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Items: 1 to 20 of 1122


Cardiovascular Ion Channel Inhibitor Drug-Drug Interactions with P-glycoprotein.

Ledwitch KV, Roberts AG.

AAPS J. 2017 Mar;19(2):409-420. doi: 10.1208/s12248-016-0023-y. Epub 2016 Dec 27. Review.


Intra-articular Injection of Urinary Bladder Matrix Reduces Osteoarthritis Development.

Jacobs HN, Rathod S, Wolf MT, Elisseeff JH.

AAPS J. 2017 Jan;19(1):141-149. doi: 10.1208/s12248-016-9999-6. Epub 2016 Oct 24. Erratum in: AAPS J. 2017 Mar;19(2):595.


Bone Regeneration Using Gene-Activated Matrices.

D'Mello S, Atluri K, Geary SM, Hong L, Elangovan S, Salem AK.

AAPS J. 2017 Jan;19(1):43-53. doi: 10.1208/s12248-016-9982-2. Epub 2016 Sep 21. Review.


Optimal Design for Informative Protocols in Xenograft Tumor Growth Inhibition Experiments in Mice.

Lestini G, Mentré F, Magni P.

AAPS J. 2016 Sep;18(5):1233-1243. doi: 10.1208/s12248-016-9924-z. Epub 2016 Jun 15.


Multiscale Modeling of Antibody-Drug Conjugates: Connecting Tissue and Cellular Distribution to Whole Animal Pharmacokinetics and Potential Implications for Efficacy.

Cilliers C, Guo H, Liao J, Christodolu N, Thurber GM.

AAPS J. 2016 Sep;18(5):1117-1130. doi: 10.1208/s12248-016-9940-z. Epub 2016 Jun 10.


How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder?

Zhou QT, Loh ZH, Yu J, Sun SP, Gengenbach T, Denman JA, Li J, Chan HK.

AAPS J. 2016 Sep;18(5):1213-1224. doi: 10.1208/s12248-016-9934-x. Epub 2016 Jun 2.


A Novel Physiology-Based Mathematical Model to Estimate Red Blood Cell Lifespan in Different Human Age Groups.

An G, Widness JA, Mock DM, Veng-Pedersen P.

AAPS J. 2016 Sep;18(5):1182-1191. doi: 10.1208/s12248-016-9923-0. Epub 2016 May 23.


The FDA's Experience with Emerging Genomics Technologies-Past, Present, and Future.

Xu J, Thakkar S, Gong B, Tong W.

AAPS J. 2016 Jul;18(4):814-8. doi: 10.1208/s12248-016-9917-y. Epub 2016 Apr 26. Review.


Effect of Gastric Fluid Volume on the In Vitro Dissolution and In Vivo Absorption of BCS Class II Drugs: a Case Study with Nifedipine.

Nader AM, Quinney SK, Fadda HM, Foster DR.

AAPS J. 2016 Jul;18(4):981-8. doi: 10.1208/s12248-016-9918-x. Epub 2016 Apr 22.


A Kinetic Degradation Study of Curcumin in Its Free Form and Loaded in Polymeric Micelles.

Naksuriya O, van Steenbergen MJ, Torano JS, Okonogi S, Hennink WE.

AAPS J. 2016 May;18(3):777-87. doi: 10.1208/s12248-015-9863-0. Epub 2016 Apr 1.


Evolution of Antibody-Drug Conjugate Tumor Disposition Model to Predict Preclinical Tumor Pharmacokinetics of Trastuzumab-Emtansine (T-DM1).

Singh AP, Maass KF, Betts AM, Wittrup KD, Kulkarni C, King LE, Khot A, Shah DK.

AAPS J. 2016 Jul;18(4):861-75. doi: 10.1208/s12248-016-9904-3. Epub 2016 Mar 30.


Recent Advances in Application of Pharmacogenomics for Biotherapeutics.

Mahajan PB.

AAPS J. 2016 May;18(3):605-11. doi: 10.1208/s12248-016-9903-4. Epub 2016 Mar 23. Review.


RGS6 as a Novel Therapeutic Target in CNS Diseases and Cancer.

Ahlers KE, Chakravarti B, Fisher RA.

AAPS J. 2016 May;18(3):560-72. doi: 10.1208/s12248-016-9899-9. Epub 2016 Mar 22. Review.


Multi-Functional Diarylurea Small Molecule Inhibitors of TRPV1 with Therapeutic Potential for Neuroinflammation.

Feng Z, Pearce LV, Zhang Y, Xing C, Herold BK, Ma S, Hu Z, Turcios NA, Yang P, Tong Q, McCall AK, Blumberg PM, Xie XQ.

AAPS J. 2016 Jul;18(4):898-913. doi: 10.1208/s12248-016-9888-z. Epub 2016 Mar 21.


Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway.

Hong B, Su Z, Zhang C, Yang Y, Guo Y, Li W, Kong AN.

AAPS J. 2016 May;18(3):659-69. doi: 10.1208/s12248-016-9901-6. Epub 2016 Mar 17.


Tissue Penetration of a Novel Spectinamide Antibiotic for the Treatment of Tuberculosis.

Madhura DB, Trivedi A, Liu J, Boyd VA, Jeffries C, Loveless V, Lee RE, Meibohm B.

AAPS J. 2016 May;18(3):788-91. doi: 10.1208/s12248-016-9900-7. Epub 2016 Mar 16.


Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.

Jones CR, Hatley OJ, Ungell AL, Hilgendorf C, Peters SA, Rostami-Hodjegan A.

AAPS J. 2016 May;18(3):589-604. doi: 10.1208/s12248-016-9889-y. Epub 2016 Mar 10. Review.


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