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Items: 1 to 20 of 83


Acquired PIK3CA amplification causes resistance to selective phosphoinositide 3-kinase inhibitors in breast cancer.

Huw LY, O'Brien C, Pandita A, Mohan S, Spoerke JM, Lu S, Wang Y, Hampton GM, Wilson TR, Lackner MR.

Oncogenesis. 2013 Dec 23;2:e83. doi: 10.1038/oncsis.2013.46.


Mitochondrial DNA depletion sensitizes cancer cells to PARP inhibitors by translational and post-translational repression of BRCA2.

Arbini AA, Guerra F, Greco M, Marra E, Gandee L, Xiao G, Lotan Y, Gasparre G, Hsieh JT, Moro L.

Oncogenesis. 2013 Dec 16;2:e82. doi: 10.1038/oncsis.2013.45.


Protein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models.

Peng M, Ball-Kell SM, Franks RR, Xie H, Tyner AL.

Oncogenesis. 2013 Dec 9;2:e81. doi: 10.1038/oncsis.2013.43.


A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1-MMP.

Shiryaev SA, Remacle AG, Golubkov VS, Ingvarsen S, Porse A, Behrendt N, Cieplak P, Strongin AY.

Oncogenesis. 2013 Dec 2;2:e80. doi: 10.1038/oncsis.2013.44.


Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways.

Stellzig J, Chariot A, Shostak K, Ismail Göktuna S, Renner F, Acker T, Pagenstecher A, Schmitz ML.

Oncogenesis. 2013 Nov 11;2:e79. doi: 10.1038/oncsis.2013.42.


Runx1 deficiency permits granulocyte lineage commitment but impairs subsequent maturation.

Ng KP, Hu Z, Ebrahem Q, Negrotto S, Lausen J, Saunthararajah Y.

Oncogenesis. 2013 Nov 4;2:e78. doi: 10.1038/oncsis.2013.41.


The histone variant MacroH2A regulates Ca(2+) influx through TRPC3 and TRPC6 channels.

Kim JM, Heo K, Choi J, Kim K, An W.

Oncogenesis. 2013 Oct 28;2:e77. doi: 10.1038/oncsis.2013.40.


Deregulation of let-7e in epithelial ovarian cancer promotes the development of resistance to cisplatin.

Cai J, Yang C, Yang Q, Ding H, Jia J, Guo J, Wang J, Wang Z.

Oncogenesis. 2013 Oct 7;2:e75. doi: 10.1038/oncsis.2013.39.


Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R.

Meyer DS, Koren S, Leroy C, Brinkhaus H, Müller U, Klebba I, Müller M, Cardiff RD, Bentires-Alj M.

Oncogenesis. 2013 Sep 30;2:e74. doi: 10.1038/oncsis.2013.38.


Suppression of SCARA5 by Snail1 is essential for EMT-associated cell migration of A549 cells.

Liu J, Hu G, Chen D, Gong AY, Soori GS, Dobleman TJ, Chen XM.

Oncogenesis. 2013 Sep 23;2:e73. doi: 10.1038/oncsis.2013.37.


Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo.

Manente AG, Valenti D, Pinton G, Jithesh PV, Daga A, Rossi L, Gray SG, O'Byrne KJ, Fennell DA, Vacca RA, Nilsson S, Mutti L, Moro L.

Oncogenesis. 2013 Sep 23;2:e72. doi: 10.1038/oncsis.2013.32.


Epigenetic and genetic features of 24 colon cancer cell lines.

Ahmed D, Eide PW, Eilertsen IA, Danielsen SA, Eknæs M, Hektoen M, Lind GE, Lothe RA.

Oncogenesis. 2013 Sep 16;2:e71. doi: 10.1038/oncsis.2013.35.


Protooncogene TCL1b functions as an Akt kinase co-activator that exhibits oncogenic potency in vivo.

Hashimoto M, Suizu F, Tokuyama W, Noguchi H, Hirata N, Matsuda-Lennikov M, Edamura T, Masuzawa M, Gotoh N, Tanaka S, Noguchi M.

Oncogenesis. 2013 Sep 16;2:e70. doi: 10.1038/oncsis.2013.30.


Centrosomal kinase Nek2 cooperates with oncogenic pathways to promote metastasis.

Das TK, Dana D, Paroly SS, Perumal SK, Singh S, Jhun H, Pendse J, Cagan RL, Talele TT, Kumar S.

Oncogenesis. 2013 Sep 9;2:e69. doi: 10.1038/oncsis.2013.34.


A novel orthotopic mouse model of head and neck cancer and lymph node metastasis.

Masood R, Hochstim C, Cervenka B, Zu S, Baniwal SK, Patel V, Kobielak A, Sinha UK.

Oncogenesis. 2013 Sep 9;2:e68. doi: 10.1038/oncsis.2013.33.


T antigen transformation reveals Tp53/RB-dependent route to PLAC1 transcription activation in primary fibroblasts.

Chen Y, Schlessinger D, Nagaraja R.

Oncogenesis. 2013 Sep 2;2:e67. doi: 10.1038/oncsis.2013.31.


Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug.

Tamminen JA, Parviainen V, Rönty M, Wohl AP, Murray L, Joenväärä S, Varjosalo M, Leppäranta O, Ritvos O, Sengle G, Renkonen R, Myllärniemi M, Koli K.

Oncogenesis. 2013 Aug 26;2:e66. doi: 10.1038/oncsis.2013.29.


Binding of αvβ1 and αvβ6 integrins to tenascin-C induces epithelial-mesenchymal transition-like change of breast cancer cells.

Katoh D, Nagaharu K, Shimojo N, Hanamura N, Yamashita M, Kozuka Y, Imanaka-Yoshida K, Yoshida T.

Oncogenesis. 2013 Aug 19;2:e65. doi: 10.1038/oncsis.2013.27.


Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling.

Jung H, Kim BG, Han WH, Lee JH, Cho JY, Park WS, Maurice MM, Han JK, Lee MJ, Finley D, Jho EH.

Oncogenesis. 2013 Aug 19;2:e64. doi: 10.1038/oncsis.2013.28.

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