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Items: 1 to 20 of 357

1.

Targeting amyloid clearance in Alzheimer's disease as a therapeutic strategy.

Nalivaeva NN, Turner AJ.

Br J Pharmacol. 2019 Feb 2. doi: 10.1111/bph.14593. [Epub ahead of print] Review.

PMID:
30710367
2.

French maritime pine bark treatment decelerates plaque development and improves spatial memory in Alzheimer's disease mice.

Paarmann K, Prakash SR, Krohn M, Möhle L, Brackhan M, Brüning T, Eiriz I, Pahnke J.

Phytomedicine. 2018 Nov 29;57:39-48. doi: 10.1016/j.phymed.2018.11.033. [Epub ahead of print]

PMID:
30668321
3.

Insulin signaling in Drosophila melanogaster mediates Aβ toxicity.

Huang Y, Wan Z, Wang Z, Zhou B.

Commun Biol. 2019 Jan 8;2:13. doi: 10.1038/s42003-018-0253-x. eCollection 2019.

4.

27-hydroxycholesterol promotes Aβ accumulation via altering Aβ metabolism in mild cognitive impairment patients and APP/PS1 mice.

Zhang X, Xi Y, Yu H, An Y, Wang Y, Tao L, Wang Y, Liu W, Wang T, Xiao R.

Brain Pathol. 2018 Dec 23. doi: 10.1111/bpa.12698. [Epub ahead of print]

PMID:
30582229
5.

Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues.

Kulas JA, Franklin WF, Smith NA, Manocha GD, Puig KL, Nagamoto-Combs K, Hendrix RD, Taglialatela G, Barger SW, Combs CK.

Am J Physiol Endocrinol Metab. 2019 Jan 1;316(1):E106-E120. doi: 10.1152/ajpendo.00279.2018. Epub 2018 Nov 13. Erratum in: Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E345.

PMID:
30422705
6.

Resveratrol Sustains Insulin-Degrading Enzyme Activity toward Aβ42.

Krasinski CA, Ivancic VA, Zheng Q, Spratt DE, Lazo ND.

ACS Omega. 2018 Oct 31;3(10):13275-13282. doi: 10.1021/acsomega.8b01913. Epub 2018 Oct 16.

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OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.

Yuan C, Guo X, Zhou Q, Du F, Jiang W, Zhou X, Liu P, Chi T, Ji X, Gao J, Chen C, Lang H, Xu J, Liu D, Yang Y, Qiu S, Tang X, Chen G, Zou L.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):161-180. doi: 10.1016/j.bbadis.2018.10.028. Epub 2018 Oct 30.

PMID:
30389579
10.

Photobiomodulation using a low-level light-emitting diode improves cognitive dysfunction in the 5XFAD mouse model of Alzheimer's disease.

Cho GM, Lee SY, Park JH, Kim MJ, Park KJ, Choi BT, Shin YI, Kim NG, Shin HK.

J Gerontol A Biol Sci Med Sci. 2018 Oct 20. doi: 10.1093/gerona/gly240. [Epub ahead of print]

PMID:
30346494
11.

The core sequence of PIF competes for insulin/amyloid β in insulin degrading enzyme: potential treatment for Alzheimer's disease.

Hayrabedyan S, Todorova K, Spinelli M, Barnea ER, Mueller M.

Oncotarget. 2018 Sep 21;9(74):33884-33895. doi: 10.18632/oncotarget.26057. eCollection 2018 Sep 21.

12.

Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme.

Ivancic VA, Krasinski CA, Zheng Q, Meservier RJ, Spratt DE, Lazo ND.

Biosci Rep. 2018 Nov 7;38(6). pii: BSR20181416. doi: 10.1042/BSR20181416. Print 2018 Dec 21.

13.

Dendrobium polysaccharides attenuate cognitive impairment in senescence-accelerated mouse prone 8 mice via modulation of microglial activation.

Feng CZ, Cao L, Luo D, Ju LS, Yang JJ, Xu XY, Yu YP.

Brain Res. 2019 Feb 1;1704:1-10. doi: 10.1016/j.brainres.2018.09.030. Epub 2018 Sep 22.

PMID:
30253123
14.

Computer-aided identification of protein targets of four polyphenols in Alzheimer's disease (AD) and validation in a mouse AD model.

Li CY, Meng P, Zhang BZ, Kang H, Wen HL, Schluesener H, Cao ZW, Zhang ZY.

J Biomed Res. 2018 Sep 21. doi: 10.7555/JBR.32.20180021. [Epub ahead of print]

15.

A pectin from fruits of Lycium barbarum L. decreases β-amyloid peptide production through modulating APP processing.

Zhou L, Liao W, Zeng H, Yao Y, Chen X, Ding K.

Carbohydr Polym. 2018 Dec 1;201:65-74. doi: 10.1016/j.carbpol.2018.08.050. Epub 2018 Aug 15.

PMID:
30241864
16.

Effect of growth differentiation factor-15 secreted by human umbilical cord blood-derived mesenchymal stem cells on amyloid beta levels in in vitro and in vivo models of Alzheimer's disease.

Kim DH, Lee D, Lim H, Choi SJ, Oh W, Yang YS, Chang JH, Jeon HB.

Biochem Biophys Res Commun. 2018 Oct 12;504(4):933-940. doi: 10.1016/j.bbrc.2018.09.012. Epub 2018 Sep 14.

PMID:
30224067
17.

Effects of Tea Catechins on Alzheimer's Disease: Recent Updates and Perspectives.

Ide K, Matsuoka N, Yamada H, Furushima D, Kawakami K.

Molecules. 2018 Sep 14;23(9). pii: E2357. doi: 10.3390/molecules23092357. Review.

18.

Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.

Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH.

Neurochem Int. 2018 Nov;120:238-250. doi: 10.1016/j.neuint.2018.09.005. Epub 2018 Sep 11.

PMID:
30217465
19.
20.

Chia Seed Does Not Improve Cognitive Impairment in SAMP8 Mice Fed with High Fat Diet.

Rui Y, Lv M, Chang J, Xu J, Qin L, Wan Z.

Nutrients. 2018 Aug 14;10(8). pii: E1084. doi: 10.3390/nu10081084.

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