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Items: 1 to 20 of 24

1.

Identification of cryptic subunits from an apicomplexan ATP synthase.

Huet D, Rajendran E, van Dooren GG, Lourido S.

Elife. 2018 Sep 11;7. pii: e38097. doi: 10.7554/eLife.38097.

2.

Toxoplasma CRISPR/Cas9 constructs are functional for gene disruption in Neospora caninum.

Arranz-SolĂ­s D, Regidor-Cerrillo J, Lourido S, Ortega-Mora LM, Saeij JPJ.

Int J Parasitol. 2018 Jul;48(8):597-600. doi: 10.1016/j.ijpara.2018.03.002. Epub 2018 Apr 3.

PMID:
29625127
3.

Identification of PNG kinase substrates uncovers interactions with the translational repressor TRAL in the oocyte-to-embryo transition.

Hara M, Lourido S, Petrova B, Lou HJ, Von Stetina JR, Kashevsky H, Turk BE, Orr-Weaver TL.

Elife. 2018 Feb 26;7. pii: e33150. doi: 10.7554/eLife.33150.

4.

CRISPR-Cas9-based genome-wide screening of Toxoplasma gondii.

Sidik SM, Huet D, Lourido S.

Nat Protoc. 2018 Jan;13(1):307-323. doi: 10.1038/nprot.2017.131. Epub 2018 Jan 11.

PMID:
29323662
5.

O-fucosylated glycoproteins form assemblies in close proximity to the nuclear pore complexes of Toxoplasma gondii.

Bandini G, Haserick JR, Motari E, Ouologuem DT, Lourido S, Roos DS, Costello CE, Robbins PW, Samuelson J.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11567-11572. Epub 2016 Sep 23.

6.

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.

Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JPJ, Carruthers VB, Niles JC, Lourido S.

Cell. 2016 Sep 8;166(6):1423-1435.e12. doi: 10.1016/j.cell.2016.08.019. Epub 2016 Sep 2.

7.

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose.

Chahal JS, Khan OF, Cooper CL, McPartlan JS, Tsosie JK, Tilley LD, Sidik SM, Lourido S, Langer R, Bavari S, Ploegh HL, Anderson DG.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4133-42. doi: 10.1073/pnas.1600299113. Epub 2016 Jul 5. Erratum in: Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5250.

8.

Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii.

Brown KM, Lourido S, Sibley LD.

J Biol Chem. 2016 Apr 29;291(18):9554-65. doi: 10.1074/jbc.M115.700518. Epub 2016 Mar 1.

9.

Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling.

Sidik SM, Hortua Triana MA, Paul AS, El Bakkouri M, Hackett CG, Tran F, Westwood NJ, Hui R, Zuercher WJ, Duraisingh MT, Moreno SN, Lourido S.

J Biol Chem. 2016 Apr 29;291(18):9566-80. doi: 10.1074/jbc.M115.703546. Epub 2016 Mar 1.

10.

Identification of Direct Kinase Substrates Using Analogue-Sensitive Alleles.

Rothenberg DA, Gordon EA, White FM, Lourido S.

Methods Mol Biol. 2016;1355:71-84. doi: 10.1007/978-1-4939-3049-4_5.

PMID:
26584919
11.

Allosteric activation of apicomplexan calcium-dependent protein kinases.

Ingram JR, Knockenhauer KE, Markus BM, Mandelbaum J, Ramek A, Shan Y, Shaw DE, Schwartz TU, Ploegh HL, Lourido S.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):E4975-84. doi: 10.1073/pnas.1505914112. Epub 2015 Aug 24.

12.

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.

Gold DA, Kaplan AD, Lis A, Bett GC, Rosowski EE, Cirelli KM, Bougdour A, Sidik SM, Beck JR, Lourido S, Egea PF, Bradley PJ, Hakimi MA, Rasmusson RL, Saeij JP.

Cell Host Microbe. 2015 May 13;17(5):642-52. doi: 10.1016/j.chom.2015.04.003.

13.

The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp.

Lourido S, Moreno SN.

Cell Calcium. 2015 Mar;57(3):186-93. doi: 10.1016/j.ceca.2014.12.010. Epub 2014 Dec 31. Review.

14.

One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism.

Swee LK, Lourido S, Bell GW, Ingram JR, Ploegh HL.

ACS Chem Biol. 2015 Feb 20;10(2):460-5. doi: 10.1021/cb500462t. Epub 2014 Nov 10.

15.

Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9.

Sidik SM, Hackett CG, Tran F, Westwood NJ, Lourido S.

PLoS One. 2014 Jun 27;9(6):e100450. doi: 10.1371/journal.pone.0100450. eCollection 2014.

16.

Exploiting the unique ATP-binding pocket of toxoplasma calcium-dependent protein kinase 1 to identify its substrates.

Lourido S, Jeschke GR, Turk BE, Sibley LD.

ACS Chem Biol. 2013;8(6):1155-62. doi: 10.1021/cb400115y. Epub 2013 Apr 10.

17.

Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii.

Lourido S, Zhang C, Lopez MS, Tang K, Barks J, Wang Q, Wildman SA, Shokat KM, Sibley LD.

J Med Chem. 2013 Apr 11;56(7):3068-77. doi: 10.1021/jm4001314. Epub 2013 Mar 26.

18.

Distinct signalling pathways control Toxoplasma egress and host-cell invasion.

Lourido S, Tang K, Sibley LD.

EMBO J. 2012 Dec 12;31(24):4524-34. doi: 10.1038/emboj.2012.299. Epub 2012 Nov 13.

19.

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma.

Lourido S, Shuman J, Zhang C, Shokat KM, Hui R, Sibley LD.

Nature. 2010 May 20;465(7296):359-62. doi: 10.1038/nature09022.

20.

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium.

Wernimont AK, Artz JD, Finerty P Jr, Lin YH, Amani M, Allali-Hassani A, Senisterra G, Vedadi M, Tempel W, Mackenzie F, Chau I, Lourido S, Sibley LD, Hui R.

Nat Struct Mol Biol. 2010 May;17(5):596-601. doi: 10.1038/nsmb.1795. Epub 2010 May 2.

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