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations.

Maue RA, Burgess RW, Wang B, Wooley CM, Seburn KL, Vanier MT, Rogers MA, Chang CC, Chang TY, Harris BT, Graber DJ, Penatti CA, Porter DM, Szwergold BS, Henderson LP, Totenhagen JW, Trouard TP, Borbon IA, Erickson RP.

Hum Mol Genet. 2012 Feb 15;21(4):730-50. doi: 10.1093/hmg/ddr505. Epub 2011 Nov 2.

16.

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.

Bryleva EY, Rogers MA, Chang CC, Buen F, Harris BT, Rousselet E, Seidah NG, Oddo S, LaFerla FM, Spencer TA, Hickey WF, Chang TY.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3081-6. doi: 10.1073/pnas.0913828107. Epub 2010 Jan 26.

17.

Neuronal cholesterol esterification by ACAT1 in Alzheimer's disease.

Chang TY, Chang CC, Bryleva E, Rogers MA, Murphy SR.

IUBMB Life. 2010 Apr;62(4):261-7. doi: 10.1002/iub.305. Review.

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