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Items: 12


Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance.

Chen K, Jih A, Kavaler ST, Lagakos WS, Oh D, Watkins SM, Kim JJ.

Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E293-301. doi: 10.1152/ajpendo.00045.2015. Epub 2015 Jun 9. Erratum in: Am J Physiol Endocrinol Metab. 2016 Feb 15;310(4):E301.


LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.

Li P, Oh DY, Bandyopadhyay G, Lagakos WS, Talukdar S, Osborn O, Johnson A, Chung H, Maris M, Ofrecio JM, Taguchi S, Lu M, Olefsky JM.

Nat Med. 2015 Mar;21(3):239-247. doi: 10.1038/nm.3800. Epub 2015 Feb 23.


A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.

Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JG, Olefsky JM.

Nat Med. 2014 Aug;20(8):942-7. doi: 10.1038/nm.3614. Epub 2014 Jul 6.


NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids.

Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM.

Cell. 2013 Sep 26;155(1):200-214. doi: 10.1016/j.cell.2013.08.054.


Liver fatty acid-binding protein binds monoacylglycerol in vitro and in mouse liver cytosol.

Lagakos WS, Guan X, Ho SY, Sawicki LR, Corsico B, Kodukula S, Murota K, Stark RE, Storch J.

J Biol Chem. 2013 Jul 5;288(27):19805-15. doi: 10.1074/jbc.M113.473579. Epub 2013 May 8.


Liver-specific p70 S6 kinase depletion protects against hepatic steatosis and systemic insulin resistance.

Bae EJ, Xu J, Oh DY, Bandyopadhyay G, Lagakos WS, Keshwani M, Olefsky JM.

J Biol Chem. 2012 May 25;287(22):18769-80. doi: 10.1074/jbc.M112.365544. Epub 2012 Apr 9.


The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity.

Oh DY, Lagakos WS.

Curr Opin Clin Nutr Metab Care. 2011 Jul;14(4):322-7. doi: 10.1097/MCO.0b013e3283479230. Review.


Different functions of intestinal and liver-type fatty acid-binding proteins in intestine and in whole body energy homeostasis.

Lagakos WS, Gajda AM, Agellon L, Binas B, Choi V, Mandap B, Russnak T, Zhou YX, Storch J.

Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G803-14. doi: 10.1152/ajpgi.00229.2010. Epub 2011 Feb 24.


Developmental changes in the concentrations of glutamine and other amino acids in plasma and skeletal muscle of the Standardbred foal.

Manso Filho HC, McKeever KH, Gordon ME, Manso HE, Lagakos WS, Wu G, Watford M.

J Anim Sci. 2009 Aug;87(8):2528-35. doi: 10.2527/jas.2009-1845. Epub 2009 Apr 24.


Changes in glutamine metabolism indicate a mild catabolic state in the transition mare.

Manso Filho HC, McKeever KH, Gordon ME, Costa HE, Lagakos WS, Watford M.

J Anim Sci. 2008 Dec;86(12):3424-31. doi: 10.2527/jas.2008-1054. Erratum in: J Anim Sci. 2009 Jan;87(1):455.


Metabolism of apical versus basolateral sn-2-monoacylglycerol and fatty acids in rodent small intestine.

Storch J, Zhou YX, Lagakos WS.

J Lipid Res. 2008 Aug;49(8):1762-9. doi: 10.1194/jlr.M800116-JLR200. Epub 2008 Apr 17.


Liver fatty acid-binding protein initiates budding of pre-chylomicron transport vesicles from intestinal endoplasmic reticulum.

Neeli I, Siddiqi SA, Siddiqi S, Mahan J, Lagakos WS, Binas B, Gheyi T, Storch J, Mansbach CM 2nd.

J Biol Chem. 2007 Jun 22;282(25):17974-84. Epub 2007 Apr 20.

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