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Items: 1 to 20 of 56

1.

Treatment pathway of bone sarcoma in children, adolescents, and young adults.

Reed DR, Hayashi M, Wagner L, Binitie O, Steppan DA, Brohl AS, Shinohara ET, Bridge JA, Loeb DM, Borinstein SC, Isakoff MS.

Cancer. 2017 Jun 15;123(12):2206-2218. doi: 10.1002/cncr.30589. Epub 2017 Mar 21. Review.

2.

Inhibiting DNA-PK<sub>CS</sub> radiosensitizes human osteosarcoma cells.

Mamo T, Mladek AC, Shogren KL, Gustafson C, Gupta SK, Riester SM, Maran A, Galindo M, van Wijnen AJ, Sarkaria JN, Yaszemski MJ.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):307-313. doi: 10.1016/j.bbrc.2017.03.033. Epub 2017 Mar 12.

PMID:
28300555
3.

Copy number analysis identifies tumor suppressive lncRNAs in human osteosarcoma.

Xie J, Lin D, Lee DH, Akunowicz J, Hansen M, Miller C, Sanada M, Kato M, Akagi T, Kawamata N, Ogawa S, Koeffler HP.

Int J Oncol. 2017 Mar;50(3):863-872. doi: 10.3892/ijo.2017.3864. Epub 2017 Jan 30.

PMID:
28197627
4.

DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.

Sheffield NC, Pierron G, Klughammer J, Datlinger P, Schönegger A, Schuster M, Hadler J, Surdez D, Guillemot D, Lapouble E, Freneaux P, Champigneulle J, Bouvier R, Walder D, Ambros IM, Hutter C, Sorz E, Amaral AT, de Álava E, Schallmoser K, Strunk D, Rinner B, Liegl-Atzwanger B, Huppertz B, Leithner A, de Pinieux G, Terrier P, Laurence V, Michon J, Ladenstein R, Holter W, Windhager R, Dirksen U, Ambros PF, Delattre O, Kovar H, Bock C, Tomazou EM.

Nat Med. 2017 Mar;23(3):386-395. doi: 10.1038/nm.4273. Epub 2017 Jan 30.

PMID:
28134926
5.

Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities.

Radic-Sarikas B, Tsafou KP, Emdal KB, Papamarkou T, Huber KV, Mutz C, Toretsky JA, Bennett KL, Olsen JV, Brunak S, Kovar H, Superti-Furga G.

Mol Cancer Ther. 2017 Jan;16(1):88-101. doi: 10.1158/1535-7163.MCT-16-0235. Epub 2016 Nov 15.

PMID:
28062706
6.

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis.

Hong SH, Tilan JU, Galli S, Acree R, Connors K, Mahajan A, Wietlisbach L, Polk T, Izycka-Swieszewska E, Lee YC, Cavalli LR, Rodriguez OC, Albanese C, Kitlinska JB.

J Vis Exp. 2016 Dec 9;(118). doi: 10.3791/54532.

PMID:
28060251
7.

Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness.

Galtsidis S, Logotheti S, Pavlopoulou A, Zampetidis CP, Papachristopoulou G, Scorilas A, Vojtesek B, Gorgoulis V, Zoumpourlis V.

Cancer Lett. 2017 Mar 1;388:96-106. doi: 10.1016/j.canlet.2016.11.036. Epub 2016 Dec 3.

PMID:
27919789
8.

Novel insights and therapeutic interventions for pediatric osteosarcoma.

Kager L, Tamamyan G, Bielack S.

Future Oncol. 2017 Feb;13(4):357-368. doi: 10.2217/fon-2016-0261. Epub 2016 Sep 21. Review.

PMID:
27651036
9.

IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma.

Lamhamedi-Cherradi SE, Menegaz BA, Ramamoorthy V, Vishwamitra D, Wang Y, Maywald RL, Buford AS, Fokt I, Skora S, Wang J, Naing A, Lazar AJ, Rohren EM, Daw NC, Subbiah V, Benjamin RS, Ratan R, Priebe W, Mikos AG, Amin HM, Ludwig JA.

J Natl Cancer Inst. 2016 Aug 30;108(12). pii: djw182. doi: 10.1093/jnci/djw182. Print 2016 Dec.

PMID:
27576731
10.

Defining Ewing and Ewing-like small round cell tumors (SRCT): The need for molecular techniques in their categorization and differential diagnosis. A study of 200 cases.

Machado I, Navarro L, Pellin A, Navarro S, Agaimy A, Tardío JC, Karseladze A, Petrov S, Scotlandi K, Picci P, Llombart-Bosch A.

Ann Diagn Pathol. 2016 Jun;22:25-32. doi: 10.1016/j.anndiagpath.2016.03.002. Epub 2016 Mar 14.

PMID:
27180056
11.

Ezrin Inhibition Up-regulates Stress Response Gene Expression.

Çelik H, Bulut G, Han J, Graham GT, Minas TZ, Conn EJ, Hong SH, Pauly GT, Hayran M, Li X, Özdemirli M, Ayhan A, Rudek MA, Toretsky JA, Üren A.

J Biol Chem. 2016 Jun 17;291(25):13257-70. doi: 10.1074/jbc.M116.718189. Epub 2016 May 2.

12.

Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1.

Fodor T, Szántó M, Abdul-Rahman O, Nagy L, Dér Á, Kiss B, Bai P.

PLoS One. 2016 Feb 26;11(2):e0150232. doi: 10.1371/journal.pone.0150232. eCollection 2016.

13.

Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma.

Fowles JS, Brown KC, Hess AM, Duval DL, Gustafson DL.

BMC Bioinformatics. 2016 Feb 19;17:93. doi: 10.1186/s12859-016-0942-8.

14.

Carcinosarcoma of the upper urinary tract with an aggressive angiosarcoma component.

Cuadra-Urteaga JL, Font A, Tapia G, Areal J, Taron M.

Cancer Biol Ther. 2016;17(3):233-6. doi: 10.1080/15384047.2016.1139237. Epub 2016 Feb 18.

15.

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.

Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, Lawlor E, Lessnick S, Ludwig J, Meltzer P, Metzler M, Mora J, Moriggl R, Nakamura T, Papamarkou T, Radic Sarikas B, Rédini F, Richter GH, Rossig C, Schadler K, Schäfer BW, Scotlandi K, Sheffield NC, Shelat A, Snaar-Jagalska E, Sorensen P, Stegmaier K, Stewart E, Sweet-Cordero A, Szuhai K, Tirado OM, Tirode F, Toretsky J, Tsafou K, Üren A, Zinovyev A, Delattre O.

Oncotarget. 2016 Feb 23;7(8):8613-24. doi: 10.18632/oncotarget.6937. Review.

16.

The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation.

Hesketh AJ, Maloney C, Behr CA, Edelman MC, Glick RD, Al-Abed Y, Symons M, Soffer SZ, Steinberg BM.

PLoS One. 2015 Dec 28;10(12):e0145197. doi: 10.1371/journal.pone.0145197. eCollection 2015.

17.

Clinical and biological significance of PIM1 kinase in osteosarcoma.

Liao Y, Feng Y, Shen J, Gao Y, Cote G, Choy E, Harmon D, Mankin H, Hornicek F, Duan Z.

J Orthop Res. 2016 Jul;34(7):1185-94. doi: 10.1002/jor.23134. Epub 2015 Dec 31.

18.

Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations.

Lorenz S, Barøy T, Sun J, Nome T, Vodák D, Bryne JC, Håkelien AM, Fernandez-Cuesta L, Möhlendick B, Rieder H, Szuhai K, Zaikova O, Ahlquist TC, Thomassen GO, Skotheim RI, Lothe RA, Tarpey PS, Campbell P, Flanagan A, Myklebost O, Meza-Zepeda LA.

Oncotarget. 2016 Feb 2;7(5):5273-88. doi: 10.18632/oncotarget.6567.

19.

Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency.

Kovac M, Blattmann C, Ribi S, Smida J, Mueller NS, Engert F, Castro-Giner F, Weischenfeldt J, Kovacova M, Krieg A, Andreou D, Tunn PU, Dürr HR, Rechl H, Schaser KD, Melcher I, Burdach S, Kulozik A, Specht K, Heinimann K, Fulda S, Bielack S, Jundt G, Tomlinson I, Korbel JO, Nathrath M, Baumhoer D.

Nat Commun. 2015 Dec 3;6:8940. doi: 10.1038/ncomms9940.

20.

Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma.

Wei Q, Tang YJ, Voisin V, Sato S, Hirata M, Whetstone H, Han I, Ailles L, Bader GD, Wunder J, Alman BA.

Oncotarget. 2015 Nov 24;6(37):40283-94. doi: 10.18632/oncotarget.5375.

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