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Items: 1 to 20 of 142

1.

PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores.

Chen LM, Yao N, Garg E, Zhu Y, Nguyen TTT, Pokhvisneva I, Hari Dass SA, Unternaehrer E, Gaudreau H, Forest M, McEwen LM, MacIsaac JL, Kobor MS, Greenwood CMT, Silveira PP, Meaney MJ, O'Donnell KJ.

BMC Bioinformatics. 2018 Aug 8;19(1):295. doi: 10.1186/s12859-018-2289-9.

2.

Variability in DNA methylation at the serotonin transporter gene promoter: epigenetic mechanism or cell-type artifact?

Moore SR, Kobor MS.

Mol Psychiatry. 2018 Aug 6. doi: 10.1038/s41380-018-0121-6. [Epub ahead of print] No abstract available.

PMID:
30082839
3.

An epigenetic pathway approach to investigating associations between prenatal exposure to maternal mood disorder and newborn neurobehavior.

Conradt E, Adkins DE, Crowell SE, Monk C, Kobor MS.

Dev Psychopathol. 2018 Aug;30(3):881-890. doi: 10.1017/S0954579418000688.

4.

The early care environment and DNA methylome variation in childhood.

Garg E, Chen L, Nguyen TTT, Pokhvisneva I, Chen LM, Unternaehrer E, MacIsaac JL, McEwen LM, Mah SM, Gaudreau H, Levitan R, Moss E, Sokolowski MB, Kennedy JL, Steiner MS, Meaney MJ, Holbrook JD, Silveira PP, Karnani N, Kobor MS, O'Donnell KJ; Mavan Study Team.

Dev Psychopathol. 2018 Aug;30(3):891-903. doi: 10.1017/S0954579418000627.

PMID:
30068421
5.

Comparison of DNA methylation measured by Illumina 450K and EPIC BeadChips in blood of newborns and 14-year-old children.

Solomon O, MacIsaac J, Quach H, Tindula G, Kobor MS, Huen K, Meaney MJ, Eskenazi B, Barcellos LF, Holland N.

Epigenetics. 2018 Aug 15:1-10. doi: 10.1080/15592294.2018.1497386. [Epub ahead of print]

PMID:
30044683
6.

Reproduction predicts shorter telomeres and epigenetic age acceleration among young adult women.

Ryan CP, Hayes MG, Lee NR, McDade TW, Jones MJ, Kobor MS, Kuzawa CW, Eisenberg DTA.

Sci Rep. 2018 Jul 23;8(1):11100. doi: 10.1038/s41598-018-29486-4.

7.

Early-life socioeconomic disadvantage, not current, predicts accelerated epigenetic aging of monocytes.

Austin MK, Chen E, Ross KM, McEwen LM, Maclsaac JL, Kobor MS, Miller GE.

Psychoneuroendocrinology. 2018 Jul 5;97:131-134. doi: 10.1016/j.psyneuen.2018.07.007. [Epub ahead of print]

PMID:
30016711
8.

Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents.

Horvath S, Stein DJ, Phillips N, Heany SJ, Kobor MS, Lin DTS, Myer L, Zar HJ, Levine AJ, Hoare J.

AIDS. 2018 Jul 17;32(11):1465-1474. doi: 10.1097/QAD.0000000000001854.

PMID:
29746298
9.

Cysteinyl Leukotriene Receptor 1 and Health Effects of Particulate Exposure in Asthma.

Rabinovitch N, Jones MJ, Faino A, Strand M, Morin AM, MacIsaac J, Reynolds PR, Singh A, Kobor MS, Gelfand EW, Carlsten C.

Ann Am Thorac Soc. 2018 Apr;15(Supplement_2):S129. doi: 10.1513/AnnalsATS.201706-469MG.

PMID:
29676619
10.

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.

Clifford RL, Fishbane N, Patel J, MacIsaac JL, McEwen LM, Fisher AJ, Brandsma CA, Nair P, Kobor MS, Hackett TL, Knox AJ.

Clin Epigenetics. 2018 Mar 5;10:32. doi: 10.1186/s13148-018-0464-5. eCollection 2018.

11.

Epigenetic analysis of human postmortem brain tissue.

Islam SA, Lussier AA, Kobor MS.

Handb Clin Neurol. 2018;150:237-261. doi: 10.1016/B978-0-444-63639-3.00017-7. Review.

PMID:
29496144
12.

Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time.

Forest M, O'Donnell KJ, Voisin G, Gaudreau H, MacIsaac JL, McEwen LM, Silveira PP, Steiner M, Kobor MS, Meaney MJ, Greenwood CMT.

Epigenetics. 2018;13(1):19-32. doi: 10.1080/15592294.2017.1411443. Epub 2018 Jan 30.

13.

Healthy Foundations Study: a randomised controlled trial to evaluate biological embedding of early-life experiences.

Gonzalez A, Catherine N, Boyle M, Jack SM, Atkinson L, Kobor M, Sheehan D, Tonmyr L, Waddell C, MacMillan HL; Healthy Foundations Study Team.

BMJ Open. 2018 Jan 26;8(1):e018915. doi: 10.1136/bmjopen-2017-018915.

14.

DNA methylation as a predictor of fetal alcohol spectrum disorder.

Lussier AA, Morin AM, MacIsaac JL, Salmon J, Weinberg J, Reynolds JN, Pavlidis P, Chudley AE, Kobor MS.

Clin Epigenetics. 2018 Jan 12;10:5. doi: 10.1186/s13148-018-0439-6. eCollection 2018.

15.

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up.

O'Donnell KJ, Chen L, MacIsaac JL, McEwen LM, Nguyen T, Beckmann K, Zhu Y, Chen LM, Brooks-Gunn J, Goldman D, Grigorenko EL, Leckman JF, Diorio J, Karnani N, Olds DL, Holbrook JD, Kobor MS, Meaney MJ.

Transl Psychiatry. 2018 Jan 10;8(1):15. doi: 10.1038/s41398-017-0063-9.

16.

Choice of surrogate tissue influences neonatal EWAS findings.

Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N.

BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x.

17.

Worldwide patterns of human epigenetic variation.

Carja O, MacIsaac JL, Mah SM, Henn BM, Kobor MS, Feldman MW, Fraser HB.

Nat Ecol Evol. 2017 Oct;1(10):1577-1583. doi: 10.1038/s41559-017-0299-z. Epub 2017 Aug 28.

PMID:
29185505
18.

Epigenetic correlates of neonatal contact in humans.

Moore SR, McEwen LM, Quirt J, Morin A, Mah SM, Barr RG, Boyce WT, Kobor MS.

Dev Psychopathol. 2017 Dec;29(5):1517-1538. doi: 10.1017/S0954579417001213.

PMID:
29162165
19.

DNA methylation signatures in peripheral blood mononuclear cells from a lifestyle intervention for women at midlife: a pilot randomized controlled trial.

McEwen LM, Gatev EG, Jones MJ, MacIsaac JL, McAllister MM, Goulding RE, Madden KM, Dawes MG, Kobor MS, Ashe MC.

Appl Physiol Nutr Metab. 2018 Mar;43(3):233-239. doi: 10.1139/apnm-2017-0436. Epub 2017 Oct 19.

PMID:
29049890
20.

RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability.

Chang EY, Novoa CA, Aristizabal MJ, Coulombe Y, Segovia R, Chaturvedi R, Shen Y, Keong C, Tam AS, Jones SJM, Masson JY, Kobor MS, Stirling PC.

J Cell Biol. 2017 Dec 4;216(12):3991-4005. doi: 10.1083/jcb.201703168. Epub 2017 Oct 17.

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