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Items: 1 to 20 of 61


RBM17 Interacts with U2SURP and CHERP to Regulate Expression and Splicing of RNA-Processing Proteins.

De Maio A, Yalamanchili HK, Adamski CJ, Gennarino VA, Liu Z, Qin J, Jung SY, Richman R, Orr H, Zoghbi HY.

Cell Rep. 2018 Oct 16;25(3):726-736.e7. doi: 10.1016/j.celrep.2018.09.041.


A druggable genome screen identifies modifiers of α-synuclein levels via a tiered cross-species validation approach.

Rousseaux MWC, Vázquez-Vélez GE, Al-Ramahi I, Jeong HH, Bajic A, Revelli JP, Ye H, Phan ET, Deger JM, Perez AM, Kim JY, Lavery LA, Xu Q, Li MZ, Kang H, Kim JJ, Shulman JM, Westbrook TF, Elledge SJ, Liu Z, Botas J, Zoghbi HY.

J Neurosci. 2018 Sep 24. pii: 0254-18. doi: 10.1523/JNEUROSCI.0254-18.2018. [Epub ahead of print]


Synthesis and biological evaluation of novel tricyclic matrinic derivatives as potential anti-filovirus agents.

Zhang X, Liu Q, Li Q, Li Y, Liu Z, Deng H, Tang S, Wang Y, Wang Y, Song D.

Acta Pharm Sin B. 2018 Jul;8(4):629-638. doi: 10.1016/j.apsb.2018.01.006. Epub 2018 Feb 21.


TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.

Martini-Stoica H, Cole AL, Swartzlander DB, Chen F, Wan YW, Bajaj L, Bader DA, Lee VMY, Trojanowski JQ, Liu Z, Sardiello M, Zheng H.

J Exp Med. 2018 Sep 3;215(9):2355-2377. doi: 10.1084/jem.20172158. Epub 2018 Aug 14.


Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations.

Raman AT, Pohodich AE, Wan YW, Yalamanchili HK, Lowry WE, Zoghbi HY, Liu Z.

Nat Commun. 2018 Aug 13;9(1):3225. doi: 10.1038/s41467-018-05627-1.


High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration.

Al-Ramahi I, Lu B, Di Paola S, Pang K, de Haro M, Peluso I, Gallego-Flores T, Malik NT, Erikson K, Bleiberg BA, Avalos M, Fan G, Rivers LE, Laitman AM, Diaz-García JR, Hild M, Palacino J, Liu Z, Medina DL, Botas J.

Cell Syst. 2018 Jul 25;7(1):28-40.e4. doi: 10.1016/j.cels.2018.05.010. Epub 2018 Jun 20.


Tau Activates Transposable Elements in Alzheimer's Disease.

Guo C, Jeong HH, Hsieh YC, Klein HU, Bennett DA, De Jager PL, Liu Z, Shulman JM.

Cell Rep. 2018 Jun 5;23(10):2874-2880. doi: 10.1016/j.celrep.2018.05.004.


Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila.

Ma Z, Wang H, Cai Y, Wang H, Niu K, Wu X, Ma H, Yang Y, Tong W, Liu F, Liu Z, Zhang Y, Liu R, Zhu ZJ, Liu N.

Elife. 2018 May 29;7. pii: e35368. doi: 10.7554/eLife.35368.


Genome-wide distribution of linker histone H1.0 is independent of MeCP2.

Ito-Ishida A, Yamalanchili HK, Shao Y, Baker SA, Heckman LD, Lavery LA, Kim JY, Lombardi LM, Sun Y, Liu Z, Zoghbi HY.

Nat Neurosci. 2018 Jun;21(6):794-798. doi: 10.1038/s41593-018-0155-8. Epub 2018 May 25.


Detecting hidden batch factors through data-adaptive adjustment for biological effects.

Yi H, Raman AT, Zhang H, Allen GI, Liu Z.

Bioinformatics. 2018 Apr 1;34(7):1141-1147. doi: 10.1093/bioinformatics/btx635.


Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity.

Pohodich AE, Yalamanchili H, Raman AT, Wan YW, Gundry M, Hao S, Jin H, Tang J, Liu Z, Zoghbi HY.

Elife. 2018 Mar 23;7. pii: e34031. doi: 10.7554/eLife.34031.


ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.

Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT.

Neuron. 2018 Mar 21;97(6):1235-1243.e5. doi: 10.1016/j.neuron.2018.02.013. Epub 2018 Mar 8.


Simple Assessment of Nitrogen Nutrition Index in Summer Maize by Using Chlorophyll Meter Readings.

Zhao B, Ata-Ul-Karim ST, Liu Z, Zhang J, Xiao J, Liu Z, Qin A, Ning D, Yang Q, Zhang Y, Duan A.

Front Plant Sci. 2018 Jan 19;9:11. doi: 10.3389/fpls.2018.00011. eCollection 2018.


Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome.

Yin J, Chen W, Chao ES, Soriano S, Wang L, Wang W, Cummock SE, Tao H, Pang K, Liu Z, Pereira FA, Samaco RC, Zoghbi HY, Xue M, Schaaf CP.

Am J Hum Genet. 2018 Feb 1;102(2):296-308. doi: 10.1016/j.ajhg.2018.01.005.


Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.

Tan Q, Brunetti L, Rousseaux MWC, Lu HC, Wan YW, Revelli JP, Liu Z, Goodell MA, Zoghbi HY.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1511-E1519. doi: 10.1073/pnas.1716452115. Epub 2018 Jan 30.


POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain.

McClard CK, Kochukov MY, Herman I, Liu Z, Eblimit A, Moayedi Y, Ortiz-Guzman J, Colchado D, Pekarek B, Panneerselvam S, Mardon G, Arenkiel BR.

J Neurosci. 2018 Feb 7;38(6):1443-1461. doi: 10.1523/JNEUROSCI.1641-17.2017. Epub 2018 Jan 5.


An ultra-fast and scalable quantification pipeline for transposable elements from next generation sequencing data.

Jeong HH, Yalamanchili HK, Guo C, Shulman JM, Liu Z.

Pac Symp Biocomput. 2018;23:168-179.


The International Conference on Intelligent Biology and Medicine (ICIBM) 2016: summary and innovation in genomics.

Zhao Z, Liu Z, Chen K, Guo Y, Allen GI, Zhang J, Jim Zheng W, Ruan J.

BMC Genomics. 2017 Oct 3;18(Suppl 6):703. doi: 10.1186/s12864-017-4018-6.


The International Conference on Intelligent Biology and Medicine (ICIBM) 2016: from big data to big analytical tools.

Liu Z, Zheng WJ, Allen GI, Liu Y, Ruan J, Zhao Z.

BMC Bioinformatics. 2017 Oct 3;18(Suppl 11):405. doi: 10.1186/s12859-017-1797-3.


Data Analysis Pipeline for RNA-seq Experiments: From Differential Expression to Cryptic Splicing.

Yalamanchili HK, Wan YW, Liu Z.

Curr Protoc Bioinformatics. 2017 Sep 13;59:11.15.1-11.15.21. doi: 10.1002/cpbi.33.


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